Three-Dimensional Neuroepithelial Culture from Human Embryonic Stem Cells and Its Use for Quantitative Conversion to Retinal Pigment Epithelium

por Zhu, Yu, Carido, Madalena, Meinhardt, Andrea, Kurth, Thomas, Karl, Mike O., Ader, Marius, Tanaka, Elly M.
Publicado 2013

Retinal Organoids from Pluripotent Stem Cells Efficiently Recapitulate Retinogenesis

por Völkner, Manuela, Zschätzsch, Marlen, Rostovskaya, Maria, Overall, Rupert W., Busskamp, Volker, Anastassiadis, Konstantinos, Karl, Mike O.
Publicado 2016

The Ternary Rab27a–Myrip–Myosin VIIa Complex Regulates Melanosome Motility in the Retinal Pigment Epithelium

por Lopes, Vanda S, Ramalho, José S, Owen, Dylan M, Karl, Mike O, Strauss, Olaf, Futter, Clare E, Seabra, Miguel C
Publicado 2007

Morpho‐Rheological Fingerprinting of Rod Photoreceptors Using Real‐Time Deformability Cytometry

por Santos‐Ferreira, Tiago, Herbig, Maik, Otto, Oliver, Carido, Madalena, Karl, Mike O., Michalakis, Stylianos, Guck, Jochen, Ader, Marius
Publicado 2019

Retinal cell death dependent reactive proliferative gliosis in the mouse retina

por Sardar Pasha, Sheik Pran Babu, Münch, Robert, Schäfer, Patrick, Oertel, Peter, Sykes, Alex M., Zhu, Yiqing, Karl, Mike O.
Publicado 2017

Mouse Retinal Organoid Growth and Maintenance in Longer-Term Culture

por Völkner, Manuela, Kurth, Thomas, Schor, Jana, Ebner, Lynn J. A., Bardtke, Lara, Kavak, Cagri, Hackermüller, Jörg, Karl, Mike O.
Publicado 2021

Genome-Wide Analysis of Müller Glial Differentiation Reveals a Requirement for Notch Signaling in Postmitotic Cells to Maintain the Glial Fate

por Nelson, Branden R., Ueki, Yumi, Reardon, Sara, Karl, Mike O., Georgi, Sean, Hartman, Byron H., Lamba, Deepak A., Reh, Thomas A.
Publicado 2011

A Human Retinal Pigment Epithelium-Based Screening Platform Reveals Inducers of Photoreceptor Outer Segments Phagocytosis

por Schreiter, Sven, Vafia, Katerina, Barsacchi, Rico, Tsang, Stephen H., Bickle, Marc, Ader, Marius, Karl, Mike O., Tanaka, Elly M., Almedawar, Seba
Publicado 2020

MERTK-Dependent Ensheathment of Photoreceptor Outer Segments by Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium

por Almedawar, Seba, Vafia, Katerina, Schreiter, Sven, Neumann, Katrin, Khattak, Shahryar, Kurth, Thomas, Ader, Marius, Karl, Mike O., Tsang, Stephen H., Tanaka, Elly M.
Publicado 2020

The Light Peak of the Electroretinogram Is Dependent on Voltage-gated Calcium Channels and Antagonized by Bestrophin (Best-1)

por Marmorstein, Lihua Y., Wu, Jiang, McLaughlin, Precious, Yocom, John, Karl, Mike O., Neussert, Rudgar, Wimmers, Soenke, Stanton, J. Brett, Gregg, Ronald G., Strauss, Olaf, Peachey, Neal S., Marmorstein, Alan D.
Publicado 2006

Modeling inducible neuropathologies of the retina with differential phenotypes in organoids

por Völkner, Manuela, Wagner, Felix, Kurth, Thomas, Sykes, Alex M., Del Toro Runzer, Claudia, Ebner, Lynn J. A., Kavak, Cagri, Alexaki, Vasileia Ismini, Cimalla, Peter, Mehner, Mirko, Koch, Edmund, Karl, Mike O.
Publicado 2023

Transplanted human cones incorporate into the retina and function in a murine cone degeneration model

por Gasparini, Sylvia J., Tessmer, Karen, Reh, Miriam, Wieneke, Stephanie, Carido, Madalena, Völkner, Manuela, Borsch, Oliver, Swiersy, Anka, Zuzic, Marta, Goureau, Olivier, Kurth, Thomas, Busskamp, Volker, Zeck, Günther, Karl, Mike O., Ader, Marius
Publicado 2022

Reliability of human retina organoid generation from hiPSC-derived neuroepithelial cysts

por Carido, Madalena, Völkner, Manuela, Steinheuer, Lisa Maria, Wagner, Felix, Kurth, Thomas, Dumler, Natalie, Ulusoy, Selen, Wieneke, Stephanie, Norniella, Anabel Villanueva, Golfieri, Cristina, Khattak, Shahryar, Schönfelder, Bruno, Scamozzi, Maria, Zoschke, Katja, Canzler, Sebastian, Hackermüller, Jörg, Ader, Marius, Karl, Mike O.
Publicado 2023

HBEGF-TNF induce a complex outer retinal pathology with photoreceptor cell extrusion in human organoids

por Völkner, Manuela, Wagner, Felix, Steinheuer, Lisa Maria, Carido, Madalena, Kurth, Thomas, Yazbeck, Ali, Schor, Jana, Wieneke, Stephanie, Ebner, Lynn J. A., Del Toro Runzer, Claudia, Taborsky, David, Zoschke, Katja, Vogt, Marlen, Canzler, Sebastian, Hermann, Andreas, Khattak, Shahryar, Hackermüller, Jörg, Karl, Mike O.
Publicado 2022