Inositol-requiring 1/X-box-binding protein 1 is a regulatory hub that links endoplasmic reticulum homeostasis with innate immunity and metabolism

por Kaufman, Randal J, Cao, Siyan
Publicado 2010

The impact of the unfolded protein response on human disease

por Wang, Shiyu, Kaufman, Randal J.
Publicado 2012

Interaction between quality control systems for ER protein folding and RNA biogenesis

por Sakaki, Kenjiro, Kaufman, Randal J.
Publicado 2013

Physiological/pathological ramifications of transcription factors in the unfolded protein response

por Han, Jaeseok, Kaufman, Randal J.
Publicado 2017

Functional analysis of the mammalian RNA ligase for IRE1 in the unfolded protein response

por Poothong, Juthakorn, Tirasophon, Witoon, Kaufman, Randal J.
Publicado 2017

Glycoprotein folding and quality-control mechanisms in protein-folding diseases

por Ferris, Sean P., Kodali, Vamsi K., Kaufman, Randal J.
Publicado 2014

Genetic Interactions Due to Constitutive and Inducible Gene Regulation Mediated by the Unfolded Protein Response in C. elegans

por Shen, Xiaohua, Ellis, Ronald E, Sakaki, Kenjiro, Kaufman, Randal J
Publicado 2005

UDP-glucose:glycoprotein glucosyltransferase (UGGT1) promotes substrate solubility in the endoplasmic reticulum

por Ferris, Sean P., Jaber, Nikita S., Molinari, Maurizio, Arvan, Peter, Kaufman, Randal J.
Publicado 2013

Development of a Reporter System Monitoring Regulated Intramembrane Proteolysis of the Transmembrane bZIP Transcription Factor ATF6α

por Kim, Jin-Ik, Kaufman, Randal J., Back, Sung Hoon, Moon, Ja-Young
Publicado 2019

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

por Oda, Yukako, Okada, Tetsuya, Yoshida, Hiderou, Kaufman, Randal J., Nagata, Kazuhiro, Mori, Kazutoshi
Publicado 2006

Genetic Inhibition of Phosphorylation of the Translation Initiation Factor eIF2α Does Not Block Aβ-Dependent Elevation of BACE1 and APP Levels or Reduce Amyloid Pathology in a Mous...

por Sadleir, Katherine R., Eimer, William A., Kaufman, Randal J., Osten, Pavel, Vassar, Robert
Publicado 2014

The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts

por Stauffer, Winston T., Blackwood, Erik A., Azizi, Khalid, Kaufman, Randal J., Glembotski, Christopher C.
Publicado 2020

Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network

por Arensdorf, Angela M., DeZwaan McCabe, Diane, Kaufman, Randal J., Rutkowski, D. Thomas
Publicado 2013

Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux

por Shang, Jie, Gao, Ningguo, Kaufman, Randal J., Ron, David, Harding, Heather P., Lehrman, Mark A.
Publicado 2007

Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca(2+)

por Yong, Jing, Bischof, Helmut, Burgstaller, Sandra, Siirin, Marina, Murphy, Anne, Malli, Roland, Kaufman, Randal J
Publicado 2019

ATF6 is required for efficient rhodopsin clearance and retinal homeostasis in the P23H rho retinitis pigmentosa mouse model

por Lee, Eun-Jin, Chan, Priscilla, Chea, Leon, Kim, Kyle, Kaufman, Randal J., Lin, Jonathan H.
Publicado 2021

Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress–induced cell death during the unfolded protein response

por Hiramatsu, Nobuhiko, Messah, Carissa, Han, Jaeseok, LaVail, Matthew M., Kaufman, Randal J., Lin, Jonathan H.
Publicado 2014

Read-Split-Run: an improved bioinformatics pipeline for identification of genome-wide non-canonical spliced regions using RNA-Seq data

por Bai, Yongsheng, Kinne, Jeff, Donham, Brandon, Jiang, Feng, Ding, Lizhong, Hassler, Justin R., Kaufman, Randal J.
Publicado 2016

RGC-specific ATF4 and/or CHOP deletion rescues glaucomatous neurodegeneration and visual function

por Fang, Fang, Liu, Pingting, Huang, Haoliang, Feng, Xue, Li, Liang, Sun, Yang, Kaufman, Randal J., Hu, Yang
Publicado 2023

The role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin

por Pearse, Bradley R., Tamura, Taku, Sunryd, Johan C., Grabowski, Gregory A., Kaufman, Randal J., Hebert, Daniel N.
Publicado 2010