Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vacci...

por Kaumaya, Pravin T. P., Guo, Linlin, Overholser, Jay, Penichet, Manuel L., Bekaii-Saab, Tanios
Publicado 2020

Preclinical Studies of a Novel Human PD-1 B-Cell Peptide Cancer Vaccine PD1-Vaxx From BALB/c Mice to Beagle Dogs and to Non-Human Primates (Cynomolgus Monkeys)

por Guo, Linlin, Overholser, Jay, Good, Anthony J., Ede, Nicholas J., Kaumaya, Pravin T. P.
Publicado 2022

A newly discovered PD-L1 B-cell epitope peptide vaccine (PDL1-Vaxx) exhibits potent immune responses and effective anti-tumor immunity in multiple syngeneic mice models and (synerg...

por Guo, Linlin, Overholser, Jay, Darby, Heather, Ede, Nicholas J., Kaumaya, Pravin T.P
Publicado 2022

Combined vaccination with HER-2 peptide followed by therapy with VEGF peptide mimics exerts effective anti-tumor and anti-angiogenic effects in vitro and in vivo

por Foy, Kevin C., Miller, Megan J., Moldovan, Nicanor, Carson, William E., Kaumaya, Pravin T. P.
Publicado 2012

Immunotherapy with HER-2 and VEGF peptide mimics plus metronomic paclitaxel causes superior antineoplastic effects in transplantable and transgenic mouse models of human breast can...

por Foy, Kevin C., Miller, Megan J., Moldovan, Nicanor, Bozanovic, Tatjana, Carson, William E., Kaumaya, Pravin T. P.
Publicado 2012

Anti-Tumor Effects of Peptide Therapeutic and Peptide Vaccine Antibody Co-targeting HER-1 and HER-2 in Esophageal Cancer (EC) and HER-1 and IGF-1R in Triple-Negative Breast Cancer...

por Overholser, Jay, Ambegaokar, Kristen Henkins, Eze, Siobhan M., Sanabria-Figueroa, Eduardo, Nahta, Rita, Bekaii-Saab, Tanios, Kaumaya, Pravin T.P.
Publicado 2015