Molecular Mechanisms Associated with ROR1-Mediated Drug Resistance: Crosstalk with Hippo-YAP/TAZ and BMI-1 Pathways

por Karvonen, Hanna, Barker, Harlan, Kaleva, Laura, Niininen, Wilhelmiina, Ungureanu, Daniela
Publicado 2019

Evaluating Targeted Therapies in Ovarian Cancer Metabolism: Novel Role for PCSK9 and Second Generation mTOR Inhibitors

por Jacome Sanz, Dafne, Raivola, Juuli, Karvonen, Hanna, Arjama, Mariliina, Barker, Harlan, Murumägi, Astrid, Ungureanu, Daniela
Publicado 2021

New insights into the molecular mechanisms of ROR1, ROR2, and PTK7 signaling from the proteomics and pharmacological modulation of ROR1 interactome

por Raivola, Juuli, Dini, Alice, Salokas, Kari, Karvonen, Hanna, Niininen, Wilhelmiina, Piki, Emilia, Varjosalo, Markku, Ungureanu, Daniela
Publicado 2022

Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness

por Karvonen, Hanna, Arjama, Mariliina, Kaleva, Laura, Niininen, Wilhelmiina, Barker, Harlan, Koivisto-Korander, Riitta, Tapper, Johanna, Pakarinen, Päivi, Lassus, Heini, Loukovaara, Mikko, Bützow, Ralf, Kallioniemi, Olli, Murumägi, Astrid, Ungureanu, Daniela
Publicado 2020

Multiomics characterization implicates PTK7 in ovarian cancer EMT and cell plasticity and offers strategies for therapeutic intervention

por Raivola, Juuli, Dini, Alice, Karvonen, Hanna, Piki, Emilia, Salokas, Kari, Niininen, Wilhelmiina, Kaleva, Laura, Zhang, Kaiyang, Arjama, Mariliina, Gudoityte, Greta, Seashore-Ludlow, Brinton, Varjosalo, Markku, Kallioniemi, Olli, Hautaniemi, Sampsa, Murumägi, Astrid, Ungureanu, Daniela
Publicado 2022