Information sharing in high-dimensional gene expression data for improved parameter estimation in concentration-response modelling

por Kappenberg, Franziska, Rahnenführer, Jörg
Publicado 2023

Benefit of using interaction effects for the analysis of high-dimensional time-response or dose-response data for two-group comparisons

por Duda, Julia C., Drenda, Carolin, Kästel, Hue, Rahnenführer, Jörg, Kappenberg, Franziska
Publicado 2023

Comparison of observation-based and model-based identification of alert concentrations from concentration–expression data

por Kappenberg, Franziska, Grinberg, Marianna, Jiang, Xiaoqi, Kopp-Schneider, Annette, Hengstler, Jan G, Rahnenführer, Jörg
Publicado 2021

Guidance for statistical design and analysis of toxicological dose–response experiments, based on a comprehensive literature review

por Kappenberg, Franziska, Duda, Julia C., Schürmeyer, Leonie, Gül, Onur, Brecklinghaus, Tim, Hengstler, Jan G., Schorning, Kirsten, Rahnenführer, Jörg
Publicado 2023

Handling deviating control values in concentration-response curves

por Kappenberg, Franziska, Brecklinghaus, Tim, Albrecht, Wiebke, Blum, Jonathan, van der Wurp, Carola, Leist, Marcel, Hengstler, Jan G., Rahnenführer, Jörg
Publicado 2020

Transcriptome-based prediction of drugs, inhibiting cardiomyogenesis in human induced pluripotent stem cells

por Cherianidou, Anna, Kappenberg, Franziska, Seidel, Florian, Acharya, Aviseka, Papazoglou, Panagiota, Srinivasan, Sureshkumar Perumal, Hescheler, Jürgen, Peng, Luying, Leist, Marcel, Hengstler, Jan G., Rahnenführer, Jörg, Sachinidis, Agapios
Publicado 2023

Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test

por Cherianidou, Anna, Seidel, Florian, Kappenberg, Franziska, Dreser, Nadine, Blum, Jonathan, Waldmann, Tanja, Blüthgen, Nils, Meisig, Johannes, Madjar, Katrin, Henry, Margit, Rotshteyn, Tamara, Marchan, Rosemarie, Edlund, Karolina, Leist, Marcel, Rahnenführer, Jörg, Sachinidis, Agapios, Hengstler, Jan G.
Publicado 2022

Discordance of HER2-Low between Primary Tumors and Matched Distant Metastases in Breast Cancer

por Almstedt, Katrin, Krauthauser, Lisa, Kappenberg, Franziska, Wagner, Daniel-Christoph, Heimes, Anne-Sophie, Battista, Marco J., Anic, Katharina, Krajnak, Slavomir, Lebrecht, Antje, Schwab, Roxana, Brenner, Walburgis, Weikel, Wolfgang, Rahnenführer, Jörg, Hengstler, Jan G., Roth, Wilfried, Hasenburg, Annette, Stewen, Kathrin, Schmidt, Marcus
Publicado 2023

High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation

por Seidel, Florian, Cherianidou, Anna, Kappenberg, Franziska, Marta, Miriam, Dreser, Nadine, Blum, Jonathan, Waldmann, Tanja, Blüthgen, Nils, Meisig, Johannes, Madjar, Katrin, Henry, Margit, Rotshteyn, Tamara, Scholtz-Illigens, Andreas, Marchan, Rosemarie, Edlund, Karolina, Leist, Marcel, Rahnenführer, Jörg, Sachinidis, Agapios, Hengstler, Jan Georg
Publicado 2022

Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression

por Ghallab, Ahmed, Myllys, Maiju, Friebel, Adrian, Duda, Julia, Edlund, Karolina, Halilbasic, Emina, Vucur, Mihael, Hobloss, Zaynab, Brackhagen, Lisa, Begher-Tibbe, Brigitte, Hassan, Reham, Burke, Michael, Genc, Erhan, Frohwein, Lynn Johann, Hofmann, Ute, Holland, Christian H., González, Daniela, Keller, Magdalena, Seddek, Abdel-latif, Abbas, Tahany, Mohammed, Elsayed S. I., Teufel, Andreas, Itzel, Timo, Metzler, Sarah, Marchan, Rosemarie, Cadenas, Cristina, Watzl, Carsten, Nitsche, Michael A., Kappenberg, Franziska, Luedde, Tom, Longerich, Thomas, Rahnenführer, Jörg, Hoehme, Stefan, Trauner, Michael, Hengstler, Jan G.
Publicado 2021

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

por Ghallab, Ahmed, Hassan, Reham, Hofmann, Ute, Friebel, Adrian, Hobloss, Zaynab, Brackhagen, Lisa, Begher-Tibbe, Brigitte, Myllys, Maiju, Reinders, Joerg, Overbeck, Nina, Sezgin, Selahaddin, Zühlke, Sebastian, Seddek, Abdel-latif, Murad, Walaa, Brecklinghaus, Tim, Kappenberg, Franziska, Rahnenführer, Jörg, González, Daniela, Goldring, Christopher, Copple, Ian M., Marchan, Rosemarie, Longerich, Thomas, Vucur, Mihael, Luedde, Tom, Urban, Stephan, Canbay, Ali, Schreiter, Thomas, Trauner, Michael, Akakpo, Jephte Y., Olyaee, Mojtaba, Curry, Steven C., Sowa, Jan-Peter, Jaeschke, Hartmut, Hoehme, Stefan, Hengstler, Jan G.
Publicado 2022