Kinetic analysis of the role of the tyrosine 13, phenylalanine 56 and glutamine 54 network in the U1A/U1 hairpin II interaction

por Law, Michael J., Chambers, Eric J., Katsamba, Phinikoula S., Haworth, Ian S., Laird-Offringa, Ite A.
Publicado 2005

DIP/Dpr interactions and the evolutionary design of specificity in protein families

por Sergeeva, Alina P., Katsamba, Phinikoula S., Cosmanescu, Filip, Brewer, Joshua J., Ahlsen, Goran, Mannepalli, Seetha, Shapiro, Lawrence, Honig, Barry
Publicado 2020

Structural Basis of Antibody Conformation and Stability Modulation by Framework Somatic Hypermutation

por Sheng, Zizhang, Bimela, Jude S., Katsamba, Phinikoula S., Patel, Saurabh D., Guo, Yicheng, Zhao, Haiqing, Guo, Youzhong, Kwong, Peter D., Shapiro, Lawrence
Publicado 2022

Functional properties of the spike glycoprotein of the emerging SARS-CoV-2 variant B.1.1.529

por Wang, Qian, Anang, Saumya, Iketani, Sho, Guo, Yicheng, Liu, Lihong, Katsamba, Phinikoula S., Shapiro, Lawrence, Ho, David D., Sodroski, Joseph G.
Publicado 2022

The role of positively charged amino acids and electrostatic interactions in the complex of U1A protein and U1 hairpin II RNA

por Law, Michael J., Linde, Michael E., Chambers, Eric J., Oubridge, Chris, Katsamba, Phinikoula S., Nilsson, Lennart, Haworth, Ian S., Laird-Offringa, Ite A.
Publicado 2006

Affinity requirements for control of synaptic targeting and neuronal cell survival by heterophilic IgSF cell adhesion molecules

por Xu, Shuwa, Sergeeva, Alina P., Katsamba, Phinikoula S., Mannepalli, Seetha, Bahna, Fabiana, Bimela, Jude, Zipursky, S. Lawrence, Shapiro, Lawrence, Honig, Barry, Zinn, Kai
Publicado 2022

How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition

por Goodman, Kerry Marie, Katsamba, Phinikoula S, Rubinstein, Rotem, Ahlsén, Göran, Bahna, Fabiana, Mannepalli, Seetha, Dan, Hanbin, Sampogna, Rosemary V, Shapiro, Lawrence, Honig, Barry
Publicado 2022

Molecular basis of sidekick-mediated cell-cell adhesion and specificity

por Goodman, Kerry M, Yamagata, Masahito, Jin, Xiangshu, Mannepalli, Seetha, Katsamba, Phinikoula S, Ahlsén, Göran, Sergeeva, Alina P, Honig, Barry, Sanes, Joshua R, Shapiro, Lawrence
Publicado 2016

Ubiquitin-dependent regulation of a conserved DMRT protein controls sexually dimorphic synaptic connectivity and behavior

por Bayer, Emily A, Stecky, Rebecca C, Neal, Lauren, Katsamba, Phinikoula S, Ahlsen, Goran, Balaji, Vishnu, Hoppe, Thorsten, Shapiro, Lawrence, Oren-Suissa, Meital, Hobert, Oliver
Publicado 2020

Free Energy Perturbation Calculations of Mutation Effects on SARS-CoV-2 RBD::ACE2 Binding Affinity

por Sergeeva, Alina P., Katsamba, Phinikoula S., Liao, Junzhuo, Sampson, Jared M., Bahna, Fabiana, Mannepalli, Seetha, Morano, Nicholas C., Shapiro, Lawrence, Friesner, Richard A., Honig, Barry
Publicado 2023

Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior

por Brasch, Julia, Katsamba, Phinikoula S., Harrison, Oliver J., Ahlsén, Göran, Troyanovsky, Regina B., Indra, Indrajyoti, Kaczynska, Anna, Kaeser, Benjamin, Troyanovsky, Sergey, Honig, Barry, Shapiro, Lawrence
Publicado 2018

Nectin ectodomain structures reveal a canonical adhesive interface

por Harrison, Oliver J., Vendome, Jeremie, Brasch, Julia, Jin, Xiangshu, Hong, Soonjin, Katsamba, Phinikoula S., Ahlsen, Goran, Troyanovsky, Regina B., Troyanovsky, Sergey M., Honig, Barry, Shapiro, Lawrence
Publicado 2012

Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered δ-Protocadherins

por Harrison, Oliver J., Brasch, Julia, Katsamba, Phinikoula S., Ahlsen, Goran, Noble, Alex J., Dan, Hanbin, Sampogna, Rosemary V., Potter, Clinton S., Carragher, Bridget, Honig, Barry, Shapiro, Lawrence
Publicado 2020

Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain

por Cerutti, Gabriele, Guo, Yicheng, Wang, Pengfei, Nair, Manoj S., Wang, Maple, Huang, Yaoxing, Yu, Jian, Liu, Lihong, Katsamba, Phinikoula S., Bahna, Fabiana, Reddem, Eswar R., Kwong, Peter D., Ho, David D., Sheng, Zizhang, Shapiro, Lawrence
Publicado 2021

Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function

por Blockus, Heike, Rolotti, Sebi V., Szoboszlay, Miklos, Peze-Heidsieck, Eugénie, Ming, Tiffany, Schroeder, Anna, Apostolo, Nuno, Vennekens, Kristel M., Katsamba, Phinikoula S., Bahna, Fabiana, Mannepalli, Seetha, Ahlsen, Goran, Honig, Barry, Shapiro, Lawrence, de Wit, Joris, Losonczy, Attila, Polleux, Franck
Publicado 2021

Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class

por Rapp, Micah, Guo, Yicheng, Reddem, Eswar R., Yu, Jian, Liu, Lihong, Wang, Pengfei, Cerutti, Gabriele, Katsamba, Phinikoula, Bimela, Jude S., Bahna, Fabiana A., Mannepalli, Seetha M., Zhang, Baoshan, Kwong, Peter D., Huang, Yaoxing, Ho, David D., Shapiro, Lawrence, Sheng, Zizhang
Publicado 2021

Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2

por Luo, Mengxiao, Zhou, Biao, Reddem, Eswar R., Tang, Bingjie, Chen, Bohao, Zhou, Runhong, Liu, Hang, Liu, Lihong, Katsamba, Phinikoula S., Au, Ka-Kit, Man, Hiu-On, To, Kelvin Kai-Wang, Yuen, Kwok-Yung, Shapiro, Lawrence, Dang, Shangyu, Ho, David D., Chen, Zhiwei
Publicado 2023

Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite

por Cerutti, Gabriele, Guo, Yicheng, Zhou, Tongqing, Gorman, Jason, Lee, Myungjin, Rapp, Micah, Reddem, Eswar R., Yu, Jian, Bahna, Fabiana, Bimela, Jude, Huang, Yaoxing, Katsamba, Phinikoula S., Liu, Lihong, Nair, Manoj S., Rawi, Reda, Olia, Adam S., Wang, Pengfei, Zhang, Baoshan, Chuang, Gwo-Yu, Ho, David D., Sheng, Zizhang, Kwong, Peter D., Shapiro, Lawrence
Publicado 2021

Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains

por Zhou, Tongqing, Tsybovsky, Yaroslav, Gorman, Jason, Rapp, Micah, Cerutti, Gabriele, Chuang, Gwo-Yu, Katsamba, Phinikoula S., Sampson, Jared M., Schön, Arne, Bimela, Jude, Boyington, Jeffrey C., Nazzari, Alexandra, Olia, Adam S., Shi, Wei, Sastry, Mallika, Stephens, Tyler, Stuckey, Jonathan, Teng, I-Ting, Wang, Pengfei, Wang, Shuishu, Zhang, Baoshan, Friesner, Richard A., Ho, David D., Mascola, John R., Shapiro, Lawrence, Kwong, Peter D.
Publicado 2020

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

por Zhou, Tongqing, Teng, I-Ting, Olia, Adam S., Cerutti, Gabriele, Gorman, Jason, Nazzari, Alexandra, Shi, Wei, Tsybovsky, Yaroslav, Wang, Lingshu, Wang, Shuishu, Zhang, Baoshan, Zhang, Yi, Katsamba, Phinikoula S., Petrova, Yuliya, Banach, Bailey B., Fahad, Ahmed S., Liu, Lihong, Lopez Acevedo, Sheila N., Madan, Bharat, de Souza, Matheus Oliveira, Pan, Xiaoli, Wang, Pengfei, Wolfe, Jacy R., Yin, Michael, Ho, David D., Phung, Emily, DiPiazza, Anthony, Chang, Lauren, Abiona, Olubukula, Corbett, Kizzmekia S., DeKosky, Brandon J., Graham, Barney S., Mascola, John R., Misasi, John, Ruckwardt, Tracy, Sullivan, Nancy J., Shapiro, Lawrence, Kwong, Peter D.
Publicado 2020