A novel DNA damage-induced alternative splicing pathway that regulates p53 and cellular senescence markers

por Chen, Jing, Kastan, Michael B.
Publicado 2017

DNA-Damage-Induced Alternative Splicing of p53

por Chen, Jing, Zhang, Dadong, Qin, Xiaodi, Owzar, Kouros, McCann, Jennifer J., Kastan, Michael B.
Publicado 2021

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

por Bekker-Jensen, Simon, Lukas, Claudia, Kitagawa, Risa, Melander, Fredrik, Kastan, Michael B., Bartek, Jiri, Lukas, Jiri
Publicado 2006

The Telomeric Protein TRF2 Binds the ATM Kinase and Can Inhibit the ATM-Dependent DNA Damage Response

por Karlseder, Jan, Hoke, Kristina, Mirzoeva, Olga K, Bakkenist, Christopher, Kastan, Michael B, Petrini, John H. J, de Lange, Titia
Publicado 2004

The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair

por Henriksson, Sofia, Rassoolzadeh, Hanif, Hedström, Elisabeth, Coucoravas, Christos, Julner, Alexander, Goldstein, Michael, Imreh, Gabriela, Zhivotovsky, Boris, Kastan, Michael B., Helleday, Thomas, Farnebo, Marianne
Publicado 2014

Self-inflicted DNA double-strand breaks sustain tumorigenicity and stemness of cancer cells

por Liu, Xinjian, Li, Fang, Huang, Qian, Zhang, Zhengxiang, Zhou, Ling, Deng, Yu, Zhou, Min, Fleenor, Donald E, Wang, He, Kastan, Michael B, Li, Chuan-Yuan
Publicado 2017

Impaired endoplasmic reticulum-mitochondrial signaling in ataxia-telangiectasia

por Yeo, Abrey J., Chong, Kok L., Gatei, Magtouf, Zou, Dongxiu, Stewart, Romal, Withey, Sarah, Wolvetang, Ernst, Parton, Robert G., Brown, Adam D., Kastan, Michael B., Coman, David, Lavin, Martin F.
Publicado 2020

ATM Functions at the Peroxisome to Induce Pexophagy in Response to ROS

por Zhang, Jiangwei, Tripathi, Durga Nand, Jing, Ji, Alexander, Angela, Kim, Jinhee, Powell, Reid T., Dere, Ruhee, Tait-Mulder, Jacqueline, Lee, Ji-Hoon, Paull, Tanya T., Pandita, Raj K., Charaka, Vijaya K., Pandita, Tej K., Kastan, Michael B., Walker, Cheryl Lyn
Publicado 2015

Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness

por McGill, Janet B., Johnson, Mariko, Hurst, Stacy, Cade, William T., Yarasheski, Kevin E., Ostlund, Richard E., Schechtman, Kenneth B., Razani, Babak, Kastan, Michael B., McClain, Donald A., de las Fuentes, Lisa, Davila-Roman, Victor G., Ory, Daniel S., Wickline, Samuel A., Semenkovich, Clay F.
Publicado 2019

A TSC signaling node at the peroxisome regulates mTORC1 and autophagy in response to ROS

por Zhang, Jiangwei, Kim, Jinhee, Alexander, Angela, Cai, Shengli, Tripathi, Durga Nand, Dere, Ruhee, Tee, Andrew R., Tait-Mulder, Jacqueline, Di Nardo, Alessia, Han, Juliette M., Kwiatkowski, Erica, Dunlop, Elaine A., Dodd, Kayleigh M., Folkerth, Rebecca D., Faust, Phyllis L., Kastan, Michael B., Sahin, Mustafa, Walker, Cheryl Lyn
Publicado 2013