Bovine AAV Transcytosis Inhibition by Tannic Acid Results in Functional Expression of CFTR in Vitro and Altered Bio-Distribution in Vivo

por Di Pasquale, Giovanni, Ostedgaard, Lynda, Vermeer, Daniel, Swaim, William D., Karp, Philip, Chiorini, John A.
Publicado 2011

Isoform-Specific Regulation and Localization of the Coxsackie and Adenovirus Receptor in Human Airway Epithelia

por Excoffon, Katherine J. D. A., Gansemer, Nicholas D., Mobily, Matthew E., Karp, Philip H., Parekh, Kalpaj R., Zabner, Joseph
Publicado 2010

Nominal carbonic anhydrase activity minimizes airway‐surface liquid pH changes during breathing

por Thornell, Ian M., Li, Xiaopeng, Tang, Xiao Xiao, Brommel, Christian M., Karp, Philip H., Welsh, Michael J., Zabner, Joseph
Publicado 2018

TNFα and IL-17 alkalinize airway surface liquid through CFTR and pendrin

por Rehman, Tayyab, Thornell, Ian M., Pezzulo, Alejandro A., Thurman, Andrew L., Romano Ibarra, Guillermo S., Karp, Philip H., Tan, Ping, Duffey, Michael E., Welsh, Michael J.
Publicado 2020

WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia

por Rehman, Tayyab, Karp, Philip H., Thurman, Andrew L., Mather, Steven E., Jain, Akansha, Cooney, Ashley L., Sinn, Patrick L., Pezzulo, Alejandro A., Duffey, Michael E., Welsh, Michael J.
Publicado 2022

Integrin α6β4 Identifies Human Distal Lung Epithelial Progenitor Cells with Potential as a Cell-Based Therapy for Cystic Fibrosis Lung Disease

por Li, Xiaopeng, Rossen, Nathan, Sinn, Patrick L., Hornick, Andrew L., Steines, Benjamin R., Karp, Philip H., Ernst, Sarah E., Adam, Ryan J., Moninger, Thomas O., Levasseur, Dana N., Zabner, Joseph
Publicado 2013

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract

por Ortiz, Miguel E., Thurman, Andrew, Pezzulo, Alejandro A., Leidinger, Mariah R., Klesney-Tait, Julia A., Karp, Philip H., Tan, Ping, Wohlford-Lenane, Christine, McCray, Paul B., Meyerholz, David K.
Publicado 2020

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract

por Ortiz Bezara, Miguel E., Thurman, Andrew, Pezzulo, Alejandro A., Leidinger, Mariah R., Klesney-Tait, Julia A., Karp, Philip H., Tan, Ping, Wohlford-Lenane, Christine, McCray, Paul B., Meyerholz, David K.
Publicado 2020

Small molecule ion channels increase host defenses in cystic fibrosis airway epithelia

por Muraglia, Katrina A., Chorghade, Rajeev S., Kim, Bo Ram, Tang, Xiao Xiao, Shah, Viral S., Grillo, Anthony S., Daniels, Page N., Cioffi, Alexander G., Karp, Philip H., Zhu, Lingyang, Welsh, Michael J., Burke, Martin D.
Publicado 2019

CFTR-rich ionocytes mediate chloride absorption across airway epithelia

por Lei, Lei, Traore, Soumba, Romano Ibarra, Guillermo S., Karp, Philip H., Rehman, Tayyab, Meyerholz, David K., Zabner, Joseph, Stoltz, David A., Sinn, Patrick L., Welsh, Michael J., McCray, Paul B., Thornell, Ian M.
Publicado 2023

Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling

por Mao, Suifang, Shah, Alok S., Moninger, Thomas O., Ostedgaard, Lynda S., Lu, Lin, Tang, Xiao Xiao, Thornell, Ian M., Reznikov, Leah R., Ernst, Sarah E., Karp, Philip H., Tan, Ping, Keshavjee, Shaf, Abou Alaiwa, Mahmoud H., Welsh, Michael J.
Publicado 2018

Sinus Hypoplasia Precedes Sinus Infection in a Porcine Model of Cystic Fibrosis

por Chang, Eugene H, Pezzulo, Alejandro A, Meyerholz, David K, Potash, Andrea E, Wallen, Tanner J, Reznikov, Leah R, Sieren, Jessica C, Karp, Philip H, Ernst, Sarah, Moninger, Thomas O, Gansemer, Nicholas D, McCray, Paul B, Stoltz, David A, Welsh, Michael J, Zabner, Joseph
Publicado 2012

Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs

por Meyerholz, David K., Stoltz, David A., Gansemer, Nick D., Ernst, Sarah E., Cook, Daniel P., Strub, Matthew D., LeClair, Erica N., Barker, Carrie K., Adam, Ryan J., Leidinger, Mariah R., Gibson-Corley, Katherine N., Karp, Philip H., Welsh, Michael J., McCray, Paul B.
Publicado 2018

Multicenter Intestinal Current Measurements in Rectal Biopsies from CF and Non-CF Subjects to Monitor CFTR Function

por Clancy, John P., Szczesniak, Rhonda D., Ashlock, Melissa A., Ernst, Sarah E., Fan, Lijuan, Hornick, Douglas B., Karp, Philip H., Khan, Umer, Lymp, James, Ostmann, Alicia J., Rezayat, Amir, Starner, Timothy D., Sugandha, Shajan P., Sun, Hongtao, Quinney, Nancy, Donaldson, Scott H., Rowe, Steven M., Gabriel, Sherif E.
Publicado 2013