crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus

por Karvelis, Tautvydas, Gasiunas, Giedrius, Miksys, Algirdas, Barrangou, Rodolphe, Horvath, Philippe, Siksnys, Virginijus
Publicado 2013

Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements

por Karvelis, Tautvydas, Gasiunas, Giedrius, Young, Joshua, Bigelyte, Greta, Silanskas, Arunas, Cigan, Mark, Siksnys, Virginijus
Publicado 2015

Oriented Soft DNA Curtains for Single-Molecule Imaging

por Kopu̅stas, Aurimas, Ivanovaitė, Šaru̅nė, Rakickas, Tomas, Pocevičiu̅tė, Ernesta, Paksaitė, Justė, Karvelis, Tautvydas, Zaremba, Mindaugas, Manakova, Elena, Tutkus, Marijonas
Publicado 2021

Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease

por Karvelis, Tautvydas, Druteika, Gytis, Bigelyte, Greta, Budre, Karolina, Zedaveinyte, Rimante, Silanskas, Arunas, Kazlauskas, Darius, Venclovas, Česlovas, Siksnys, Virginijus
Publicado 2021

5′ modifications to CRISPR–Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage

por Mullally, Grace, van Aelst, Kara, Naqvi, Mohsin M, Diffin, Fiona M, Karvelis, Tautvydas, Gasiunas, Giedrius, Siksnys, Virginijus, Szczelkun, Mark D
Publicado 2020

PAM recognition by miniature CRISPR–Cas12f nucleases triggers programmable double-stranded DNA target cleavage

por Karvelis, Tautvydas, Bigelyte, Greta, Young, Joshua K, Hou, Zhenglin, Zedaveinyte, Rimante, Budre, Karolina, Paulraj, Sushmitha, Djukanovic, Vesna, Gasior, Stephen, Silanskas, Arunas, Venclovas, Česlovas, Siksnys, Virginijus
Publicado 2020

Targeted gene editing by transfection of in vitro reconstituted Streptococcus thermophilus Cas9 nuclease complex

por Glemzaite, Monika, Balciunaite, Egle, Karvelis, Tautvydas, Gasiunas, Giedrius, Grusyte, Mantvyda M, Alzbutas, Gediminas, Jurcyte, Aiste, Anderson, Emily M, Maksimova, Elena, Smith, Anja J, Lubys, Arvydas, Zaliauskiene, Lolita, Siksnys, Virginijus
Publicado 2015

Miniature type V-F CRISPR-Cas nucleases enable targeted DNA modification in cells

por Bigelyte, Greta, Young, Joshua K., Karvelis, Tautvydas, Budre, Karolina, Zedaveinyte, Rimante, Djukanovic, Vesna, Van Ginkel, Elizabeth, Paulraj, Sushmitha, Gasior, Stephen, Jones, Spencer, Feigenbutz, Lanie, Clair, Grace St., Barone, Pierluigi, Bohn, Jennifer, Acharya, Ananta, Zastrow-Hayes, Gina, Henkel-Heinecke, Selgar, Silanskas, Arunas, Seidel, Ralf, Siksnys, Virginijus
Publicado 2021

A catalogue of biochemically diverse CRISPR-Cas9 orthologs

por Gasiunas, Giedrius, Young, Joshua K., Karvelis, Tautvydas, Kazlauskas, Darius, Urbaitis, Tomas, Jasnauskaite, Monika, Grusyte, Mantvyda M., Paulraj, Sushmitha, Wang, Po-Hao, Hou, Zhenglin, Dooley, Shane K., Cigan, Mark, Alarcon, Clara, Chilcoat, N. Doane, Bigelyte, Greta, Curcuru, Jennifer L., Mabuchi, Megumu, Sun, Zhiyi, Fuchs, Ryan T., Schildkraut, Ezra, Weigele, Peter R., Jack, William E., Robb, G. Brett, Venclovas, Česlovas, Siksnys, Virginijus
Publicado 2020