Reproducible preclinical research—Is embracing variability the answer?

por Karp, Natasha A.
Publicado 2018

A Common Control Group - Optimising the Experiment Design to Maximise Sensitivity

por Bate, Simon, Karp, Natasha A.
Publicado 2014

What is the optimum design for my animal experiment?

por Karp, Natasha A, Fry, Derek
Publicado 2021

Statistical simulations show that scientists need not increase overall sample size by default when including both sexes in in vivo studies

por Phillips, Benjamin, Haschler, Timo N., Karp, Natasha A.
Publicado 2023

Robust and Sensitive Analysis of Mouse Knockout Phenotypes

por Karp, Natasha A., Melvin, David, Mott, Richard F.
Publicado 2012

onlineFDR: an R package to control the false discovery rate for growing data repositories

por Robertson, David S, Wildenhain, Jan, Javanmard, Adel, Karp, Natasha A
Publicado 2019

Improving the Identification of Phenotypic Abnormalities and Sexual Dimorphism in Mice When Studying Rare Event Categorical Characteristics

por Karp, Natasha A., Heller, Ruth, Yaacoby, Shay, White, Jacqueline K., Benjamini, Yoav
Publicado 2017

PhenStat: A Tool Kit for Standardized Analysis of High Throughput Phenotypic Data

por Kurbatova, Natalja, Mason, Jeremy C., Morgan, Hugh, Meehan, Terrence F., Karp, Natasha A.
Publicado 2015

Statistical reproducibility for pairwise t-tests in pharmaceutical research

por Simkus, Andrea, Coolen, Frank PA, Coolen-Maturi, Tahani, Karp, Natasha A, Bendtsen, Claus
Publicado 2021

Reporting phenotypes in mouse models when considering body size as a potential confounder

por Oellrich, Anika, Meehan, Terrence F., Parkinson, Helen, Sarntivijai, Sirarat, White, Jacqueline K., Karp, Natasha A.
Publicado 2016

Genome wide in vivo mouse screen data from studies to assess host regulation of metastatic colonisation

por van der Weyden, Louise, Karp, Natasha A., Swiatkowska, Agnieszka, Adams, David J., Speak, Anneliese O.
Publicado 2017

Improving reproducibility in animal research by splitting the study population into several ‘mini-experiments’

por von Kortzfleisch, Vanessa Tabea, Karp, Natasha A., Palme, Rupert, Kaiser, Sylvia, Sachser, Norbert, Richter, S. Helene
Publicado 2020

A multi-batch design to deliver robust estimates of efficacy and reduce animal use – a syngeneic tumour case study

por Karp, Natasha A., Wilson, Zena, Stalker, Eve, Mooney, Lorraine, Lazic, Stanley E., Zhang, Bairu, Hardaker, Elizabeth
Publicado 2020

Optimizing the design of population-based patient-derived tumor xenograft studies to better predict clinical response

por Floc'h, Nicolas, Guerriero, Maria Luisa, Ramos-Montoya, Antonio, Davies, Barry R., Cairns, Jonathan, Karp, Natasha A.
Publicado 2018

A qualitative study of the barriers to using blinding in in vivo experiments and suggestions for improvement

por Karp, Natasha A., Pearl, Esther J., Stringer, Emma J., Barkus, Chris, Ulrichsen, Jane Coates, Percie du Sert, Nathalie
Publicado 2022

Optimising experimental design for high-throughput phenotyping in mice: a case study

por Karp, Natasha A., Baker, Lauren A., Gerdin, Anna-Karin B., Adams, Niels C., Ramírez-Solis, Ramiro, White, Jacqueline K.
Publicado 2010

Impact of Temporal Variation on Design and Analysis of Mouse Knockout Phenotyping Studies

por Karp, Natasha A., Speak, Anneliese O., White, Jacqueline K., Adams, David J., Hrabé de Angelis, Martin, Hérault, Yann, Mott, Richard F.
Publicado 2014

Standardized Welfare Terms for the Zebrafish Community

por Goodwin, Nicola, Karp, Natasha A., Blackledge, Samuel, Clark, Bradley, Keeble, Rosemary, Kovacs, Ceri, Murray, Katrina N., Price, Michael, Thompson, Peter, Bussell, James
Publicado 2016

Sex differences and sex bias in human circadian and sleep physiology research

por Spitschan, Manuel, Santhi, Nayantara, Ahluwalia, Amrita, Fischer, Dorothee, Hunt, Lilian, Karp, Natasha A, Lévi, Francis, Pineda-Torra, Inés, Vidafar, Parisa, White, Rhiannon
Publicado 2022

IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD

por Briend, Emmanuel, Ferguson, G. John, Mori, Michiko, Damera, Gautam, Stephenson, Katherine, Karp, Natasha A., Sethi, Sanjay, Ward, Christine K., Sleeman, Matthew A., Erjefält, Jonas S., Finch, Donna K.
Publicado 2017