ReCo: automated NGS read-counting of single and combinatorial CRISPR gRNAs

por Wegner, Martin, Kaulich, Manuel
Publicado 2023

Functional Genomics Approaches to Elucidate Vulnerabilities of Intrinsic and Acquired Chemotherapy Resistance

por Cetin, Ronay, Quandt, Eva, Kaulich, Manuel
Publicado 2021

On the regulation, function, and localization of the DNA-dependent ATPase PICH

por Kaulich, Manuel, Cubizolles, Fabien, Nigg, Erich A.
Publicado 2012

Delayed Mesoderm and Erythroid Differentiation of Murine Embryonic Stem Cells in the Absence of the Transcriptional Regulator FUBP1

por Wesely, Josephine, Steiner, Marlene, Schnütgen, Frank, Kaulich, Manuel, Rieger, Michael A., Zörnig, Martin
Publicado 2017

Cyclin D activates the Rb tumor suppressor by mono-phosphorylation

por Narasimha, Anil M, Kaulich, Manuel, Shapiro, Gary S, Choi, Yoon J, Sicinski, Piotr, Dowdy, Steven F
Publicado 2014

Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs

por Hübner, Nadja C., Wang, Lily Hui-Ching, Kaulich, Manuel, Descombes, Patrick, Poser, Ina, Nigg, Erich A.
Publicado 2009

Efficient CRISPR-rAAV engineering of endogenous genes to study protein function by allele-specific RNAi

por Kaulich, Manuel, Lee, Yeon J., Lönn, Peter, Springer, Aaron D., Meade, Bryan R., Dowdy, Steven F.
Publicado 2015

Enhancing Endosomal Escape for Intracellular Delivery of Macromolecular Biologic Therapeutics

por Lönn, Peter, Kacsinta, Apollo D., Cui, Xian-Shu, Hamil, Alexander S., Kaulich, Manuel, Gogoi, Khirud, Dowdy, Steven F.
Publicado 2016

Protein import motor complex reacts to mitochondrial misfolding by reducing protein import and activating mitophagy

por Michaelis, Jonas Benjamin, Brunstein, Melinda Elaine, Bozkurt, Süleyman, Alves, Ludovico, Wegner, Martin, Kaulich, Manuel, Pohl, Christian, Münch, Christian
Publicado 2022

FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels

por Elcocks, Hannah, Brazel, Ailbhe J, McCarron, Katy R, Kaulich, Manuel, Husnjak, Koraljka, Mortiboys, Heather, Clague, Michael J, Urbé, Sylvie
Publicado 2023

A Cdk4/6-dependent phosphorylation gradient regulates the early to late G1 phase transition

por Kaulich, Manuel, Link, Verena M., Lapek, John D., Lee, Yeon J., Glass, Christopher K., Gonzalez, David J., Dowdy, Steven F.
Publicado 2021

ERK5 modulates IL-6 secretion and contributes to tumor-induced immune suppression

por Riegel, Kristina, Yurugi, Hajime, Schlöder, Janine, Jonuleit, Helmut, Kaulich, Manuel, Kirschner, Friederike, Arnold-Schild, Danielle, Tenzer, Stefan, Schild, Hansjörg, Rajalingam, Krishnaraj
Publicado 2021

S105: CLONAL DIFFERENTIATION TRAJECTORIES OF ADULT ACUTE LYMPHOBLASTIC LEUKEMIA AT SINGLE CELL LEVEL

por Geßner, Alec, Jolly, Adrien, Sijmonsma, Tjeerd, Yu, Weijia, Abou-El-Ardat, Khalil, Kaulich, Manuel, Guenther, Stefan, Lang, Fabian, Buettner, Florian, Rieger, Michael
Publicado 2023

The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions

por Eichler, Madeleine, Distler, Ute, Nasrullah, Usman, Krishnan, Aswini, Kaulich, Manuel, Husnjak, Koraljka, Eberhardt, Wolfgang, Rajalingam, Krishnaraj, Tenzer, Stefan, Pfeilschifter, Josef, Imre, Gergely
Publicado 2022

P447: DECIPHERING THE MITOPHAGY RECEPTOR NETWORK IDENTIFIES A CRUCIAL ROLE FOR OPTINEURIN IN ACUTE MYELOID LEUKEMIA

por Meyer, Laura, Koschade, Sebastian, Vischedyk, Jonas, Thölken, Marlyn, Gubas, Andrea, Wegner, Martin, Basoglu, Marion, Knapp, Stefan, Kaulich, Manuel, Eimer, Stefan, Shaid, Shabnam, Brandts, Christian
Publicado 2023

Integrative analysis of epigenetics data identifies gene-specific regulatory elements

por Schmidt, Florian, Marx, Alexander, Baumgarten, Nina, Hebel, Marie, Wegner, Martin, Kaulich, Manuel, Leisegang, Matthias S, Brandes, Ralf P, Göke, Jonathan, Vreeken, Jilles, Schulz, Marcel H
Publicado 2021

A novel TPR–BEN domain interaction mediates PICH–BEND3 association

por Pitchai, Ganesha P., Kaulich, Manuel, Bizard, Anna H., Mesa, Pablo, Yao, Qi, Sarlos, Kata, Streicher, Werner W., Nigg, Erich A., Montoya, Guillermo, Hickson, Ian D.
Publicado 2017

53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration

por Meitinger, Franz, Anzola, John V., Kaulich, Manuel, Richardson, Amelia, Stender, Joshua D., Benner, Christopher, Glass, Christopher K., Dowdy, Steven F., Desai, Arshad, Shiau, Andrew K., Oegema, Karen
Publicado 2016

ERK3/MAPK6 controls IL-8 production and chemotaxis

por Bogucka, Katarzyna, Pompaiah, Malvika, Marini, Federico, Binder, Harald, Harms, Gregory, Kaulich, Manuel, Klein, Matthias, Michel, Christian, Radsak, Markus P, Rosigkeit, Sebastian, Grimminger, Peter, Schild, Hansjörg, Rajalingam, Krishnaraj
Publicado 2020

Optimized metrics for orthogonal combinatorial CRISPR screens

por Cetin, Ronay, Wegner, Martin, Luwisch, Leah, Saud, Sarada, Achmedov, Tatjana, Süsser, Sebastian, Vera-Guapi, Antonella, Müller, Konstantin, Matthess, Yves, Quandt, Eva, Schaubeck, Simone, Beisel, Chase L., Kaulich, Manuel
Publicado 2023