Protein Kinases and Neurodegenerative Diseases

por Kawahata, Ichiro, Fukunaga, Kohji
Publicado 2023

Degradation of Tyrosine Hydroxylase by the Ubiquitin-Proteasome System in the Pathogenesis of Parkinson’s Disease and Dopa-Responsive Dystonia

por Kawahata, Ichiro, Fukunaga, Kohji
Publicado 2020

Fatty Acid Binding Protein 5 Mediates Cell Death by Psychosine Exposure through Mitochondrial Macropores Formation in Oligodendrocytes

por Cheng, An, Kawahata, Ichiro, Fukunaga, Kohji
Publicado 2020

The Role of CaMKII and ERK Signaling in Addiction

por Jia, Wenbin, Kawahata, Ichiro, Cheng, An, Fukunaga, Kohji
Publicado 2021

Impact of Fatty Acid-Binding Proteins in α-Synuclein-Induced Mitochondrial Injury in Synucleinopathy

por Cheng, An, Jia, Wenbin, Kawahata, Ichiro, Fukunaga, Kohji
Publicado 2021

A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models

por Cheng, An, Jia, Wenbin, Kawahata, Ichiro, Fukunaga, Kohji
Publicado 2021

Pathogenic Impact of α-Synuclein Phosphorylation and Its Kinases in α-Synucleinopathies

por Kawahata, Ichiro, Finkelstein, David I., Fukunaga, Kohji
Publicado 2022

Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP(+)-Induced Mitochondrial Dysfunction in Cultured Dopaminergic Neurons

por Kawahata, Ichiro, Bousset, Luc, Melki, Ronald, Fukunaga, Kohji
Publicado 2019

T-Type Ca(2+) Enhancer SAK3 Activates CaMKII and Proteasome Activities in Lewy Body Dementia Mice Model

por Xu, Jing, Kawahata, Ichiro, Izumi, Hisanao, Fukunaga, Kohji
Publicado 2021

Epidermal Fatty Acid-Binding Protein 5 (FABP5) Involvement in Alpha-Synuclein-Induced Mitochondrial Injury under Oxidative Stress

por Wang, Yifei, Shinoda, Yasuharu, Cheng, An, Kawahata, Ichiro, Fukunaga, Kohji
Publicado 2021

Using Fatty Acid-Binding Proteins as Potential Biomarkers to Discriminate between Parkinson’s Disease and Dementia with Lewy Bodies: Exploration of a Novel Technique

por Kawahata, Ichiro, Sekimori, Tomoki, Oizumi, Hideki, Takeda, Atsushi, Fukunaga, Kohji
Publicado 2023

Amelioration of Nicotine-Induced Conditioned Place Preference Behaviors in Mice by an FABP3 Inhibitor

por Jia, Wenbin, Kawahata, Ichiro, Cheng, An, Sasaki, Takuya, Sasaoka, Toshikuni, Fukunaga, Kohji
Publicado 2023

SAK3 Administration Improves Spine Abnormalities and Cognitive Deficits in App(NL-G-F/NL-G-F) Knock-in Mice by Increasing Proteasome Activity through CaMKII/Rpt6 Signaling

por Izumi, Hisanao, Kawahata, Ichiro, Shinoda, Yasuharu, Helmstetter, Fred J., Fukunaga, Kohji
Publicado 2020

Single Administration of the T-Type Calcium Channel Enhancer SAK3 Reduces Oxidative Stress and Improves Cognition in Olfactory Bulbectomized Mice

por Yuan, Dian, Cheng, An, Kawahata, Ichiro, Izumi, Hisanao, Xu, Jing, Fukunaga, Kohji
Publicado 2021

Fatty Acid-Binding Proteins: Their Roles in Ischemic Stroke and Potential as Drug Targets

por Guo, Qingyun, Kawahata, Ichiro, Cheng, An, Jia, Wenbin, Wang, Haoyang, Fukunaga, Kohji
Publicado 2022

Fatty acid-binding proteins 3 and 5 are involved in the initiation of mitochondrial damage in ischemic neurons

por Guo, Qingyun, Kawahata, Ichiro, Cheng, An, Wang, Haoyang, Jia, Wenbin, Yoshino, Hiroshi, Fukunaga, Kohji
Publicado 2022

α‐Synuclein decoy peptide protects mice against α‐synuclein‐induced memory loss

por Guo, Qingyun, Kawahata, Ichiro, Jia, Wenbin, Wang, Haoyang, Cheng, An, Yabuki, Yasushi, Shioda, Norifumi, Fukunaga, Kohji
Publicado 2023

Fatty Acid-Binding Proteins Aggravate Cerebral Ischemia-Reperfusion Injury in Mice

por Guo, Qingyun, Kawahata, Ichiro, Degawa, Tomohide, Ikeda-Matsuo, Yuri, Sun, Meiling, Han, Feng, Fukunaga, Kohji
Publicado 2021

Case Report: Guitarist’s cramp as the initial manifestation of dopa-responsive dystonia with a novel heterozygous GCH1 mutation

por Hasegawa, Takafumi, Hosaka, Tatsuhiko, Harada, Ryuhei, Kawahata, Ichiro, Hoshino, Kyoko, Sugeno, Naoto, Kikuchi, Akio, Aoki, Masashi
Publicado 2021

Fatty Acid Binding Protein 3 Enhances the Spreading and Toxicity of α-Synuclein in Mouse Brain

por Yabuki, Yasushi, Matsuo, Kazuya, Kawahata, Ichiro, Fukui, Naoya, Mizobata, Tomohiro, Kawata, Yasushi, Owada, Yuji, Shioda, Norifumi, Fukunaga, Kohji
Publicado 2020