Protection from COVID-19 disease in hamsters vaccinated with subunit SARS-CoV-2 S1 mucosal vaccines adjuvanted with different adjuvants

por Sui, Yongjun, Andersen, Hanne, Li, Jianping, Hoang, Tanya, Bekele, Yonas, Kar, Swagata, Lewis, Mark G., Berzofsky, Jay A.
Publicado 2023

Synthetic multiantigen MVA vaccine COH04S1 and variant-specific derivatives protect Syrian hamsters from SARS-CoV-2 Omicron subvariants

por Wussow, Felix, Kha, Mindy, Kim, Taehyun, Ly, Minh, Yll-Pico, Marcal, Kar, Swagata, Lewis, Mark G., Chiuppesi, Flavia, Diamond, Don J.
Publicado 2023

COH04S1 and beta sequence-modified vaccine protect hamsters from SARS-CoV-2 variants

por Wussow, Felix, Kha, Mindy, Faircloth, Katelyn, Nguyen, Vu H., Iniguez, Angelina, Martinez, Joy, Park, Yoonsuh, Nguyen, Jenny, Kar, Swagata, Andersen, Hanne, Lewis, Mark G., Chiuppesi, Flavia, Diamond, Don J.
Publicado 2022

A Human-Immune-System (HIS) humanized mouse model (DRAGA: HLA-A2. HLA-DR4. Rag1 KO.IL-2Rγc KO. NOD) for COVID-19

por Brumeanu, Teodor-D., Vir, Pooja, Karim, Ahmad Faisal, Kar, Swagata, Benetiene, Dalia, Lok, Megan, Greenhouse, Jack, Putmon-Taylor, Tammy, Kitajewski, Christopher, Chung, Kevin K., Pratt, Kathleen P., Casares, Sofia A.
Publicado 2021

Human-Immune-System (HIS) humanized mouse model (DRAGA: HLA-A2.HLA-DR4.Rag1KO.IL-2RγcKO.NOD) for COVID-19

por Brumeanu, Teodor-D., Vir, Pooja, Karim, Ahmad Faisal, Kar, Swagata, Benetiene, Dalia, Lok, Megan, Greenhouse, Jack, Putmon-Taylor, Tammy, Kitajewski, Christopher, Chung, Kevin K., Pratt, Kathleen P., Casares, Sofia A.
Publicado 2022

One dose of COVID-19 nanoparticle vaccine REVC-128 protects against SARS-CoV-2 challenge at two weeks post-immunization

por Gu, Maggie, Torres, Jonathan L., Li, Yijia, Van Ry, Alex, Greenhouse, Jack, Wallace, Shannon, Chiang, Chi-I, Pessaint, Laurent, Jackson, Abigail M., Porto, Maciel, Kar, Swagata, Li, Yuxing, Ward, Andrew B., Wang, Yimeng
Publicado 2021

Beta-containing bivalent SARS-CoV-2 protein vaccine elicits durable broad neutralization in macaques and protection in hamsters

por Berry, Catherine, Pavot, Vincent, Anosova, Natalie G., Kishko, Michael, Li, Lu, Tibbitts, Tim, Raillard, Alice, Gautheron, Sylviane, Cummings, Sheila, Bangari, Dinesh S., Kar, Swagata, Atyeo, Caroline, Deng, Yixiang, Alter, Galit, Gutzeit, Cindy, Koutsoukos, Marguerite, Chicz, Roman M., Lecouturier, Valerie
Publicado 2023

Reduced pathogenicity of the SARS-CoV-2 omicron variant in hamsters

por McMahan, Katherine, Giffin, Victoria, Tostanoski, Lisa H., Chung, Benjamin, Siamatu, Mazuba, Suthar, Mehul S., Halfmann, Peter, Kawaoka, Yoshihiro, Piedra-Mora, Cesar, Jain, Neharika, Ducat, Sarah, Kar, Swagata, Andersen, Hanne, Lewis, Mark G., Martinot, Amanda J., Barouch, Dan H.
Publicado 2022

Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2

por Shi, Guoli, Chiramel, Abhilash I., Li, Tiansheng, Lai, Kin Kui, Kenney, Adam D., Zani, Ashley, Eddy, Adrian C., Majdoul, Saliha, Zhang, Lizhi, Dempsey, Tirhas, Beare, Paul A., Kar, Swagata, Yewdell, Jonathan W., Best, Sonja M., Yount, Jacob S., Compton, Alex A.
Publicado 2022

Synthetic multiantigen MVA vaccine COH04S1 protects against SARS-CoV-2 in Syrian hamsters and non-human primates

por Chiuppesi, Flavia, Nguyen, Vu H., Park, Yoonsuh, Contreras, Heidi, Karpinski, Veronica, Faircloth, Katelyn, Nguyen, Jenny, Kha, Mindy, Johnson, Daisy, Martinez, Joy, Iniguez, Angelina, Zhou, Qiao, Kaltcheva, Teodora, Frankel, Paul, Kar, Swagata, Sharma, Ankur, Andersen, Hanne, Lewis, Mark G., Shostak, Yuriy, Wussow, Felix, Diamond, Don J.
Publicado 2022

1355. The SARS-CoV-2 Monoclonal Antibody AZD3152 Potently Neutralizes Historical and Emerging Variants and is Being Developed for the Prevention and Treatment of COVID-19 in High-r...

por Francica, Joseph R, Cai, Yingyun, Diallo, Seme, Rosenthal, Kim, Ren, Kuishu, Flores, Daniel J, Dippel, Andrew, Wu, Yuling, Chen, Xiaoru, Cantu, Erin, Choudhary, Rakesh, Sulikowski, Michal, Adissu, Hibret, Chawla, Bhavna, Kar, Swagata, van Dyk, Nydia, Oganesyan, Vaheh, Rajan, Saravanan, Ryan, Patricia C, Loo, Yueh-Ming, Cohen, Taylor, Esser, Mark T, Blair, Wade
Publicado 2023

Mucosal administration of a live attenuated recombinant COVID-19 vaccine protects nonhuman primates from SARS-CoV-2

por Tioni, Mariana F., Jordan, Robert, Pena, Angie Silva, Garg, Aditya, Wu, Danlu, Phan, Shannon I., Weiss, Christopher M., Cheng, Xing, Greenhouse, Jack, Orekov, Tatyana, Valentin, Daniel, Kar, Swagata, Pessaint, Laurent, Andersen, Hanne, Stobart, Christopher C., Bloodworth, Melissa H., Stokes Peebles, R., Liu, Yang, Xie, Xuping, Shi, Pei-Yong, Moore, Martin L., Tang, Roderick S.
Publicado 2022

Convalescent human IgG, but not IgM, from COVID-19 survivors confers dose-dependent protection against SARS-CoV-2 replication and disease in hamsters

por King, Hannah A. D., Dussupt, Vincent, Mendez-Rivera, Letzibeth, Slike, Bonnie M., Tran, Ursula, Jackson, Nathan D., Barkei, Erica, Zemil, Michelle, Tourtellott-Fogt, Emily, Kuklis, Caitlin H., Soman, Sandrine, Ahmed, Aslaa, Porto, Maciel, Kitajewski, Christopher, Spence, Brittany, Benetiene, Dalia, Wieczorek, Lindsay, Kar, Swagata, Gromowski, Gregory, Polonis, Victoria R., Krebs, Shelly J., Modjarrad, Kayvon, Bolton, Diane L.
Publicado 2023

Immunity elicited by natural infection or Ad26.COV2.S vaccination protects hamsters against SARS-CoV-2 variants of concern

por Tostanoski, Lisa H., Yu, Jingyou, Mercado, Noe B., McMahan, Katherine, Jacob-Dolan, Catherine, Martinot, Amanda J., Piedra-Mora, Cesar, Anioke, Tochi, Chang, Aiquan, Giffin, Victoria M., Hope, David L., Wan, Huahua, Bondzie, Esther A., Mahrokhian, Shant H., Wrijil, Linda M., Bauer, Katherine, Pessaint, Laurent, Porto, Maciel, Piegols, Joseph, Faudree, Andrew, Spence, Brittany, Kar, Swagata, Amanat, Fatima, Krammer, Florian, Andersen, Hanne, Lewis, Mark G., Wegmann, Frank, Zahn, Roland, Schuitemaker, Hanneke, Barouch, Dan H.
Publicado 2021

Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters

por Tostanoski, Lisa H., Chandrashekar, Abishek, Patel, Shivani, Yu, Jingyou, Jacob-Dolan, Catherine, Chang, Aiquan, Powers, Olivia C., Sellers, Daniel, Gardner, Sarah, Barrett, Julia, Sanborn, Owen, Stephenson, Kathryn E., Ansel, Jessica L., Jaegle, Kate, Seaman, Michael S., Porto, Maciel, Lok, Megan, Spence, Brittany, Cayer, Kathleen, Nase, Danielle, Holman, Shaikim, Bradette, Heath, Kar, Swagata, Andersen, Hanne, Lewis, Mark G., Cox, Freek, Tolboom, Jeroen T. B. M., de Groot, Anne Marit, Heerwegh, Dirk, Le Gars, Mathieu, Sadoff, Jerald, Wegmann, Frank, Zahn, Roland C., Schuitemaker, Hanneke, Barouch, Dan H.
Publicado 2022

Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters

por Dalvie, Neil C., Rodriguez-Aponte, Sergio A., Hartwell, Brittany L., Tostanoski, Lisa H., Biedermann, Andrew M., Crowell, Laura E., Kaur, Kawaljit, Kumru, Ozan, Carter, Lauren, Yu, Jingyou, Chang, Aiquan, McMahan, Katherine, Courant, Thomas, Lebas, Celia, Lemnios, Ashley A., Rodrigues, Kristen A., Silva, Murillo, Johnston, Ryan S., Naranjo, Christopher A., Tracey, Mary Kate, Brady, Joseph R., Whittaker, Charles A., Yun, Dongsoo, Kar, Swagata, Porto, Maciel, Lok, Megan, Andersen, Hanne, Lewis, Mark G., Love, Kerry R., Camp, Danielle L., Silverman, Judith Maxwell, Kleanthous, Harry, Joshi, Sangeeta B., Volkin, David B., Dubois, Patrice M., Collin, Nicolas, King, Neil P., Barouch, Dan H., Irvine, Darrell J., Love, J. Christopher
Publicado 2021

Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice

por Dalvie, Neil C., Rodriguez-Aponte, Sergio A., Hartwell, Brittany L., Tostanoski, Lisa H., Biedermann, Andrew M., Crowell, Laura E., Kaur, Kawaljit, Kumru, Ozan S., Carter, Lauren, Yu, Jingyou, Chang, Aiquan, McMahan, Katherine, Courant, Thomas, Lebas, Celia, Lemnios, Ashley A., Rodrigues, Kristen A., Silva, Murillo, Johnston, Ryan S., Naranjo, Christopher A., Tracey, Mary Kate, Brady, Joseph R., Whittaker, Charles A., Yun, Dongsoo, Brunette, Natalie, Wang, Jing Yang, Walkey, Carl, Fiala, Brooke, Kar, Swagata, Porto, Maciel, Lok, Megan, Andersen, Hanne, Lewis, Mark G., Love, Kerry R., Camp, Danielle L., Silverman, Judith Maxwell, Kleanthous, Harry, Joshi, Sangeeta B., Volkin, David B., Dubois, Patrice M., Collin, Nicolas, King, Neil P., Barouch, Dan H., Irvine, Darrell J., Love, J. Christopher
Publicado 2021

mRNA-1273 Protects against SARS-CoV-2 Beta Infection in Nonhuman Primates

por Corbett, Kizzmekia S., Werner, Anne P., O’ Connell, Sarah, Gagne, Matthew, Lai, Lilin, Moliva, Juan I., Flynn, Barbara, Choi, Angela, Koch, Matthew, Foulds, Kathryn E., Andrew, Shayne F., Flebbe, Dillon R., Lamb, Evan, Nurmukhambetova, Saule T., Provost, Samantha J., Bock, Kevin W., Minai, Mahnaz, Nagata, Bianca M., Van Ry, Alex, Flinchbaugh, Zackery, Johnston, Timothy S., Mokhtari, Elham Bayat, Mudvari, Prakriti, Henry, Amy R., Laboune, Farida, Chang, Becky, Porto, Maciel, Wear, Jaclyn, Alvarado, Gabriela S., Boyoglu-Barnum, Seyhan, Todd, John-Paul M., Bart, Bridget, Cook, Anthony, Dodson, Alan, Pessaint, Laurent, Steingrebe, Katelyn, Elbashir, Sayda, Sriparna, Manjari, Pekosz, Andrew, Andersen, Hanne, Wu, Kai, Edwards, Darin K., Kar, Swagata, Lewis, Mark G., Boritz, Eli, Moore, Ian N., Carfi, Andrea, Suthar, Mehul S., McDermott, Adrian, Roederer, Mario, Nason, Martha C., Sullivan, Nancy J., Douek, Daniel C., Graham, Barney S., Seder, Robert A.
Publicado 2021

Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung

por Gagne, Matthew, Corbett, Kizzmekia S., Flynn, Barbara J., Foulds, Kathryn E., Wagner, Danielle A., Andrew, Shayne F., Todd, John-Paul M., Honeycutt, Christopher Cole, McCormick, Lauren, Nurmukhambetova, Saule T., Davis-Gardner, Meredith E., Pessaint, Laurent, Bock, Kevin W., Nagata, Bianca M., Minai, Mahnaz, Werner, Anne P., Moliva, Juan I., Tucker, Courtney, Lorang, Cynthia G., Zhao, Bingchun, McCarthy, Elizabeth, Cook, Anthony, Dodson, Alan, Teng, I-Ting, Mudvari, Prakriti, Roberts-Torres, Jesmine, Laboune, Farida, Wang, Lingshu, Goode, Adrienne, Kar, Swagata, Boyoglu-Barnum, Seyhan, Yang, Eun Sung, Shi, Wei, Ploquin, Aurélie, Doria-Rose, Nicole, Carfi, Andrea, Mascola, John R., Boritz, Eli A., Edwards, Darin K., Andersen, Hanne, Lewis, Mark G., Suthar, Mehul S., Graham, Barney S., Roederer, Mario, Moore, Ian N., Nason, Martha C., Sullivan, Nancy J., Douek, Daniel C., Seder, Robert A.
Publicado 2022

A SARS-CoV-2 spike ferritin nanoparticle vaccine protects against heterologous challenge with B.1.1.7 and B.1.351 virus variants in Syrian golden hamsters

por Wuertz, Kathryn McGuckin, Barkei, Erica K., Chen, Wei-Hung, Martinez, Elizabeth J., Lakhal-Naouar, Ines, Jagodzinski, Linda L., Paquin-Proulx, Dominic, Gromowski, Gregory D., Swafford, Isabella, Ganesh, Akshaya, Dong, Ming, Zeng, Xiankun, Thomas, Paul V., Sankhala, Rajeshwer S., Hajduczki, Agnes, Peterson, Caroline E., Kuklis, Caitlin, Soman, Sandrine, Wieczorek, Lindsay, Zemil, Michelle, Anderson, Alexander, Darden, Janice, Hernandez, Heather, Grove, Hannah, Dussupt, Vincent, Hack, Holly, de la Barrera, Rafael, Zarling, Stasya, Wood, James F., Froude, Jeffrey W., Gagne, Matthew, Henry, Amy R., Mokhtari, Elham Bayat, Mudvari, Prakriti, Krebs, Shelly J., Pekosz, Andrew S., Currier, Jeffrey R., Kar, Swagata, Porto, Maciel, Winn, Adrienne, Radzyminski, Kamil, Lewis, Mark G., Vasan, Sandhya, Suthar, Mehul, Polonis, Victoria R., Matyas, Gary R., Boritz, Eli A., Douek, Daniel C., Seder, Robert A., Daye, Sharon P., Rao, Mangala, Peel, Sheila A., Joyce, M. Gordon, Bolton, Diane L., Michael, Nelson L., Modjarrad, Kayvon
Publicado 2021