The role of the ER stress-response protein PERK in rhodopsin retinitis pigmentosa

por Athanasiou, Dimitra, Aguila, Monica, Bellingham, James, Kanuga, Naheed, Adamson, Peter, Cheetham, Michael E
Publicado 2017

The Inherited Blindness Protein AIPL1 Regulates the Ubiquitin-Like FAT10 Pathway

por Bett, John S., Kanuga, Naheed, Richet, Emma, Schmidtke, Gunter, Groettrup, Marcus, Cheetham, Michael E., van der Spuy, Jacqueline
Publicado 2012

The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control

por Athanasiou, Dimitra, Bevilacqua, Dalila, Aguila, Monica, McCulley, Caroline, Kanuga, Naheed, Iwawaki, Takao, Paul Chapple, J., Cheetham, Michael E.
Publicado 2014

BiP prevents rod opsin aggregation

por Athanasiou, Dimitra, Kosmaoglou, Maria, Kanuga, Naheed, Novoselov, Sergey S., Paton, Adrienne W., Paton, James C., Chapple, J. Paul, Cheetham, Michael E.
Publicado 2012

Molecular Chaperone Mediated Late-Stage Neuroprotection in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis

por Novoselov, Sergey S., Mustill, Wendy J., Gray, Anna L., Dick, James R., Kanuga, Naheed, Kalmar, Bernadett, Greensmith, Linda, Cheetham, Michael E.
Publicado 2013

Blue cone monochromacy: Causative mutations and associated phenotypes

por Gardner, Jessica C., Michaelides, Michel, Holder, Graham E., Kanuga, Naheed, Webb, Tom R., Mollon, John D., Moore, Anthony T., Hardcastle, Alison J.
Publicado 2009

The Nance–Horan syndrome protein encodes a functional WAVE homology domain (WHD) and is important for co-ordinating actin remodelling and maintaining cell morphology

por Brooks, Simon P., Coccia, Margherita, Tang, Hao R., Kanuga, Naheed, Machesky, Laura M., Bailly, Maryse, Cheetham, Michael E., Hardcastle, Alison J.
Publicado 2010

Hsp90 inhibition protects against inherited retinal degeneration

por Aguilà, Mònica, Bevilacqua, Dalila, McCulley, Caroline, Schwarz, Nele, Athanasiou, Dimitra, Kanuga, Naheed, Novoselov, Sergey S., Lange, Clemens A.K., Ali, Robin R., Bainbridge, James W., Gias, Carlos, Coffey, Peter J., Garriga, Pere, Cheetham, Michael E.
Publicado 2014

Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells

por Schwarz, Nele, Carr, Amanda-Jayne, Lane, Amelia, Moeller, Fabian, Chen, Li Li, Aguilà, Mònica, Nommiste, Britta, Muthiah, Manickam N., Kanuga, Naheed, Wolfrum, Uwe, Nagel-Wolfrum, Kerstin, da Cruz, Lyndon, Coffey, Peter J., Cheetham, Michael E., Hardcastle, Alison J.
Publicado 2015

Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups

por Parfitt, David A., Lane, Amelia, Ramsden, Conor M., Carr, Amanda-Jayne F., Munro, Peter M., Jovanovic, Katarina, Schwarz, Nele, Kanuga, Naheed, Muthiah, Manickam N., Hull, Sarah, Gallo, Jean-Marc, da Cruz, Lyndon, Moore, Anthony T., Hardcastle, Alison J., Coffey, Peter J., Cheetham, Michael E.
Publicado 2016

X-linked cataract and Nance-Horan syndrome are allelic disorders

por Coccia, Margherita, Brooks, Simon P., Webb, Tom R., Christodoulou, Katja, Wozniak, Izabella O., Murday, Victoria, Balicki, Martha, Yee, Harris A., Wangensteen, Teresia, Riise, Ruth, Saggar, Anand K., Park, Soo-Mi, Kanuga, Naheed, Francis, Peter J., Maher, Eamonn R., Moore, Anthony T., Russell-Eggitt, Isabelle M., Hardcastle, Alison J.
Publicado 2009

Three Different Cone Opsin Gene Array Mutational Mechanisms with Genotype–Phenotype Correlation and Functional Investigation of Cone Opsin Variants

por Gardner, Jessica C, Liew, Gerald, Quan, Ying-Hua, Ermetal, Burcu, Ueyama, Hisao, Davidson, Alice E, Schwarz, Nele, Kanuga, Naheed, Chana, Ravinder, Maher, Eamonn R, Webster, Andrew R, Holder, Graham E, Robson, Anthony G, Cheetham, Michael E, Liebelt, Jan, Ruddle, Jonathan B, Moore, Anthony T, Michaelides, Michel, Hardcastle, Alison J
Publicado 2014

Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration

por Athanasiou, Dimitra, Aguila, Monica, Opefi, Chikwado A., South, Kieron, Bellingham, James, Bevilacqua, Dalila, Munro, Peter M., Kanuga, Naheed, Mackenzie, Francesca E., Dubis, Adam M., Georgiadis, Anastasios, Graca, Anna B., Pearson, Rachael A., Ali, Robin R., Sakami, Sanae, Palczewski, Krzysztof, Sherman, Michael Y., Reeves, Philip J., Cheetham, Michael E.
Publicado 2017