Cracking the code of cellular protein–protein interactions: Alphafold and whole‐cell crosslinking to the rescue

por Träger, Toni, Kastritis, Panagiotis L
Publicado 2023

Enzymatic complexes across scales

por Kastritis, Panagiotis L., Gavin, Anne-Claude
Publicado 2018

Unstructured regions of large enzymatic complexes control the availability of metabolites with signaling functions

por Skalidis, Ioannis, Tüting, Christian, Kastritis, Panagiotis L.
Publicado 2020

IRAA: A statistical tool for investigating a protein–protein interaction interface from multiple structures

por Belapure, Jaydeep, Sorokina, Marija, Kastritis, Panagiotis L.
Publicado 2023

On the binding affinity of macromolecular interactions: daring to ask why proteins interact

por Kastritis, Panagiotis L., Bonvin, Alexandre M. J. J.
Publicado 2013

Detecting Protein Communities in Native Cell Extracts by Machine Learning: A Structural Biologist’s Perspective

por Kyrilis, Fotis L., Belapure, Jaydeep, Kastritis, Panagiotis L.
Publicado 2021

Cryo-EM of a heterogeneous biochemical fraction elucidates multiple protein complexes from a multicellular thermophilic eukaryote

por Semchonok, Dmitry A., Kyrilis, Fotis L., Hamdi, Farzad, Kastritis, Panagiotis L.
Publicado 2023

Structural analysis of 70S ribosomes by cross-linking/mass spectrometry reveals conformational plasticity

por Tüting, Christian, Iacobucci, Claudio, Ihling, Christian H., Kastritis, Panagiotis L., Sinz, Andrea
Publicado 2020

The structural principles underlying molybdenum insertase complex assembly

por Hassan, Ahmed H., Ihling, Christian, Iacobucci, Claudio, Kastritis, Panagiotis L., Sinz, Andrea, Kruse, Tobias
Publicado 2023

HADDOCK(2P2I): A Biophysical Model for Predicting the Binding Affinity of Protein–Protein Interaction Inhibitors

por Kastritis, Panagiotis L., Rodrigues, João P. G. L. M., Bonvin, Alexandre M. J. J.
Publicado 2014

Building Macromolecular Assemblies by Information-driven Docking: INTRODUCING THE HADDOCK MULTIBODY DOCKING SERVER

por Karaca, Ezgi, Melquiond, Adrien S. J., de Vries, Sjoerd J., Kastritis, Panagiotis L., Bonvin, Alexandre M. J. J.
Publicado 2010

Subnanometre-resolution structure of the doublet microtubule reveals new classes of microtubule-associated proteins

por Ichikawa, Muneyoshi, Liu, Dinan, Kastritis, Panagiotis L., Basu, Kaustuv, Hsu, Tzu Chin, Yang, Shunkai, Bui, Khanh Huy
Publicado 2017

Cryo-EM snapshots of a native lysate provide structural insights into a metabolon-embedded transacetylase reaction

por Tüting, Christian, Kyrilis, Fotis L., Müller, Johannes, Sorokina, Marija, Skalidis, Ioannis, Hamdi, Farzad, Sadian, Yashar, Kastritis, Panagiotis L.
Publicado 2021

dMM-PBSA: A New HADDOCK Scoring Function for Protein-Peptide Docking

por Spiliotopoulos, Dimitrios, Kastritis, Panagiotis L., Melquiond, Adrien S. J., Bonvin, Alexandre M. J. J., Musco, Giovanna, Rocchia, Walter, Spitaleri, Andrea
Publicado 2016

An Electrostatically-steered Conformational Selection Mechanism Promotes SARS-CoV-2 Spike Protein Variation

por Sorokina, Marija, Belapure, Jaydeep, Tüting, Christian, Paschke, Reinhard, Papasotiriou, Ioannis, Rodrigues, João P.G.L.M., Kastritis, Panagiotis L.
Publicado 2022

Structural assessment of the full-length wild-type tumor suppressor protein p53 by mass spectrometry-guided computational modeling

por Di Ianni, Alessio, Tüting, Christian, Kipping, Marc, Ihling, Christian H., Köppen, Janett, Iacobucci, Claudio, Arlt, Christian, Kastritis, Panagiotis L., Sinz, Andrea
Publicado 2023

Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design

por Sorokina, Marija, M. C. Teixeira, João, Barrera-Vilarmau, Susana, Paschke, Reinhard, Papasotiriou, Ioannis, Rodrigues, João P. G. L. M., Kastritis, Panagiotis L.
Publicado 2020

Insights on cross-species transmission of SARS-CoV-2 from structural modeling

por Rodrigues, João P. G. L. M., Barrera-Vilarmau, Susana, M. C. Teixeira, João, Sorokina, Marija, Seckel, Elizabeth, Kastritis, Panagiotis L., Levitt, Michael
Publicado 2020

Cryo-EM structure of the SEA complex

por Tafur, Lucas, Hinterndorfer, Kerstin, Gabus, Caroline, Lamanna, Chiara, Bergmann, Ariane, Sadian, Yashar, Hamdi, Farzad, Kyrilis, Fotis L., Kastritis, Panagiotis L., Loewith, Robbie
Publicado 2022

Solubilization, purification, and characterization of the hexameric form of phosphatidylserine synthase from Candida albicans

por Zhou, Yue, Syed, Jawhar H., Semchonok, Dmitry A., Wright, Edward, Kyrilis, Fotis L., Hamdi, Farzad, Kastritis, Panagiotis L., Bruce, Barry D., Reynolds, Todd B.
Publicado 2023