Spacer2PAM: A computational framework to guide experimental determination of functional CRISPR-Cas system PAM sequences

por Rybnicky, Grant A, Fackler, Nicholas A, Karim, Ashty S, Köpke, Michael, Jewett, Michael C
Publicado 2022

Analysis of the Innovation Trend in Cell-Free Synthetic Biology

por Meyer, Conary, Nakamura, Yusuke, Rasor, Blake J., Karim, Ashty S., Jewett, Michael C., Tan, Cheemeng
Publicado 2021

Design of synthetic yeast promoters via tuning of nucleosome architecture

por Curran, Kathleen A., Crook, Nathan C., Karim, Ashty S., Gupta, Akash, Wagman, Allison M., Alper, Hal S.
Publicado 2014

Computationally-guided design and selection of high performing ribosomal active site mutants

por Kofman, Camila, Watkins, Andrew M, Kim, Do Soon, Willi, Jessica A, Wooldredge, Alexandra C, Karim, Ashty S, Das, Rhiju, Jewett, Michael C
Publicado 2022

Modular cell-free expression plasmids to accelerate biological design in cells

por Karim, Ashty S, Liew, Fungmin (Eric), Garg, Shivani, Vögeli, Bastian, Rasor, Blake J, Gonnot, Aislinn, Pavan, Marilene, Juminaga, Alex, Simpson, Séan D, Köpke, Michael, Jewett, Michael C
Publicado 2020

A rapid cell-free expression and screening platform for antibody discovery

por Hunt, Andrew C., Vögeli, Bastian, Hassan, Ahmed O., Guerrero, Laura, Kightlinger, Weston, Yoesep, Danielle J., Krüger, Antje, DeWinter, Madison, Diamond, Michael S., Karim, Ashty S., Jewett, Michael C.
Publicado 2023

A Low-Cost, Thermostable, Cell-Free Protein Synthesis Platform for On-Demand Production of Conjugate Vaccines

por Warfel, Katherine F., Williams, Asher, Wong, Derek A., Sobol, Sarah E., Desai, Primit, Li, Jie, Chang, Yung-Fu, DeLisa, Matthew P., Karim, Ashty S., Jewett, Michael C.
Publicado 2022

At-home, cell-free synthetic biology education modules for transcriptional regulation and environmental water quality monitoring

por Jung, Kirsten J., Rasor, Blake J., Rybnicky, Grant A., Silverman, Adam D., Standeven, Janet, Kuhn, Robert, Granito, Teresa, Ekas, Holly M., Wang, Brenda M., Karim, Ashty S., Lucks, Julius B., Jewett, Michael C.
Publicado 2023

Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria

por Vögeli, Bastian, Schulz, Luca, Garg, Shivani, Tarasava, Katia, Clomburg, James M., Lee, Seung Hwan, Gonnot, Aislinn, Moully, Elamar Hakim, Kimmel, Blaise R., Tran, Loan, Zeleznik, Hunter, Brown, Steven D., Simpson, Sean D., Mrksich, Milan, Karim, Ashty S., Gonzalez, Ramon, Köpke, Michael, Jewett, Michael C.
Publicado 2022