Napabucasin Drug‐Drug Interaction Potential, Safety, Tolerability, and Pharmacokinetics Following Oral Dosing in Healthy Adult Volunteers

por Dai, Xiaoshu, Karol, Michael D., Hitron, Matthew, Hard, Marjie L., Goulet, Matthew T., McLaughlin, Colleen F., Brantley, Scott J.
Publicado 2021

Mass balance and pharmacokinetics of an oral dose of (14)C‐napabucasin in healthy adult male subjects

por Dai, Xiaoshu, Karol, Michael D., Hitron, Matthew, Hard, Marjie L., Blanchard, John Evan, Eraut, Nicola C. J. E., Rich, Natalie, Gufford, Brandon T.
Publicado 2021

A first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid ma...

por Goldman, Jonathan W, Raju, Robert N, Gordon, Gregory A, El-Hariry, Iman, Teofilivici, Florentina, Vukovic, Vojo M, Bradley, Robert, Karol, Michael D, Chen, Yu, Guo, Wei, Inoue, Takayo, Rosen, Lee S
Publicado 2013