Tyrosyl–DNA phosphodiesterases: rescuing the genome from the risks of relaxation

por Kawale, Ajinkya S, Povirk, Lawrence F
Publicado 2018

Bloom helicase mediates formation of large single–stranded DNA loops during DNA end processing

por Xue, Chaoyou, Salunkhe, Sameer J., Tomimatsu, Nozomi, Kawale, Ajinkya S., Kwon, Youngho, Burma, Sandeep, Sung, Patrick, Greene, Eric C.
Publicado 2022

TDP1 suppresses mis-joining of radiomimetic DNA double-strand breaks and cooperates with Artemis to promote optimal nonhomologous end joining

por Kawale, Ajinkya S, Akopiants, Konstantin, Valerie, Kristoffer, Ruis, Brian, Hendrickson, Eric A, Huang, Shar-yin N, Pommier, Yves, Povirk, Lawrence F
Publicado 2018

Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death

por Jiang, Hui, Xue, Xiaoyu, Panda, Swarupa, Kawale, Ajinkya, Hooy, Richard M, Liang, Fengshan, Sohn, Jungsan, Sung, Patrick, Gekara, Nelson O
Publicado 2019

DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation

por Kwon, Youngho, Rösner, Heike, Zhao, Weixing, Selemenakis, Platon, He, Zhuoling, Kawale, Ajinkya S., Katz, Jeffrey N., Rogers, Cody M., Neal, Francisco E., Badamchi Shabestari, Aida, Petrosius, Valdemaras, Singh, Akhilesh K., Joel, Marina Z., Lu, Lucy, Holloway, Stephen P., Burma, Sandeep, Mukherjee, Bipasha, Hromas, Robert, Mazin, Alexander, Wiese, Claudia, Sørensen, Claus S., Sung, Patrick
Publicado 2023