The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer()

por Kansanen, Emilia, Kuosmanen, Suvi M., Leinonen, Hanna, Levonen, Anna-Liisa
Publicado 2013

MicroRNA Profiling Reveals Distinct Profiles for Tissue-Derived and Cultured Endothelial Cells

por Kuosmanen, Suvi M., Kansanen, Emilia, Sihvola, Virve, Levonen, Anna-Liisa
Publicado 2017

MicroRNAs mediate the senescence-associated decline of NRF2 in endothelial cells

por Kuosmanen, Suvi M., Sihvola, Virve, Kansanen, Emilia, Kaikkonen, Minna U., Levonen, Anna-Liisa
Publicado 2018

Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics

por Levonen, Anna-Liisa, Hill, Bradford G., Kansanen, Emilia, Zhang, Jianhua, Darley-Usmar, Victor M.
Publicado 2014

The KEAP1-NRF2 pathway: Targets for therapy and role in cancer

por Adinolfi, Simone, Patinen, Tommi, Jawahar Deen, Ashik, Pitkänen, Sini, Härkönen, Jouni, Kansanen, Emilia, Küblbeck, Jenni, Levonen, Anna-Liisa
Publicado 2023

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

por Kaikkonen, Minna U., Niskanen, Henri, Romanoski, Casey E., Kansanen, Emilia, Kivelä, Annukka M., Laitalainen, Jarkko, Heinz, Sven, Benner, Christopher, Glass, Christopher K., Ylä-Herttuala, Seppo
Publicado 2014

Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis

por Jobbagy, Soma, Vitturi, Dario A., Salvatore, Sonia R., Turell, Lucía, Pires, Maria F., Kansanen, Emilia, Batthyany, Carlos, Lancaster, Jack R., Freeman, Bruce A., Schopfer, Francisco J.
Publicado 2018

In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury—Lessons Learned

por Lipponen, Anssi, Natunen, Teemu, Hujo, Mika, Ciszek, Robert, Hämäläinen, Elina, Tohka, Jussi, Hiltunen, Mikko, Paananen, Jussi, Poulsen, David, Kansanen, Emilia, Ekolle Ndode-Ekane, Xavier, Levonen, Anna-Liisa, Pitkänen, Asla
Publicado 2019

NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation

por Kuosmanen, Suvi M, Kansanen, Emilia, Kaikkonen, Minna U, Sihvola, Virve, Pulkkinen, Kati, Jyrkkänen, Henna-Kaisa, Tuoresmäki, Pauli, Hartikainen, Juha, Hippeläinen, Mikko, Kokki, Hannu, Tavi, Pasi, Heikkinen, Sami, Levonen, Anna-Liisa
Publicado 2018

The Effects of Sequence Variation on Genome-wide NRF2 Binding—New Target Genes and Regulatory SNPs

por Kuosmanen, Suvi M., Viitala, Sari, Laitinen, Tuomo, Peräkylä, Mikael, Pölönen, Petri, Kansanen, Emilia, Leinonen, Hanna, Raju, Suresh, Wienecke-Baldacchino, Anke, Närvänen, Ale, Poso, Antti, Heinäniemi, Merja, Heikkinen, Sami, Levonen, Anna-Liisa
Publicado 2016

NRF2 is a key regulator of endothelial microRNA expression under proatherogenic stimuli

por Linna-Kuosmanen, Suvi, Tomas Bosch, Vanesa, Moreau, Pierre R, Bouvy-Liivrand, Maria, Niskanen, Henri, Kansanen, Emilia, Kivelä, Annukka, Hartikainen, Juha, Hippeläinen, Mikko, Kokki, Hannu, Tavi, Pasi, Levonen, Anna-Liisa, Kaikkonen, Minna U
Publicado 2020

Novel Keto-phospholipids Are Generated by Monocytes and Macrophages, Detected in Cystic Fibrosis, and Activate Peroxisome Proliferator-activated Receptor-γ

por Hammond, Victoria J., Morgan, Alwena H., Lauder, Sarah, Thomas, Christopher P., Brown, Sarah, Freeman, Bruce A., Lloyd, Clare M., Davies, Jane, Bush, Andrew, Levonen, Anna-Liisa, Kansanen, Emilia, Villacorta, Luis, Chen, Y. Eugene, Porter, Ned, Garcia-Diaz, Yoel M., Schopfer, Francisco J., O'Donnell, Valerie B.
Publicado 2012