Asymmetric nature of two subunits of RAD18, a RING-type ubiquitin ligase E3, in the human RAD6A–RAD18 ternary complex

por Masuda, Yuji, Suzuki, Miki, Kawai, Hidehiko, Suzuki, Fumio, Kamiya, Kenji
Publicado 2012

Preferential digestion of PCNA-ubiquitin and p53-ubiquitin linkages by USP7 to remove polyubiquitin chains from substrates

por Masuda, Yuji, Kanao, Rie, Kawai, Hidehiko, Kukimoto, Iwao, Masutani, Chikahide
Publicado 2019

RFWD3 and translesion DNA polymerases contribute to PCNA modification–dependent DNA damage tolerance

por Kanao, Rie, Kawai, Hidehiko, Taniguchi, Toshiyasu, Takata, Minoru, Masutani, Chikahide
Publicado 2022

Mitochondrial reactive oxygen species perturb AKT/cyclin D1 cell cycle signaling via oxidative inactivation of PP2A in lowdose irradiated human fibroblasts

por Shimura, Tsutomu, Sasatani, Megumi, Kamiya, Kenji, Kawai, Hidehiko, Inaba, Yohei, Kunugita, Naoki
Publicado 2015

Metabolomic screening using ESI-FT MS identifies potential radiation-responsive molecules in mouse urine

por Iizuka, Daisuke, Yoshioka, Susumu, Kawai, Hidehiko, Izumi, Shunsuke, Suzuki, Fumio, Kamiya, Kenji
Publicado 2017

Constitutive Phosphorylation of Aurora-A on Ser51 Induces Its Stabilization and Consequent Overexpression in Cancer

por Kitajima, Shojiro, Kudo, Yasusei, Ogawa, Ikuko, Tatsuka, Masaaki, Kawai, Hidehiko, Pagano, Michele, Takata, Takashi
Publicado 2007

Low-Dose-Rate Irradiation Suppresses the Expression of Cell Cycle-Related Genes, Resulting in Modification of Sensitivity to Anti-Cancer Drugs

por Shimabukuro, Kiichi, Fukazawa, Takahiro, Kanai, Akinori, Kawai, Hidehiko, Mekata, Kengo, Hirohashi, Nobuyuki, Kakimoto, Naoya, Tanimoto, Keiji
Publicado 2022

Development of a versatile high-throughput mutagenesis assay with multiplexed short-read NGS using DNA-barcoded supF shuttle vector library amplified in E. coli

por Kawai, Hidehiko, Iwata, Ren, Ebi, Shungo, Sugihara, Ryusei, Masuda, Shogo, Fujiwara, Chiho, Kimura, Shingo, Kamiya, Hiroyuki
Publicado 2022

En bloc transfer of polyubiquitin chains to PCNA in vitro is mediated by two different human E2–E3 pairs

por Masuda, Yuji, Suzuki, Miki, Kawai, Hidehiko, Hishiki, Asami, Hashimoto, Hiroshi, Masutani, Chikahide, Hishida, Takashi, Suzuki, Fumio, Kamiya, Kenji
Publicado 2012

APC/C(Cdh1) is required for the termination of chromosomal passenger complex activity upon mitotic exit

por Tsunematsu, Takaaki, Arakaki, Rieko, Kawai, Hidehiko, Ruppert, Jan, Tsuneyama, Koichi, Ishimaru, Naozumi, Earnshaw, William C., Pagano, Michele, Kudo, Yasusei
Publicado 2020

Hepcidin-2 in mouse urine as a candidate radiation-responsive molecule

por Iizuka, Daisuke, Yoshioka, Susumu, Kawai, Hidehiko, Okazaki, Emi, Kiriyama, Keita, Izumi, Shunsuke, Nishimura, Mayumi, Shimada, Yoshiya, Kamiya, Kenji, Suzuki, Fumio
Publicado 2016

A Novel ATM/TP53/p21-Mediated Checkpoint Only Activated by Chronic γ-Irradiation

por Cao, Lili, Kawai, Hidehiko, Sasatani, Megumi, Iizuka, Daisuke, Masuda, Yuji, Inaba, Toshiya, Suzuki, Keiji, Ootsuyama, Akira, Umata, Toshiyuki, Kamiya, Kenji, Suzuki, Fumio
Publicado 2014

RAD18 Activates the G2/M Checkpoint through DNA Damage Signaling to Maintain Genome Integrity after Ionizing Radiation Exposure

por Sasatani, Megumi, Xu, Yanbin, Kawai, Hidehiko, Cao, Lili, Tateishi, Satoshi, Shimura, Tsutomu, Li, Jianxiang, Iizuka, Daisuke, Noda, Asao, Hamasaki, Kanya, Kusunoki, Yoichiro, Kamiya, Kenji
Publicado 2015

Hypertension and diabetes mellitus are associated with high FIB-4 index in a health checkup examination cohort without known liver disease

por Sato, Shunsuke, Kawai, Hidehiko, Sato, Sho, Iwasaki, Hirohiko, Omori, Masashi, Kita, Yuji, Ikeda, Yuji, Awatsu, Takahito, Murata, Ayato, Taniguchi, Gentaro, Shimada, Yuji, Genda, Takuya
Publicado 2022

Overexpression of Rev1 promotes the development of carcinogen-induced intestinal adenomas via accumulation of point mutation and suppression of apoptosis proportionally to the Rev1...

por Sasatani, Megumi, Xi, Yang, Kajimura, Junko, Kawamura, Toshiyuki, Piao, Jinlian, Masuda, Yuji, Honda, Hiroaki, Kubo, Kei, Mikamoto, Takahiro, Watanabe, Hiromitsu, Xu, Yanbin, Kawai, Hidehiko, Shimura, Tsutomu, Noda, Asao, Hamasaki, Kanya, Kusunoki, Yoichiro, Zaharieva, Elena Karamfilova, Kamiya, Kenji
Publicado 2017

Replication stress induces accumulation of FANCD2 at central region of large fragile genes

por Okamoto, Yusuke, Iwasaki, Watal M, Kugou, Kazuto, Takahashi, Kazuki K, Oda, Arisa, Sato, Koichi, Kobayashi, Wataru, Kawai, Hidehiko, Sakasai, Ryo, Takaori-Kondo, Akifumi, Yamamoto, Takashi, Kanemaki, Masato T, Taoka, Masato, Isobe, Toshiaki, Kurumizaka, Hitoshi, Innan, Hideki, Ohta, Kunihiro, Ishiai, Masamichi, Takata, Minoru
Publicado 2018

DDX41 coordinates RNA splicing and transcriptional elongation to prevent DNA replication stress in hematopoietic cells

por Shinriki, Satoru, Hirayama, Mayumi, Nagamachi, Akiko, Yokoyama, Akihiko, Kawamura, Takeshi, Kanai, Akinori, Kawai, Hidehiko, Iwakiri, Junichi, Liu, Rin, Maeshiro, Manabu, Tungalag, Saruul, Tasaki, Masayoshi, Ueda, Mitsuharu, Tomizawa, Kazuhito, Kataoka, Naoyuki, Ideue, Takashi, Suzuki, Yutaka, Asai, Kiyoshi, Tani, Tokio, Inaba, Toshiya, Matsui, Hirotaka
Publicado 2022