Inclisiran for the treatment of hypercholesterolaemia: implications and unanswered questions from the ORION trials

por Cupido, Arjen J, Kastelein, John J P
Publicado 2020

Cholesteryl ester transfer protein inhibitors: from high-density lipoprotein cholesterol to low-density lipoprotein cholesterol lowering agents?

por Nurmohamed, Nick S, Ditmarsch, Marc, Kastelein, John J P
Publicado 2021

The effect of CETP inhibitors on new-onset diabetes: a systematic review and meta-analysis

por Dangas, Katerina, Navar, Ann-Marie, Kastelein, John J P
Publicado 2022

Lipid Measures and Cardiovascular Disease Prediction

por van Wijk, Diederik F., Stroes, Erik S. G., Kastelein, John J. P.
Publicado 2009

CETP and SGLT2 inhibitor combination therapy improves glycemic control

por Khomtchouk, Bohdan B., Sun, Patrick, Ditmarsch, Marc, Kastelein, John J.P., Davidson, Michael H.
Publicado 2023

Changes in Mipomersen Dosing Regimen Provide Similar Exposure With Improved Tolerability in Randomized Placebo‐Controlled Study of Healthy Volunteers

por Flaim, JoAnn D., Grundy, John S., Baker, Brenda F., McGowan, Mary P., Kastelein, John J. P.
Publicado 2014

Comparison of low-density lipoprotein cholesterol equations in patients with dyslipidaemia receiving cholesterol ester transfer protein inhibition

por Martin, Seth S, Ditmarsch, Marc, Simmons, Mark, Alp, Nicholas, Turner, Traci, Davidson, Michael H, Kastelein, John J P
Publicado 2022

Effects of Supra-Physiological Levothyroxine Dosages on Liver Parameters, Lipids and Lipoproteins in Healthy Volunteers: A Randomized Controlled Crossover Study

por Sjouke, Barbara, Elbers, Laura P. B., van Zaane, Bregje, Kastelein, John J. P., Hovingh, G. Kees, Gerdes, Victor E. A.
Publicado 2017

Quality Assessment of the Genetic Test for Familial Hypercholesterolemia in The Netherlands

por Kindt, Iris, Huijgen, Roeland, Boekel, Marieke, van der Gaag, Kristiaan J., Defesche, Joep C., Kastelein, John J. P., de Knijff, Peter
Publicado 2013

Efficacy and Safety of Alirocumab in Patients with Heterozygous Familial Hypercholesterolemia not Adequately Controlled with Current Lipid-Lowering Therapy: Design and Rationale of...

por Kastelein, John J. P., Robinson, Jennifer G., Farnier, Michel, Krempf, Michel, Langslet, Gisle, Lorenzato, Christelle, Gipe, Daniel A., Baccara-Dinet, Marie T.
Publicado 2014

Safety and efficacy of LY3015014, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9): a randomized, placebo-controlled Phase 2 study

por Kastelein, John J.P., Nissen, Steven E., Rader, Daniel J., Hovingh, G. Kees, Wang, Ming-Dauh, Shen, Tong, Krueger, Kathryn A.
Publicado 2016

Cholesteryl Ester Transfer Protein Inhibition Reduces Major Adverse Cardiovascular Events by Lowering Apolipoprotein B Levels

por Nelson, Adam J., Sniderman, Allan D., Ditmarsch, Marc, Dicklin, Mary R., Nicholls, Stephen J., Davidson, Michael H., Kastelein, John J. P.
Publicado 2022

Two Years after Molecular Diagnosis of Familial Hypercholesterolemia: Majority on Cholesterol-Lowering Treatment but a Minority Reaches Treatment Goal

por Huijgen, Roeland, Kindt, Iris, Verhoeven, Sjoerd B. J., Sijbrands, Eric J. G., Vissers, Maud N., Kastelein, John J. P., Hutten, Barbara A.
Publicado 2010

Effect of alirocumab dose increase on LDL lowering and lipid goal attainment in patients with dyslipidemia

por Kastelein, John J.P., Kereiakes, Dean J., Cannon, Christopher P., Bays, Harold E., Minini, Pascal, Lee, L. Veronica, Maroni, Jaman, Farnier, Michel
Publicado 2017

Carriers of Loss-of-Function Mutations in ABCA1 Display Pancreatic β-Cell Dysfunction

por Vergeer, Menno, Brunham, Liam R., Koetsveld, Joris, Kruit, Janine K., Verchere, C. Bruce, Kastelein, John J.P., Hayden, Michael R., Stroes, Erik S.G.
Publicado 2010

Efficacy and Safety of Pitavastatin in Children and Adolescents with Familial Hypercholesterolemia in Japan and Europe

por Harada-Shiba, Mariko, Kastelein, John J.P., Hovingh, G. Kees, Ray, Kausik K., Ohtake, Akira, Arisaka, Osamu, Ohta, Takao, Okada, Tomoo, Suganami, Hideki, Wiegman, Albert
Publicado 2018

Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia

por Vissers, Maud N., Trip, Mieke D., Pritchard, P. Haydn, Tam, Patrick, Lukic, Tatjana, de Sain-van der Velden, Monique G., de Barse, Martina, Kastelein, John J. P.
Publicado 2008

Long-Term Statin Treatment in Children with Familial Hypercholesterolemia: More Insight into Tolerability and Adherence

por Braamskamp, Marjet J. A. M., Kusters, D. Meeike, Avis, Hans J., Smets, Ellen M. A., Wijburg, Frits A., Kastelein, John J. P., Wiegman, Albert, Hutten, Barbara A.
Publicado 2015

A systematic review and meta-analysis of the effect of statins on plasma asymmetric dimethylarginine concentrations

por Serban, Corina, Sahebkar, Amirhossein, Ursoniu, Sorin, Mikhailidis, Dimitri P., Rizzo, Manfredi, Lip, Gregory Y.H., Kees Hovingh, G., Kastelein, John J.P., Kalinowski, Leszek, Rysz, Jacek, Banach, Maciej
Publicado 2015

Both Paraoxonase-1 Genotype and Activity Do Not Predict the Risk of Future Coronary Artery Disease; the EPIC-Norfolk Prospective Population Study

por Birjmohun, Rakesh S., Vergeer, Menno, Stroes, Erik S. G., Sandhu, Manjinder S., Ricketts, Sally L., Tanck, Michael W., Wareham, Nicholas J., Jukema, J. Wouter, Kastelein, John J. P., Khaw, Kay-Tee, Boekholdt, S. Matthijs
Publicado 2009