Big Lessons from Tiny Flies: Drosophila melanogaster as a Model to Explore Dysfunction of Dopaminergic and Serotonergic Neurotransmitter Systems

por Kasture, Ameya Sanjay, Hummel, Thomas, Sucic, Sonja, Freissmuth, Michael
Publicado 2018

Molecular and Clinical Repercussions of GABA Transporter 1 Variants Gone Amiss: Links to Epilepsy and Developmental Spectrum Disorders

por Fischer, Florian P., Kasture, Ameya S., Hummel, Thomas, Sucic, Sonja
Publicado 2022

A behavioral task with more opportunities for memory acquisition promotes the survival of new neurons in the adult dentate gyrus

por Aasebø, Ida E. J., Kasture, Ameya Sanjay, Passeggeri, Marzia, Tashiro, Ayumu
Publicado 2018

When transporters fail to be transported: how to rescue folding-deficient SLC6 transporters

por Sucic, Sonja, Kasture, Ameya, Mazhar Asjad, H. M., Kern, Carina, El-Kasaby, Ali, Freissmuth, Michael
Publicado 2016

Pharmacochaperoning in a Drosophila model system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism

por Asjad, H. M. Mazhar, Kasture, Ameya, El-Kasaby, Ali, Sackel, Michael, Hummel, Thomas, Freissmuth, Michael, Sucic, Sonja
Publicado 2017

Drosophila melanogaster as a model for unraveling unique molecular features of epilepsy elicited by human GABA transporter 1 variants

por Kasture, Ameya S., Fischer, Florian P., Kunert, Lisa, Burger, Melanie L., Burgstaller, Alexander C., El-Kasaby, Ali, Hummel, Thomas, Sucic, Sonja
Publicado 2023

Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones

por Kasture, Ameya, El-Kasaby, Ali, Szöllősi, Daniel, Asjad, H. M. Mazhar, Grimm, Alexandra, Stockner, Thomas, Hummel, Thomas, Freissmuth, Michael, Sucic, Sonja
Publicado 2016

Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates

por Bhat, Shreyas, Hasenhuetl, Peter S., Kasture, Ameya, El-Kasaby, Ali, Baumann, Michael H., Blough, Bruce E., Sucic, Sonja, Sandtner, Walter, Freissmuth, Michael
Publicado 2017

Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans

por Pretsch, Dagmar, Rollinger, Judith Maria, Schmid, Axel, Genov, Miroslav, Wöhrer, Teresa, Krenn, Liselotte, Moloney, Mark, Kasture, Ameya, Hummel, Thomas, Pretsch, Alexander
Publicado 2020

A mechanism of uncompetitive inhibition of the serotonin transporter

por Bhat, Shreyas, El-Kasaby, Ali, Kasture, Ameya, Boytsov, Danila, Reichelt, Julian B, Hummel, Thomas, Sucic, Sonja, Pifl, Christian, Freissmuth, Michael, Sandtner, Walter
Publicado 2023

Standardized phytotherapic extracts rescue anomalous locomotion and electrophysiological responses of TDP-43 Drosophila melanogaster model of ALS

por Maccioni, Riccardo, Setzu, Maria Dolores, Talani, Giuseppe, Solari, Paolo, Kasture, Ameya, Sucic, Sonja, Porru, Simona, Muroni, Patrizia, Sanna, Enrico, Kasture, Sanjay, Acquas, Elio, Liscia, Anna
Publicado 2018

Tropane-Based Ibogaine Analog Rescues Folding-Deficient Serotonin and Dopamine Transporters

por Bhat, Shreyas, Guthrie, Daryl A., Kasture, Ameya, El-Kasaby, Ali, Cao, Jianjing, Bonifazi, Alessandro, Ku, Therese, Giancola, JoLynn B., Hummel, Thomas, Freissmuth, Michael, Newman, Amy Hauck
Publicado 2020