Studying the organization of DNA repair by single-cell and single-molecule imaging

por Uphoff, Stephan, Kapanidis, Achillefs N.
Publicado 2014

Single-molecule and super-resolution imaging of transcription in living bacteria

por Stracy, Mathew, Kapanidis, Achillefs N.
Publicado 2017

Recent Advances in Understanding σ70-Dependent Transcription Initiation Mechanisms

por Mazumder, Abhishek, Kapanidis, Achillefs N.
Publicado 2019

Understanding Protein Mobility in Bacteria by Tracking Single Molecules

por Kapanidis, Achillefs N., Uphoff, Stephan, Stracy, Mathew
Publicado 2018

Visualizing Protein-DNA Interactions in Live Bacterial Cells Using Photoactivated Single-molecule Tracking

por Uphoff, Stephan, Sherratt, David J., Kapanidis, Achillefs N.
Publicado 2014

Rediscovering Bacteria through Single-Molecule Imaging in Living Cells

por Kapanidis, Achillefs N., Lepore, Alessia, El Karoui, Meriem
Publicado 2018

Transcription initiation at a consensus bacterial promoter proceeds via a ‘bind-unwind-load-and-lock’ mechanism

por Mazumder, Abhishek, Ebright, Richard H, Kapanidis, Achillefs N
Publicado 2021

The Rate-limiting Step of DNA Synthesis by DNA Polymerase Occurs in the Fingers-closed Conformation

por Evans, Geraint W., Craggs, Timothy, Kapanidis, Achillefs N.
Publicado 2022

Solution-Based Single-Molecule FRET Studies of K(+) Channel Gating in a Lipid Bilayer

por Sadler, Emma E., Kapanidis, Achillefs N., Tucker, Stephen J.
Publicado 2016

Closing and opening of the RNA polymerase trigger loop

por Mazumder, Abhishek, Lin, Miaoxin, Kapanidis, Achillefs N., Ebright, Richard H.
Publicado 2020

T7 RNA Polymerase Functions In Vitro without Clustering

por Finan, Kieran, Torella, Joseph P., Kapanidis, Achillefs N., Cook, Peter R.
Publicado 2012

Internalization and Observation of Fluorescent Biomolecules in Living Microorganisms via Electroporation

por Aigrain, Louise, Sustarsic, Marko, Crawford, Robert, Plochowietz, Anne, Kapanidis, Achillefs N.
Publicado 2015

In vivo single-RNA tracking shows that most tRNA diffuses freely in live bacteria

por Plochowietz, Anne, Farrell, Ian, Smilansky, Zeev, Cooperman, Barry S., Kapanidis, Achillefs N.
Publicado 2017

Real-time single-molecule studies of the motions of DNA polymerase fingers illuminate DNA synthesis mechanisms

por Evans, Geraint W., Hohlbein, Johannes, Craggs, Timothy, Aigrain, Louise, Kapanidis, Achillefs N.
Publicado 2015

DNA Polymerase Conformational Dynamics and the Role of Fidelity-Conferring Residues: Insights from Computational Simulations

por Meli, Massimiliano, Sustarsic, Marko, Craggs, Timothy D., Kapanidis, Achillefs N., Colombo, Giorgio
Publicado 2016

RNA polymerase clamp conformational dynamics: long-lived states and modulation by crowding, cations, and nonspecific DNA binding

por Mazumder, Abhishek, Wang, Anna, Uhm, Heesoo, Ebright, Richard H, Kapanidis, Achillefs N
Publicado 2021

The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp

por Duchi, Diego, Mazumder, Abhishek, Malinen, Anssi M, Ebright, Richard H, Kapanidis, Achillefs N
Publicado 2018

Real-time analysis of single influenza virus replication complexes reveals large promoter-dependent differences in initiation dynamics

por Robb, Nicole C, te Velthuis, Aartjan J W, Fodor, Ervin, Kapanidis, Achillefs N
Publicado 2019

Transient non-specific DNA binding dominates the target search of bacterial DNA-binding proteins

por Stracy, Mathew, Schweizer, Jakob, Sherratt, David J., Kapanidis, Achillefs N., Uphoff, Stephan, Lesterlin, Christian
Publicado 2021

RNA polymerase redistribution supports growth in E. coli strains with a minimal number of rRNA operons

por Fan, Jun, El Sayyed, Hafez, Pambos, Oliver J, Stracy, Mathew, Kyropoulos, Jingwen, Kapanidis, Achillefs N
Publicado 2023