Depletion of Luminal Pyridine Nucleotides in the Endoplasmic Reticulum Activates Autophagy with the Involvement of mTOR Pathway

por Kapuy, Orsolya, Bánhegyi, Gábor
Publicado 2013

Chloroquine and COVID-19—A systems biology model uncovers the drug’s detrimental effect on autophagy and explains its failure

por Kapuy, Orsolya, Korcsmáros, Tamás
Publicado 2022

GADD34 Keeps the mTOR Pathway Inactivated in Endoplasmic Reticulum Stress Related Autophagy

por Holczer, Marianna, Bánhegyi, Gábor, Kapuy, Orsolya
Publicado 2016

mTOR inhibition increases cell viability via autophagy induction during endoplasmic reticulum stress – An experimental and modeling study

por Kapuy, Orsolya, Vinod, P.K., Bánhegyi, Gábor
Publicado 2014

Computational modelling of meiotic entry and commitment

por Bhola, Tanvi, Kapuy, Orsolya, Vinod, P. K.
Publicado 2018

Therapeutic Approach of KRAS Mutant Tumours by the Combination of Pharmacologic Ascorbate and Chloroquine

por Kapuy, Orsolya, Makk-Merczel, Kinga, Szarka, András
Publicado 2021

Mitotic exit in mammalian cells

por Kapuy, Orsolya, He, Enuo, Uhlmann, Frank, Novák, Béla
Publicado 2009

Autophagy-dependent survival is controlled with a unique regulatory network upon various cellular stress events

por Kapuy, Orsolya, Holczer, Marianna, Márton, Margita, Korcsmáros, Tamás
Publicado 2021

Irreversibility of mitotic exit is the consequence of systems level feedback

por López-Avilés, Sandra, Kapuy, Orsolya, Novák, Béla, Uhlmann, Frank
Publicado 2009

A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress

por Holczer, Marianna, Márton, Margita, Kurucz, Anita, Bánhegyi, Gábor, Kapuy, Orsolya
Publicado 2015

Systems-Level Feedbacks of NRF2 Controlling Autophagy upon Oxidative Stress Response

por Kapuy, Orsolya, Papp, Diána, Vellai, Tibor, Bánhegyi, Gábor, Korcsmáros, Tamás
Publicado 2018

NRF2-regulated cell cycle arrest at early stage of oxidative stress response mechanism

por Márton, Margita, Tihanyi, Nikolett, Gyulavári, Pál, Bánhegyi, Gábor, Kapuy, Orsolya
Publicado 2018

Fine-Tuning of mTORC1-ULK1-PP2A Regulatory Triangle Is Crucial for Robust Autophagic Response upon Cellular Stress

por Hajdú, Bence, Holczer, Marianna, Horváth, Gergely, Szederkényi, Gábor, Kapuy, Orsolya
Publicado 2022

Overexpression limits of fission yeast cell-cycle regulators in vivo and in silico

por Moriya, Hisao, Chino, Ayako, Kapuy, Orsolya, Csikász-Nagy, Attila, Novák, Béla
Publicado 2011

Oscillation of Autophagy Induction under Cellular Stress and What Lies behind It, a Systems Biology Study

por Hajdú, Bence, Csabai, Luca, Márton, Margita, Holczer, Marianna, Korcsmáros, Tamás, Kapuy, Orsolya
Publicado 2023

A Systems Biological View of Life-and-Death Decision with Respect to Endoplasmic Reticulum Stress—The Role of PERK Pathway

por Márton, Margita, Kurucz, Anita, Lizák, Beáta, Margittai, Éva, Bánhegyi, Gábor, Kapuy, Orsolya
Publicado 2017

Epigallocatechin-3-Gallate (EGCG) Promotes Autophagy-Dependent Survival via Influencing the Balance of mTOR-AMPK Pathways upon Endoplasmic Reticulum Stress

por Holczer, Marianna, Besze, Boglárka, Zámbó, Veronika, Csala, Miklós, Bánhegyi, Gábor, Kapuy, Orsolya
Publicado 2018

A Double Negative Feedback Loop between mTORC1 and AMPK Kinases Guarantees Precise Autophagy Induction upon Cellular Stress

por Holczer, Marianna, Hajdú, Bence, Lőrincz, Tamás, Szarka, András, Bánhegyi, Gábor, Kapuy, Orsolya
Publicado 2019

Fine-tuning of AMPK–ULK1–mTORC1 regulatory triangle is crucial for autophagy oscillation

por Holczer, Marianna, Hajdú, Bence, Lőrincz, Tamás, Szarka, András, Bánhegyi, Gábor, Kapuy, Orsolya
Publicado 2020

A systems biological analysis of the ATF4‐GADD34‐CHOP regulatory triangle upon endoplasmic reticulum stress

por Márton, Margita, Bánhegyi, Gábor, Gyöngyösi, Norbert, Kálmán, Eszter Éva, Pettkó‐Szandtner, Aladár, Káldi, Krisztina, Kapuy, Orsolya
Publicado 2022