Aspiration-assisted bioprinting of the osteochondral interface

por Ayan, Bugra, Wu, Yang, Karuppagounder, Vengadeshprabhu, Kamal, Fadia, Ozbolat, Ibrahim T.
Publicado 2020

Early Gβγ-GRK2 Inhibition Ameliorates Osteoarthritis Development by Simultaneous Anti-Inflammatory and Chondroprotective Effects

por Karuppagounder, Vengadeshprabhu, Pinamont, William, Yoshioka, Natalie, Elbarbary, Reyad, Kamal, Fadia
Publicado 2022

Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis

por Neitemeier, S, Dolga, A M, Honrath, B, Karuppagounder, S S, Alim, I, Ratan, R R, Culmsee, C
Publicado 2016

Histone Deacetylase Inhibitors and Mithramycin A Impact a Similar Neuroprotective Pathway at a Crossroad between Cancer and Neurodegeneration

por Sleiman, Sama F., Berlin, Jill, Basso, Manuela, S.Karuppagounder, Saravanan, Rohr, Jürgen, Ratan, Rajiv R.
Publicado 2011

The c-Abl inhibitor, Nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease

por Karuppagounder, Senthilkumar S., Brahmachari, Saurav, Lee, Yunjong, Dawson, Valina L., Dawson, Ted M., Ko, Han Seok
Publicado 2014

A STING agonist preconditions against ischaemic stroke via an adaptive antiviral Type 1 interferon response

por Kundu, Nandini, Kumar, Amit, Corona, Carlo, Chen, Yingxin, Seth, Sonia, Karuppagounder, Saravanan S., Ratan, Rajiv R.
Publicado 2022

c-Abl and Parkinson’s Disease: Mechanisms and Therapeutic Potential

por Brahmachari, Saurav, Karuppagounder, Senthilkumar S., Ge, Preston, Lee, Saebom, Dawson, Valina L., Dawson, Ted M., Ko, Han Seok
Publicado 2017

The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson’s disease

por Aimé, Pascaline, Karuppagounder, Saravanan S., Rao, Apeksha, Chen, Yingxin, Burke, Robert E., Ratan, Rajiv R., Greene, Lloyd A.
Publicado 2020

SARS–CoV-2 Mediated Hyperferritinemia and Cardiac Arrest: Preliminary Insights

por VasanthiDharmalingam, Prakash, Karuppagounder, Vengadeshprabhu, Watanabe, Kenichi, Karmouty‐Quintana, Harry, Palaniyandi, Suresh S., Guha, Ashrith, Thandavarayan, Rajarajan A.
Publicado 2021

Ferroptosis in Neurons and Cancer Cells Is Similar But Differentially Regulated by Histone Deacetylase Inhibitors

por Zille, Marietta, Kumar, Amit, Kundu, Nandini, Bourassa, Megan W., Wong, Victor S. C., Willis, Dianna, Karuppagounder, Saravanan S., Ratan, Rajiv R.
Publicado 2019

Transcript shortening via alternative polyadenylation promotes gene expression during fracture healing

por Khajuria, Deepak Kumar, Nowak, Irena, Leung, Ming, Karuppagounder, Vengadeshprabhu, Imamura, Yuka, Norbury, Christopher C., Kamal, Fadia, Elbarbary, Reyad A.
Publicado 2023

Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice

por Karuppagounder, Vengadeshprabhu, Giridharan, Vijayasree V., Arumugam, Somasundaram, Sreedhar, Remya, Palaniyandi, Suresh S., Krishnamurthy, Prasanna, Quevedo, Joao, Watanabe, Kenichi, Konishi, Tetsuya, Thandavarayan, Rajarajan A.
Publicado 2016

Synthetic mRNAs Drive Highly Efficient iPS Cell Differentiation to Dopaminergic Neurons

por Xue, Yingchao, Zhan, Xiping, Sun, Shisheng, Karuppagounder, Senthilkumar S., Xia, Shuli, Dawson, Valina L., Dawson, Ted M., Laterra, John, Zhang, Jianmin, Ying, Mingyao
Publicado 2018

Curcumin ameliorates streptozotocin-induced liver damage through modulation of endoplasmic reticulum stress-mediated apoptosis in diabetic rats

por Afrin, R., Arumugam, S., Soetikno, V., Thandavarayan, R. A., Pitchaimani, V., Karuppagounder, V., Sreedhar, R., Harima, M., Suzuki, H., Miyashita, S., Nomoto, M., Suzuki, K., Watanabe, K.
Publicado 2015

PARIS induced defects in mitochondrial biogenesis drive dopamine neuron loss under conditions of parkin or PINK1 deficiency

por Pirooznia, Sheila K., Yuan, Changqing, Khan, Mohammed Repon, Karuppagounder, Senthilkumar S., Wang, Luan, Xiong, Yulan, Kang, Sung Ung, Lee, Yunjong, Dawson, Valina L., Dawson, Ted M.
Publicado 2020

Le Carbone prevents liver damage in non-alcoholic steatohepatitis-hepatocellular carcinoma mouse model via AMPKα-SIRT1 signaling pathway activation

por Afrin, Mst. Rejina, Arumugam, Somasundaram, Pitchaimani, Vigneshwaran, Karuppagounder, Vengadeshprabhu, Thandavarayan, Rajarajan Amirthalingam, Harima, Meilei, Hossain, Chowdhury Faiz, Suzuki, Kenji, Sone, Hirohito, Matsubayashi, Yasuhiro, Watanabe, Kenichi
Publicado 2021

Structural changes in the collagen network of joint tissues in late stages of murine OA

por Yoshioka, Natalie K., Young, Gregory M., Khajuria, Deepak Kumar, Karuppagounder, Vengadeshprabhu, Pinamont, William J., Fanburg-Smith, Julie C., Abraham, Thomas, Elbarbary, Reyad A., Kamal, Fadia
Publicado 2022

STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy

por Hinkle, Jared T., Patel, Jaimin, Panicker, Nikhil, Karuppagounder, Senthilkumar S., Biswas, Devanik, Belingon, Bonn, Chen, Rong, Brahmachari, Saurav, Pletnikova, Olga, Troncoso, Juan C., Dawson, Valina L., Dawson, Ted M.
Publicado 2022

Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery

por Wei, George Z., Saraswat Ohri, Sujata, Khattar, Nicolas K., Listerman, Adam W., Doyle, Catherine H., Andres, Kariena R., Karuppagounder, Saravanan S., Ratan, Rajiv R., Whittemore, Scott R., Hetman, Michal
Publicado 2021

Pruni cortex ameliorates skin inflammation possibly through HMGB1-NFκB pathway in house dust mite induced atopic dermatitis NC/Nga transgenic mice

por Watanabe, Kenichi, Karuppagounder, Vengadeshprabhu, Arumugam, Somasundaram, Thandavarayan, Rajarajan A., Pitchaimani, Vigneshwaran, Sreedhar, Remya, Afrin, Rejina, Harima, Meilei, Suzuki, Hiroshi, Suzuki, Kenji, Nakamura, Takashi, Nomoto, Mayumi, Miyashita, Shizuka, Fukumoto, Kyoko, Ueno, Kazuyuki
Publicado 2015