GATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human iPS...

por Karhu, S. Tuuli, Kinnunen, Sini M., Tölli, Marja, Välimäki, Mika J., Szabó, Zoltán, Talman, Virpi, Ruskoaho, Heikki
Publicado 2020

Molecular Atlas of Postnatal Mouse Heart Development

por Talman, Virpi, Teppo, Jaakko, Pöhö, Päivi, Movahedi, Parisa, Vaikkinen, Anu, Karhu, S. Tuuli, Trošt, Kajetan, Suvitaival, Tommi, Heikkonen, Jukka, Pahikkala, Tapio, Kotiaho, Tapio, Kostiainen, Risto, Varjosalo, Markku, Ruskoaho, Heikki
Publicado 2018

Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds

por Karhu, S. Tuuli, Välimäki, Mika J., Jumppanen, Mikael, Kinnunen, Sini M., Pohjolainen, Lotta, Leigh, Robert S., Auno, Samuli, Földes, Gábor, Boije af Gennäs, Gustav, Yli-Kauhaluoma, Jari, Ruskoaho, Heikki, Talman, Virpi
Publicado 2018

Expanding the Paradigm of Structure-Based Drug Design: Molecular Dynamics Simulations Support the Development of New Pyridine-Based Protein Kinase C-Targeted Agonists

por Lautala, Saara, Provenzani, Riccardo, Tarvainen, Ilari, Sirna, Katia, Karhu, S. Tuuli, Grazhdankin, Evgeni, Lehtinen, Antti K., Sa’d, Hanan, Koivuniemi, Artturi, Xhaard, Henri, Tuominen, Raimo K., Talman, Virpi, Bunker, Alex, Yli-Kauhaluoma, Jari
Publicado 2023