LiverQuant: An Improved Method for Quantitative Analysis of Liver Pathology

por Hellen, Dominick J., Karpen, Saul J.
Publicado 2023

Features of Cirrhotic Cardiomyopathy Early in the Lives of Infants With Biliary Atresia Correlate With Outcomes Following Kasai Portoenterostomy

por Morrison, Jhavene, Ferguson, Eric, Figueroa, Janet, Karpen, Saul J.
Publicado 2022

Endotoxin leads to rapid subcellular re-localization of hepatic RXRα: A novel mechanism for reduced hepatic gene expression in inflammation

por Ghose, Romi, Zimmerman, Tracy L, Thevananther, Sundararajah, Karpen, Saul J
Publicado 2004

Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives

por Arab, Juan P., Karpen, Saul J., Dawson, Paul A., Arrese, Marco, Trauner, Michael
Publicado 2016

Attenuation of the Hepatoprotective Effects of Ileal Apical Sodium Dependent Bile Acid Transporter (ASBT) Inhibition in Choline-Deficient L-Amino Acid-Defined (CDAA) Diet-Fed Mice

por Rao, Anuradha, van de Peppel, Ivo P., Gumber, Sanjeev, Karpen, Saul J., Dawson, Paul A.
Publicado 2020

Surgical and Medical Aspects of the Initial Treatment of Biliary Atresia: Position Paper

por Davenport, Mark, Madadi-Sanjani, Omid, Chardot, Christophe, Verkade, Henkjan J., Karpen, Saul J., Petersen, Claus
Publicado 2022

Sexually Dimorphic Genome-Wide Binding of Retinoid X Receptor alpha (RXRα) Determines Male-Female Differences in the Expression of Hepatic Lipid Processing Genes in Mice

por Kosters, Astrid, Sun, Deqiang, Wu, Hao, Tian, Feng, Felix, Julio C., Li, Wei, Karpen, Saul J.
Publicado 2013

Loss of zebrafish pkd1l1 causes biliary defects that have implications for biliary atresia splenic malformation

por Ali, Rouknuddin Q., Meyer-Miner, Anne, David-Rachel, Marie, Lee, Fiona J. H., Wilkins, Benjamin J., Karpen, Saul J., Ciruna, Brian, Ghanekar, Anand, Kamath, Binita M.
Publicado 2023

Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice

por Truong, Jennifer K., Li, Jianing, Li, Qin, Pachura, Kimberly, Rao, Anuradha, Gumber, Sanjeev, Fuchs, Claudia Daniela, Feranchak, Andrew P., Karpen, Saul J., Trauner, Michael, Dawson, Paul A.
Publicado 2023

Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury

por Truong, Jennifer K., Bennett, Ashley L., Klindt, Caroline, Donepudi, Ajay C., Malla, Sudarshan R., Pachura, Kimberly J., Zaufel, Alex, Moustafa, Tarek, Dawson, Paul A., Karpen, Saul J.
Publicado 2022

The Beneficial Effects of Apical Sodium‐Dependent Bile Acid Transporter Inactivation Depend on Dietary Fat Composition

por van de Peppel, Ivo P., Rao, Anuradha, Dommerholt, Marleen B., Bongiovanni, Laura, Thomas, Rachel, de Bruin, Alain, Karpen, Saul J., Dawson, Paul A., Verkade, Henkjan J., Jonker, Johan W.
Publicado 2020

Elevated bile acids are associated with left ventricular structural changes in biliary atresia

por Virk, Manpreet K., Mian, Muhammad Umair M., Bashir, Dalia A., Wilkes, John K., Schlingman, Tobias, Flores, Saul, Kennedy, Curtis, Lam, Fong, Arikan, Ayse A., Nguyen, Trung, Mysore, Krupa, Galvan, Nhu Thao Nguyen, Coss-Bu, Jorge, Karpen, Saul J., Harpavat, Sanjiv, Desai, Moreshwar S.
Publicado 2023

Correlation of Immune Markers With Outcomes in Biliary Atresia Following Intravenous Immunoglobulin Therapy

por Kim, Sehee, Moore, Jeffrey, Alonso, Estella, Bednarek, Joseph, Bezerra, Jorge A., Goodhue, Catherine, Karpen, Saul J., Loomes, Kathleen M., Magee, John C., Ng, Vicky L., Sherker, Averell H., Smith, Caroline, Spino, Cathie, Venkat, Veena, Wang, Kasper, Sokol, Ronald J., Mack, Cara L.
Publicado 2019

Use of funded multicenter prospective longitudinal databases to inform clinical trials in rare diseases—Examination of cholestatic liver disease in Alagille syndrome

por Shneider, Benjamin L., Kamath, Binita M., Magee, John C., Goodrich, Nathan P., Loomes, Kathleen M., Ye, Wen, Spino, Cathie, Alonso, Estella M., Molleston, Jean P., Bezerra, Jorge A., Wang, Kasper S., Karpen, Saul J., Horslen, Simon P., Guthery, Stephen L., Rosenthal, Philip, Squires, Robert H., Sokol, Ronald J.
Publicado 2022

Neurodevelopmental Outcomes in Children With Inherited Liver Disease and Native Liver

por Leung, Daniel H., Sorensen, Lisa G., Ye, Wen, Hawthorne, Kieran, Ng, Vicky L., Loomes, Kathleen M., Fredericks, Emily M., Alonso, Estella M., Heubi, James E., Horslen, Simon P., Karpen, Saul J., Molleston, Jean P., Rosenthal, Philip, Sokol, Ronald J., Squires, Robert H., Wang, Kasper S., Kamath, Binita M., Magee, John C.
Publicado 2022

Randomized placebo‐controlled trial of losartan for pediatric NAFLD

por Vos, Miriam B., Van Natta, Mark L., Blondet, Niviann M., Dasarathy, Srinivasan, Fishbein, Mark, Hertel, Paula, Jain, Ajay K., Karpen, Saul J., Lavine, Joel E., Mohammad, Saeed, Miriel, Laura A., Molleston, Jean P., Mouzaki, Marialena, Sanyal, Arun, Sharkey, Emily P., Schwimmer, Jeffrey B., Tonascia, James, Wilson, Laura A., Xanthakos, Stavra A.
Publicado 2022

Placebo‐Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome

por Shneider, Benjamin L., Spino, Cathie, Kamath, Binita M., Magee, John C., Bass, Lee M., Setchell, Kenneth D., Miethke, Alexander, Molleston, Jean P., Mack, Cara L., Squires, Robert H., Murray, Karen F., Loomes, Kathleen M., Rosenthal, Philip, Karpen, Saul J., Leung, Daniel H., Guthery, Stephen L., Thomas, Danny, Sherker, Averell H., Sokol, Ronald J.
Publicado 2018

Unraveling the Relationship Between Itching, Scratch Scales, and Biomarkers in Children With Alagille Syndrome

por Kamath, Binita M., Spino, Cathie, McLain, Richard, Magee, John C., Fredericks, Emily M., Setchell, Kenneth D., Miethke, Alexander, Molleston, Jean P., Mack, Cara L., Squires, Robert H., Alonso, Estella M., Murray, Karen F., Loomes, Kathleen M., Kyle Jensen, M., Karpen, Saul J., Rosenthal, Philip, Thomas, Danny, Sokol, Ronald J., Shneider, Benjamin L.
Publicado 2020

Initial assessment of the infant with neonatal cholestasis—Is this biliary atresia?

por Shneider, Benjamin L., Moore, Jeff, Kerkar, Nanda, Magee, John C., Ye, Wen, Karpen, Saul J., Kamath, Binita M., Molleston, Jean P., Bezerra, Jorge A., Murray, Karen F., Loomes, Kathleen M., Whitington, Peter F., Rosenthal, Philip, Squires, Robert H., Guthery, Stephen L., Arnon, Ronen, Schwarz, Kathleen B., Turmelle, Yumirle P., Sherker, Averell H., Sokol, Ronald J.
Publicado 2017

Modeling Outcomes in Children With Biliary Atresia With Native Liver After 2 Years of Age

por Venkat, Veena, Ng, Vicky L., Magee, John C., Ye, Wen, Hawthorne, Kieran, Harpavat, Sanjiv, Molleston, Jean P., Murray, Karen F., Wang, Kasper S., Soufi, Nisreen, Bass, Lee M., Alonso, Estella M., Bezerra, Jorge A., Jensen, M. Kyle, Kamath, Binita M., Loomes, Kathleen M., Mack, Cara L., Rosenthal, Philip, Shneider, Benjamin L., Squires, Robert H., Sokol, Ronald J., Karpen, Saul J.
Publicado 2020