Stress and circulating cell-free mitochondrial DNA: A systematic review of human studies, physiological considerations, and technical recommendations

por Trumpff, Caroline, Michelson, Jeremy, Lagranha, Claudia J., Taleon, Veronica, Karan, Kalpita R., Sturm, Gabriel, Lindqvist, Daniel, Fernström, Johan, Moser, Dirk, Kaufman, Brett A., Picard, Martin
Publicado 2021

Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts

por Zhou, Weichen, Karan, Kalpita R., Gu, Wenjin, Klein, Hans-Ulrich, Sturm, Gabriel, De Jager, Philip L., Bennett, David A., Hirano, Michio, Picard, Martin, Mills, Ryan E
Publicado 2023

Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures

por Rausser, Shannon, Trumpff, Caroline, McGill, Marlon A, Junker, Alex, Wang, Wei, Ho, Siu-Hong, Mitchell, Anika, Karan, Kalpita R, Monk, Catherine, Segerstrom, Suzanne C, Reed, Rebecca G, Picard, Martin
Publicado 2021

Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging

por Bobba-Alves, Natalia, Sturm, Gabriel, Lin, Jue, Ware, Sarah A., Karan, Kalpita R., Monzel, Anna S., Bris, Céline, Procaccio, Vincent, Lenaers, Guy, Higgins-Chen, Albert, Levine, Morgan, Horvath, Steve, Santhanam, Balaji S., Kaufman, Brett A., Hirano, Michio, Epel, Elissa, Picard, Martin
Publicado 2023

A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations

por Sturm, Gabriel, Monzel, Anna S., Karan, Kalpita R., Michelson, Jeremy, Ware, Sarah A., Cardenas, Andres, Lin, Jue, Bris, Céline, Santhanam, Balaji, Murphy, Michael P., Levine, Morgan E., Horvath, Steve, Belsky, Daniel W., Wang, Shuang, Procaccio, Vincent, Kaufman, Brett A., Hirano, Michio, Picard, Martin
Publicado 2022

OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases

por Sturm, Gabriel, Karan, Kalpita R., Monzel, Anna S., Santhanam, Balaji, Taivassalo, Tanja, Bris, Céline, Ware, Sarah A., Cross, Marissa, Towheed, Atif, Higgins-Chen, Albert, McManus, Meagan J., Cardenas, Andres, Lin, Jue, Epel, Elissa S., Rahman, Shamima, Vissing, John, Grassi, Bruno, Levine, Morgan, Horvath, Steve, Haller, Ronald G., Lenaers, Guy, Wallace, Douglas C., St-Onge, Marie-Pierre, Tavazoie, Saeed, Procaccio, Vincent, Kaufman, Brett A., Seifert, Erin L., Hirano, Michio, Picard, Martin
Publicado 2023