Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA

por Despras, Emmanuelle, Sittewelle, Méghane, Pouvelle, Caroline, Delrieu, Noémie, Cordonnier, Agnès M, Kannouche, Patricia L
Publicado 2016

Changes in the architecture and abundance of replication intermediates delineate the chronology of DNA damage tolerance pathways at UV-stalled replication forks in human cells

por Benureau, Yann, Pouvelle, Caroline, Dupaigne, Pauline, Baconnais, Sonia, Moreira Tavares, Eliana, Mazón, Gerard, Despras, Emmanuelle, Le Cam, Eric, Kannouche, Patricia L
Publicado 2022

The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells

por Bacquin, Agathe, Pouvelle, Caroline, Siaud, Nicolas, Perderiset, Mylène, Salomé-Desnoulez, Sophie, Tellier-Lebegue, Carine, Lopez, Bernard, Charbonnier, Jean-Baptiste, Kannouche, Patricia L.
Publicado 2013

First description of ultramutated endometrial cancer caused by germline loss-of-function and somatic exonuclease domain mutations in POLE gene

por Rosa, Reginaldo Cruz Alves, Yurchenko, Andrey A., Chahud, Fernando, Ribeiro-Silva, Alfredo, Brunaldi, Mariângela Ottoboni, Silva, Wilson Araújo, Kannouche, Patricia L., Nikolaev, Sergey, Ferraz, Victor Evangelista de Faria
Publicado 2020

Predicting immunotherapy outcomes in patients with MSI tumors using NLR and CT global tumor volume

por Belkouchi, Younes, Nebot-Bral, Laetitia, Lawrance, Littisha, Kind, Michele, David, Clémence, Ammari, Samy, Cournède, Paul-Henry, Talbot, Hugues, Vuagnat, Perrine, Smolenschi, Cristina, Kannouche, Patricia L., Chaput, Nathalie, Lassau, Nathalie, Hollebecque, Antoine
Publicado 2022

Genomic mutation landscape of skin cancers from DNA repair-deficient xeroderma pigmentosum patients

por Yurchenko, Andrey A., Rajabi, Fatemeh, Braz-Petta, Tirzah, Fassihi, Hiva, Lehmann, Alan, Nishigori, Chikako, Wang, Jinxin, Padioleau, Ismael, Gunbin, Konstantin, Panunzi, Leonardo, Morice-Picard, Fanny, Laplante, Pierre, Robert, Caroline, Kannouche, Patricia L., Menck, Carlos F. M., Sarasin, Alain, Nikolaev, Sergey I.
Publicado 2023

Targeting genome integrity dysfunctions impedes metastatic potency in non–small cell lung cancer circulating tumor cell–derived explants

por Tayoun, Tala, Faugeroux, Vincent, Oulhen, Marianne, Déas, Olivier, Michels, Judith, Brulle-Soumare, Laura, Cairo, Stefano, Scoazec, Jean-Yves, Marty, Virginie, Aberlenc, Agathe, Planchard, David, Remon, Jordi, Ponce, Santiago, Besse, Benjamin, Kannouche, Patricia L., Judde, Jean-Gabriel, Pawlikowska, Patrycja, Farace, Françoise
Publicado 2022

DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability

por Ben Yamin, Barbara, Ahmed‐Seghir, Sana, Tomida, Junya, Despras, Emmanuelle, Pouvelle, Caroline, Yurchenko, Andrey, Goulas, Jordane, Corre, Raphael, Delacour, Quentin, Droin, Nathalie, Dessen, Philippe, Goidin, Didier, Lange, Sabine S, Bhetawal, Sarita, Mitjavila‐Garcia, Maria Teresa, Baldacci, Giuseppe, Nikolaev, Sergey, Cadoret, Jean Charles, Wood, Richard D, Kannouche, Patricia L
Publicado 2021

XPC and POLH/XPV Genes Mutated in a Genetic Cluster of Xeroderma Pigmentosum Patients in Northeast Brazil

por Castro, Ligia Pereira, Batista-Vieira, Danilo, de Souza, Tiago Antonio, Timoteo, Ana Rafaela de Souza, Coutinho, Jessica Dayanna Landivar, Pinheiro de Almeida, Isabel Cristina, Henriques, Sheila Ramos de Miranda, de Azevedo, Fabio Medeiros, Rosa, Reginaldo Cruz Alves, Kannouche, Patricia L, Sarasin, Alain, Menck, Carlos Frederico Martins, Petta, Tirzah Braz
Publicado 2022