The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection

por Moskovskich, Anna, Goldmann, Ulrich, Kartnig, Felix, Lindinger, Sabrina, Konecka, Justyna, Fiume, Giuseppe, Girardi, Enrico, Superti-Furga, Giulio
Publicado 2019

Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis

por Bensimon, Ariel, Pizzagalli, Mattia D., Kartnig, Felix, Dvorak, Vojtech, Essletzbichler, Patrick, Winter, Georg E., Superti-Furga, Giulio
Publicado 2020

Metabolic drug survey highlights cancer cell dependencies and vulnerabilities

por Pemovska, Tea, Bigenzahn, Johannes W., Srndic, Ismet, Lercher, Alexander, Bergthaler, Andreas, César-Razquin, Adrián, Kartnig, Felix, Kornauth, Christoph, Valent, Peter, Staber, Philipp B., Superti-Furga, Giulio
Publicado 2021

The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification

por Sedlyarov, Vitaly, Eichner, Ruth, Girardi, Enrico, Essletzbichler, Patrick, Goldmann, Ulrich, Nunes-Hasler, Paula, Srndic, Ismet, Moskovskich, Anna, Heinz, Leonhard X., Kartnig, Felix, Bigenzahn, Johannes W., Rebsamen, Manuele, Kovarik, Pavel, Demaurex, Nicolas, Superti-Furga, Giulio
Publicado 2018

Reactogenicity and immunogenicity of the second COVID-19 vaccination in patients with inborn errors of immunity or mannan-binding lectin deficiency

por Göschl, Lisa, Mrak, Daniel, Grabmeier-Pfistershammer, Katharina, Stiasny, Karin, Haslacher, Helmuth, Schneider, Lisa, Deimel, Thomas, Kartnig, Felix, Tobudic, Selma, Aletaha, Daniel, Burgmann, Heinz, Bonelli, Michael, Pickl, Winfried F., Förster-Waldl, Elisabeth, Scheinecker, Clemens, Vossen, Matthias Gerhard
Publicado 2022

A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity

por Boeszoermenyi, Andras, Bernaleau, Léa, Chen, Xudong, Kartnig, Felix, Xie, Min, Zhang, Haobo, Zhang, Sensen, Delacrétaz, Maeva, Koren, Anna, Hopp, Ann-Katrin, Dvorak, Vojtech, Kubicek, Stefan, Aletaha, Daniel, Yang, Maojun, Rebsamen, Manuele, Heinz, Leonhard X., Superti-Furga, Giulio
Publicado 2023

mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation

por Karonitsch, Thomas, Kandasamy, Richard K., Kartnig, Felix, Herdy, Barbara, Dalwigk, Karolina, Niederreiter, Birgit, Holinka, Johannes, Sevelda, Florian, Windhager, Reinhard, Bilban, Martin, Weichhart, Thomas, Säemann, Marcus, Pap, Thomas, Steiner, Günter, Smolen, Josef S., Kiener, Hans P., Superti-Furga, Giulio
Publicado 2018

Accelerated waning of immune responses to a third COVID-19 vaccination in patients with immune-mediated inflammatory diseases

por Mrak, Daniel, Kartnig, Felix, Sieghart, Daniela, Simader, Elisabeth, Radner, Helga, Mandl, Peter, Göschl, Lisa, Hofer, Philipp, Deimel, Thomas, Gessl, Irina, Kain, Renate, Winkler, Stefan, Smolen, Josef S., Perkmann, Thomas, Haslacher, Helmuth, Aletaha, Daniel, Heinz, Leonhard X., Bonelli, Michael
Publicado 2023

Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import

por Girardi, Enrico, Agrimi, Gennaro, Goldmann, Ulrich, Fiume, Giuseppe, Lindinger, Sabrina, Sedlyarov, Vitaly, Srndic, Ismet, Gürtl, Bettina, Agerer, Benedikt, Kartnig, Felix, Scarcia, Pasquale, Noia, Maria Antonietta Di, Liñeiro, Eva, Rebsamen, Manuele, Wiedmer, Tabea, Bergthaler, Andreas, Palmieri, Luigi, Superti-Furga, Giulio
Publicado 2020

The accelerated waning of immunity and reduced effect of booster in patients treated with bDMARD and tsDMARD after SARS-CoV-2 mRNA vaccination

por Tobudic, Selma, Simader, Elisabeth, Deimel, Thomas, Straub, Jennifer, Kartnig, Felix, Heinz, Leonhard X., Mandl, Peter, Haslacher, Helmuth, Perkmann, Thomas, Schneider, Lisa, Nothnagl, Thomas, Radner, Helga, Winkler, Florian, Burgmann, Heinz, Stiasny, Karin, Novacek, Gottfried, Reinisch, Walter, Aletaha, Daniel, Winkler, Stefan, Blüml, Stephan
Publicado 2023

A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs

por Girardi, Enrico, César-Razquin, Adrián, Lindinger, Sabrina, Papakostas, Konstantinos, Konecka, Justyna, Hemmerich, Jennifer, Kickinger, Stefanie, Kartnig, Felix, Gürtl, Bettina, Klavins, Kristaps, Sedlyarov, Vitaly, Ingles-Prieto, Alvaro, Fiume, Giuseppe, Koren, Anna, Lardeau, Charles-Hugues, Kandasamy, Richard Kumaran, Kubicek, Stefan, Ecker, Gerhard F., Superti-Furga, Giulio
Publicado 2020

TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9

por Heinz, Leonhard X., Lee, JangEun, Kapoor, Utkarsh, Kartnig, Felix, Sedlyarov, Vitaly, Papakostas, Konstantinos, César-Razquin, Adrian, Essletzbichler, Patrick, Goldmann, Ulrich, Stefanovic, Adrijana, Bigenzahn, Johannes W., Scorzoni, Stefania, Pizzagalli, Mattia D., Bensimon, Ariel, Müller, André C., King, F. James, Li, Jun, Girardi, Enrico, Mbow, M. Lamine, Whitehurst, Charles E., Rebsamen, Manuele, Superti-Furga, Giulio
Publicado 2020

Heterologous vector versus homologous mRNA COVID-19 booster vaccination in non-seroconverted immunosuppressed patients: a randomized controlled trial

por Mrak, Daniel, Sieghart, Daniela, Simader, Elisabeth, Tobudic, Selma, Radner, Helga, Mandl, Peter, Göschl, Lisa, Koblischke, Maximilian, Hommer, Nikolaus, Wagner, Angelika, Mayer, Margareta, Schubert, Lorenz, Hartl, Lukas, Kozbial, Karin, Hofer, Philipp, Kartnig, Felix, Hummel, Thomas, Kerschbaumer, Andreas, Deimel, Thomas, Puchner, Antonia, Gudipati, Venugopal, Thalhammer, Renate, Munda, Petra, Uyanik-Ünal, Keziban, Zuckermann, Andreas, Novacek, Gottfried, Reiberger, Thomas, Garner-Spitzer, Erika, Reindl-Schwaighofer, Roman, Kain, Renate, Winkler, Stefan, Smolen, Josef S., Stiasny, Karin, Fischer, Gottfried F., Perkmann, Thomas, Haslacher, Helmuth, Zeitlinger, Markus, Wiedermann, Ursula, Aberle, Judith H., Aletaha, Daniel, Heinz, Leonhard X., Bonelli, Michael
Publicado 2022