CollapsABEL: an R library for detecting compound heterozygote alleles in genome-wide association studies

por Zhong, Kaiyin, Karssen, Lennart C., Kayser, Manfred, Liu, Fan
Publicado 2016

The GenABEL Project for statistical genomics

por Karssen, Lennart C., van Duijn, Cornelia M., Aulchenko, Yurii S.
Publicado 2016

PheLiGe: an interactive database of billions of human genotype–phenotype associations

por Shashkova, Tatiana I, Pakhomov, Eugene D, Gorev, Denis D, Karssen, Lennart C, Joshi, Peter K, Aulchenko, Yurii S
Publicado 2020

Non-additive genome-wide association scan reveals a new gene associated with habitual coffee consumption

por Pirastu, Nicola, Kooyman, Maarten, Robino, Antonietta, van der Spek, Ashley, Navarini, Luciano, Amin, Najaf, Karssen, Lennart C., Van Duijn, Cornelia M, Gasparini, Paolo
Publicado 2016

Development and Replication of a Genome-Wide Polygenic Risk Score for Chronic Back Pain

por Tsepilov, Yakov A., Elgaeva, Elizaveta E., Nostaeva, Arina V., Compte, Roger, Kuznetsov, Ivan A., Karssen, Lennart C., Freidin, Maxim B., Suri, Pradeep, Williams, Frances M. K., Aulchenko, Yurii S.
Publicado 2023

Association Analysis of Bitter Receptor Genes in Five Isolated Populations Identifies a Significant Correlation between TAS2R43 Variants and Coffee Liking

por Pirastu, Nicola, Kooyman, Maarten, Traglia, Michela, Robino, Antonietta, Willems, Sara M., Pistis, Giorgio, d’Adamo, Pio, Amin, Najaf, d’Eustacchio, Angela, Navarini, Luciano, Sala, Cinzia, Karssen, Lennart C., van Duijn, Cornelia, Toniolo, Daniela, Gasparini, Paolo
Publicado 2014

Insight in Genome-Wide Association of Metabolite Quantitative Traits by Exome Sequence Analyses

por Demirkan, Ayşe, Henneman, Peter, Verhoeven, Aswin, Dharuri, Harish, Amin, Najaf, van Klinken, Jan Bert, Karssen, Lennart C., de Vries, Boukje, Meissner, Axel, Göraler, Sibel, van den Maagdenberg, Arn M. J. M., Deelder, André M., C ’t Hoen, Peter A., van Duijn, Cornelia M., van Dijk, Ko Willems
Publicado 2015

‘Omics’ biomarkers associated with chronic low back pain: protocol of a retrospective longitudinal study

por Allegri, Massimo, De Gregori, Manuela, Minella, Cristina E, Klersy, Catherine, Wang, Wei, Sim, Moira, Gieger, Christian, Manz, Judith, Pemberton, Iain K, MacDougall, Jane, Williams, Frances MK, Van Zundert, Jan, Buyse, Klaas, Lauc, Gordan, Gudelj, Ivan, Primorac, Dragan, Skelin, Andrea, Aulchenko, Yurii S, Karssen, Lennart C, Kapural, Leonardo, Rauck, Richard, Fanelli, Guido
Publicado 2016

Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes

por Rivera, Natalia V, Carreras-Torres, Robert, Roncarati, Roberta, Viviani-Anselmi, Chiara, De Micco, Francesca, Mezzelani, Alessandra, Koch, Werner, Hoppmann, Petra, Kastrati, Adnan, Stewart, Alexandre FR, Chen, Li, Roberts, Robert, Karssen, Lennart C, Amin, Najaf, Trimarco, Valentina, Izzo, Raffaele, Iaccarino, Guido, Condorelli, Gerolama, Puca, Annibale A, Pagnotta, Paolo, Airoldi, Flavio, Trimarco, Bruno, van Duijn, Cornelia M, Condorelli, Gianluigi, Briguori, Carlo
Publicado 2013

Improved imputation quality of low-frequency and rare variants in European samples using the ‘Genome of The Netherlands'

por Deelen, Patrick, Menelaou, Androniki, van Leeuwen, Elisabeth M, Kanterakis, Alexandros, van Dijk, Freerk, Medina-Gomez, Carolina, Francioli, Laurent C, Hottenga, Jouke Jan, Karssen, Lennart C, Estrada, Karol, Kreiner-Møller, Eskil, Rivadeneira, Fernando, van Setten, Jessica, Gutierrez-Achury, Javier, Westra, Harm-Jan, Franke, Lude, van Enckevort, David, Dijkstra, Martijn, Byelas, Heorhiy, van Duijn, Cornelia M, de Bakker, Paul I W, Wijmenga, Cisca, Swertz, Morris A
Publicado 2014

The Challenges of Genome-Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels

por van Leeuwen, Elisabeth M., Smouter, Françoise A. S., Kam-Thong, Tony, Karbalai, Nazanin, Smith, Albert V., Harris, Tamara B., Launer, Lenore J., Sitlani, Colleen M., Li, Guo, Brody, Jennifer A., Bis, Joshua C., White, Charles C., Jaiswal, Alok, Oostra, Ben A., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, Andre G., Boerwinkle, Eric, Ballantyne, Christie M., Gudnason, Vilmundur, Psaty, Bruce M., Cupples, L. Adrienne, Järvelin, Marjo-Riitta, Ripatti, Samuli, Isaacs, Aaron, Müller-Myhsok, Bertram, Karssen, Lennart C., van Duijn, Cornelia M.
Publicado 2014

Characteristics of de novo structural changes in the human genome

por Kloosterman, Wigard P., Francioli, Laurent C., Hormozdiari, Fereydoun, Marschall, Tobias, Hehir-Kwa, Jayne Y., Abdellaoui, Abdel, Lameijer, Eric-Wubbo, Moed, Matthijs H., Koval, Vyacheslav, Renkens, Ivo, van Roosmalen, Markus J., Arp, Pascal, Karssen, Lennart C., Coe, Bradley P., Handsaker, Robert E., Suchiman, Eka D., Cuppen, Edwin, Thung, Djie Tjwan, McVey, Mitch, Wendl, Michael C., Uitterlinden, André, van Duijn, Cornelia M., Swertz, Morris A., Wijmenga, Cisca, van Ommen, GertJan B., Slagboom, P. Eline, Boomsma, Dorret I., Schönhuth, Alexander, Eichler, Evan E., de Bakker, Paul I.W., Ye, Kai, Guryev, Victor
Publicado 2015

Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations

por Demirkan, Ayşe, van Duijn, Cornelia M., Ugocsai, Peter, Isaacs, Aaron, Pramstaller, Peter P., Liebisch, Gerhard, Wilson, James F., Johansson, Åsa, Rudan, Igor, Aulchenko, Yurii S., Kirichenko, Anatoly V., Janssens, A. Cecile J. W., Jansen, Ritsert C., Gnewuch, Carsten, Domingues, Francisco S., Pattaro, Cristian, Wild, Sarah H., Jonasson, Inger, Polasek, Ozren, Zorkoltseva, Irina V., Hofman, Albert, Karssen, Lennart C., Struchalin, Maksim, Floyd, James, Igl, Wilmar, Biloglav, Zrinka, Broer, Linda, Pfeufer, Arne, Pichler, Irene, Campbell, Susan, Zaboli, Ghazal, Kolcic, Ivana, Rivadeneira, Fernando, Huffman, Jennifer, Hastie, Nicholas D., Uitterlinden, Andre, Franke, Lude, Franklin, Christopher S., Vitart, Veronique, Nelson, Christopher P., Preuss, Michael, Bis, Joshua C., O'Donnell, Christopher J., Franceschini, Nora, Witteman, Jacqueline C. M., Axenovich, Tatiana, Oostra, Ben A., Meitinger, Thomas, Hicks, Andrew A., Hayward, Caroline, Wright, Alan F., Gyllensten, Ulf, Campbell, Harry, Schmitz, Gerd
Publicado 2012

Genome-Wide Meta-Analysis of Myopia and Hyperopia Provides Evidence for Replication of 11 Loci

por Simpson, Claire L., Wojciechowski, Robert, Oexle, Konrad, Murgia, Federico, Portas, Laura, Li, Xiaohui, Verhoeven, Virginie J. M., Vitart, Veronique, Schache, Maria, Hosseini, S. Mohsen, Hysi, Pirro G., Raffel, Leslie J., Cotch, Mary Frances, Chew, Emily, Klein, Barbara E. K., Klein, Ronald, Wong, Tien Yin, van Duijn, Cornelia M., Mitchell, Paul, Saw, Seang Mei, Fossarello, Maurizio, Wang, Jie Jin, Polašek, Ozren, Campbell, Harry, Rudan, Igor, Oostra, Ben A., Uitterlinden, André G., Hofman, Albert, Rivadeneira, Fernando, Amin, Najaf, Karssen, Lennart C., Vingerling, Johannes R., Döring, Angela, Bettecken, Thomas, Bencic, Goran, Gieger, Christian, Wichmann, H.-Erich, Wilson, James F., Venturini, Cristina, Fleck, Brian, Cumberland, Phillippa M., Rahi, Jugnoo S., Hammond, Chris J., Hayward, Caroline, Wright, Alan F., Paterson, Andrew D., Baird, Paul N., Klaver, Caroline C. W., Rotter, Jerome I., Pirastu, Mario, Meitinger, Thomas, Bailey-Wilson, Joan E., Stambolian, Dwight
Publicado 2014

The Genome of the Netherlands: design, and project goals

por Boomsma, Dorret I, Wijmenga, Cisca, Slagboom, Eline P, Swertz, Morris A, Karssen, Lennart C, Abdellaoui, Abdel, Ye, Kai, Guryev, Victor, Vermaat, Martijn, van Dijk, Freerk, Francioli, Laurent C, Hottenga, Jouke Jan, Laros, Jeroen F J, Li, Qibin, Li, Yingrui, Cao, Hongzhi, Chen, Ruoyan, Du, Yuanping, Li, Ning, Cao, Sujie, van Setten, Jessica, Menelaou, Androniki, Pulit, Sara L, Hehir-Kwa, Jayne Y, Beekman, Marian, Elbers, Clara C, Byelas, Heorhiy, de Craen, Anton J M, Deelen, Patrick, Dijkstra, Martijn, den Dunnen, Johan T, de Knijff, Peter, Houwing-Duistermaat, Jeanine, Koval, Vyacheslav, Estrada, Karol, Hofman, Albert, Kanterakis, Alexandros, Enckevort, David van, Mai, Hailiang, Kattenberg, Mathijs, van Leeuwen, Elisabeth M, Neerincx, Pieter B T, Oostra, Ben, Rivadeneira, Fernanodo, Suchiman, Eka H D, Uitterlinden, Andre G, Willemsen, Gonneke, Wolffenbuttel, Bruce H, Wang, Jun, de Bakker, Paul I W, van Ommen, Gert-Jan, van Duijn, Cornelia M
Publicado 2014

A Genome-Wide Screen for Interactions Reveals a New Locus on 4p15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol

por Surakka, Ida, Isaacs, Aaron, Karssen, Lennart C., Laurila, Pirkka-Pekka P., Middelberg, Rita P. S., Tikkanen, Emmi, Ried, Janina S., Lamina, Claudia, Mangino, Massimo, Igl, Wilmar, Hottenga, Jouke-Jan, Lagou, Vasiliki, van der Harst, Pim, Mateo Leach, Irene, Esko, Tõnu, Kutalik, Zoltán, Wainwright, Nicholas W., Struchalin, Maksim V., Sarin, Antti-Pekka, Kangas, Antti J., Viikari, Jorma S., Perola, Markus, Rantanen, Taina, Petersen, Ann-Kristin, Soininen, Pasi, Johansson, Åsa, Soranzo, Nicole, Heath, Andrew C., Papamarkou, Theodore, Prokopenko, Inga, Tönjes, Anke, Kronenberg, Florian, Döring, Angela, Rivadeneira, Fernando, Montgomery, Grant W., Whitfield, John B., Kähönen, Mika, Lehtimäki, Terho, Freimer, Nelson B., Willemsen, Gonneke, de Geus, Eco J. C., Palotie, Aarno, Sandhu, Manj S., Waterworth, Dawn M., Metspalu, Andres, Stumvoll, Michael, Uitterlinden, André G., Jula, Antti, Navis, Gerjan, Wijmenga, Cisca, Wolffenbuttel, Bruce H. R., Taskinen, Marja-Riitta, Ala-Korpela, Mika, Kaprio, Jaakko, Kyvik, Kirsten O., Boomsma, Dorret I., Pedersen, Nancy L., Gyllensten, Ulf, Wilson, James F., Rudan, Igor, Campbell, Harry, Pramstaller, Peter P., Spector, Tim D., Witteman, Jacqueline C. M., Eriksson, Johan G., Salomaa, Veikko, Oostra, Ben A., Raitakari, Olli T., Wichmann, H.-Erich, Gieger, Christian, Järvelin, Marjo-Riitta, Martin, Nicholas G., Hofman, Albert, McCarthy, Mark I., Peltonen, Leena, van Duijn, Cornelia M., Aulchenko, Yurii S., Ripatti, Samuli
Publicado 2011

Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

por van Leeuwen, Elisabeth M., Karssen, Lennart C., Deelen, Joris, Isaacs, Aaron, Medina-Gomez, Carolina, Mbarek, Hamdi, Kanterakis, Alexandros, Trompet, Stella, Postmus, Iris, Verweij, Niek, van Enckevort, David J., Huffman, Jennifer E., White, Charles C., Feitosa, Mary F., Bartz, Traci M., Manichaikul, Ani, Joshi, Peter K., Peloso, Gina M., Deelen, Patrick, van Dijk, Freerk, Willemsen, Gonneke, de Geus, Eco J., Milaneschi, Yuri, Penninx, Brenda W.J.H., Francioli, Laurent C., Menelaou, Androniki, Pulit, Sara L., Rivadeneira, Fernando, Hofman, Albert, Oostra, Ben A., Franco, Oscar H., Leach, Irene Mateo, Beekman, Marian, de Craen, Anton J.M., Uh, Hae-Won, Trochet, Holly, Hocking, Lynne J., Porteous, David J., Sattar, Naveed, Packard, Chris J., Buckley, Brendan M., Brody, Jennifer A., Bis, Joshua C., Rotter, Jerome I., Mychaleckyj, Josyf C., Campbell, Harry, Duan, Qing, Lange, Leslie A., Wilson, James F., Hayward, Caroline, Polasek, Ozren, Vitart, Veronique, Rudan, Igor, Wright, Alan F., Rich, Stephen S., Psaty, Bruce M., Borecki, Ingrid B., Kearney, Patricia M., Stott, David J., Adrienne Cupples, L., Jukema, J. Wouter, van der Harst, Pim, Sijbrands, Eric J., Hottenga, Jouke-Jan, Uitterlinden, Andre G., Swertz, Morris A., van Ommen, Gert-Jan B., de Bakker, Paul I.W., Eline Slagboom, P., Boomsma, Dorret I., Wijmenga, Cisca, van Duijn, Cornelia M.
Publicado 2015

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

por Horikoshi, Momoko, Mӓgi, Reedik, van de Bunt, Martijn, Surakka, Ida, Sarin, Antti-Pekka, Mahajan, Anubha, Marullo, Letizia, Thorleifsson, Gudmar, Hӓgg, Sara, Hottenga, Jouke-Jan, Ladenvall, Claes, Ried, Janina S., Winkler, Thomas W., Willems, Sara M., Pervjakova, Natalia, Esko, Tõnu, Beekman, Marian, Nelson, Christopher P., Willenborg, Christina, Wiltshire, Steven, Ferreira, Teresa, Fernandez, Juan, Gaulton, Kyle J., Steinthorsdottir, Valgerdur, Hamsten, Anders, Magnusson, Patrik K. E., Willemsen, Gonneke, Milaneschi, Yuri, Robertson, Neil R., Groves, Christopher J., Bennett, Amanda J., Lehtimӓki, Terho, Viikari, Jorma S., Rung, Johan, Lyssenko, Valeriya, Perola, Markus, Heid, Iris M., Herder, Christian, Grallert, Harald, Müller-Nurasyid, Martina, Roden, Michael, Hypponen, Elina, Isaacs, Aaron, van Leeuwen, Elisabeth M., Karssen, Lennart C., Mihailov, Evelin, Houwing-Duistermaat, Jeanine J., de Craen, Anton J. M., Deelen, Joris, Havulinna, Aki S., Blades, Matthew, Hengstenberg, Christian, Erdmann, Jeanette, Schunkert, Heribert, Kaprio, Jaakko, Tobin, Martin D., Samani, Nilesh J., Lind, Lars, Salomaa, Veikko, Lindgren, Cecilia M., Slagboom, P. Eline, Metspalu, Andres, van Duijn, Cornelia M., Eriksson, Johan G., Peters, Annette, Gieger, Christian, Jula, Antti, Groop, Leif, Raitakari, Olli T., Power, Chris, Penninx, Brenda W. J. H., de Geus, Eco, Smit, Johannes H., Boomsma, Dorret I., Pedersen, Nancy L., Ingelsson, Erik, Thorsteinsdottir, Unnur, Stefansson, Kari, Ripatti, Samuli, Prokopenko, Inga, McCarthy, Mark I., Morris, Andrew P.
Publicado 2015

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

por Springelkamp, Henriët., Höhn, René, Mishra, Aniket, Hysi, Pirro G., Khor, Chiea-Chuen, Loomis, Stephanie J., Bailey, Jessica N. Cooke, Gibson, Jane, Thorleifsson, Gudmar, Janssen, Sarah F., Luo, Xiaoyan, Ramdas, Wishal D., Vithana, Eranga, Nongpiur, Monisha E., Montgomery, Grant W., Xu, Liang, Mountain, Jenny E., Gharahkhani, Puya, Lu, Yi, Amin, Najaf, Karssen, Lennart C., Sim, Kar-Seng, van Leeuwen, Elisabeth M., Iglesias, Adriana I., Verhoeven, Virginie J. M., Hauser, Michael A., Loon, Seng-Chee, Despriet, Dominiek D. G., Nag, Abhishek, Venturini, Cristina, Sanfilippo, Paul G., Schillert, Arne, Kang, Jae H., Landers, John, Jonasson, Fridbert, Cree, Angela J., van Koolwijk, Leonieke M. E., Rivadeneira, Fernando, Souzeau, Emmanuelle, Jonsson, Vesteinn, Menon, Geeta, Weinreb, Robert N., de Jong, Paulus T. V. M., Oostra, Ben A., Uitterlinden, André G., Hofman, Albert, Ennis, Sarah, Thorsteinsdottir, Unnur, Burdon, Kathryn P., Spector, Timothy D., Mirshahi, Alireza, Saw, Seang-Mei, Vingerling, Johannes R., Teo, Yik-Ying, Haines, Jonathan L., Wolfs, Roger C. W., Lemij, Hans G., Tai, E-Shyong, Jansonius, Nomdo M., Jonas, Jost B., Cheng, Ching-Yu, Aung, Tin, Viswanathan, Ananth C., Klaver, Caroline C. W., Craig, Jamie E., Macgregor, Stuart, Mackey, David A., Lotery, Andrew J., Stefansson, Kari, Bergen, Arthur A. B., Young, Terri L., Wiggs, Janey L., Pfeiffer, Norbert, Wong, Tien-Yin, Pasquale, Louis R., Hewitt, Alex W., van Duijn, Cornelia M., Hammond, Christopher J.
Publicado 2014

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

por Verhoeven, Virginie J. M., Hysi, Pirro G., Saw, Seang-Mei, Vitart, Veronique, Mirshahi, Alireza, Guggenheim, Jeremy A., Cotch, Mary Frances, Yamashiro, Kenji, Baird, Paul N., Mackey, David A., Wojciechowski, Robert, Ikram, M. Kamran, Hewitt, Alex W., Duggal, Priya, Janmahasatian, Sarayut, Khor, Chiea-Chuen, Fan, Qiao, Zhou, Xin, Young, Terri L., Tai, E-Shyong, Goh, Liang-Kee, Li, Yi-Ju, Aung, Tin, Vithana, Eranga, Teo, Yik-Ying, Tay, Wanting, Sim, Xueling, Rudan, Igor, Hayward, Caroline, Wright, Alan F., Polasek, Ozren, Campbell, Harry, Wilson, James F., Fleck, Brian W., Nakata, Isao, Yoshimura, Nagahisa, Yamada, Ryo, Matsuda, Fumihiko, Ohno-Matsui, Kyoko, Nag, Abhishek, McMahon, George, Pourcain, Beate St., Lu, Yi, Rahi, Jugnoo S., Cumberland, Phillippa M., Bhattacharya, Shomi, Simpson, Claire L., Atwood, Larry D., Li, Xiaohui, Raffel, Leslie J., Murgia, Federico, Portas, Laura, Despriet, Dominiek D. G., van Koolwijk, Leonieke M. E., Wolfram, Christian, Lackner, Karl J., Tönjes, Anke, Mägi, Reedik, Lehtimäki, Terho, Kähönen, Mika, Esko, Tõnu, Metspalu, Andres, Rantanen, Taina, Pärssinen, Olavi, Klein, Barbara E., Meitinger, Thomas, Spector, Timothy D., Oostra, Ben A., Smith, Albert V., de Jong, Paulus T. V. M., Hofman, Albert, Amin, Najaf, Karssen, Lennart C., Rivadeneira, Fernando, Vingerling, Johannes R., Eiríksdóttir, Guðný, Gudnason, Vilmundur, Döring, Angela, Bettecken, Thomas, Uitterlinden, André G., Williams, Cathy, Zeller, Tanja, Castagné, Raphaële, Oexle, Konrad, van Duijn, Cornelia M., Iyengar, Sudha K., Mitchell, Paul, Wang, Jie Jin, Höhn, René, Pfeiffer, Norbert, Bailey-Wilson, Joan E., Stambolian, Dwight, Wong, Tien-Yin, Hammond, Christopher J., Klaver, Caroline C. W.
Publicado 2012