Experimental method for haplotype phasing across the entire length of chromosome 21 in trisomy 21 cells using a chromosome elimination technique

por Wakita, Sachiko, Hara, Mari, Kitabatake, Yasuji, Kawatani, Keiji, Kurahashi, Hiroki, Hashizume, Ryotaro
Publicado 2022

A human isogenic iPSC-derived cell line panel identifies major regulators of aberrant astrocyte proliferation in Down syndrome

por Kawatani, Keiji, Nambara, Toshihiko, Nawa, Nobutoshi, Yoshimatsu, Hidetaka, Kusakabe, Haruna, Hirata, Katsuya, Tanave, Akira, Sumiyama, Kenta, Banno, Kimihiko, Taniguchi, Hidetoshi, Arahori, Hitomi, Ozono, Keiichi, Kitabatake, Yasuji
Publicado 2021

A Pair of Maternal Chromosomes Derived from Meiotic Nondisjunction in Trisomy 21 Affects Nuclear Architecture and Transcriptional Regulation

por Omori, Sayaka, Tanabe, Hideyuki, Banno, Kimihiko, Tsuji, Ayumi, Nawa, Nobutoshi, Hirata, Katsuya, Kawatani, Keiji, Kokubu, Chikara, Takeda, Junji, Taniguchi, Hidetoshi, Arahori, Hitomi, Wada, Kazuko, Kitabatake, Yasuji, Ozono, Keiichi
Publicado 2017

4-Phenylbutyrate ameliorates apoptotic neural cell death in Down syndrome by reducing protein aggregates

por Hirata, Katsuya, Nambara, Toshihiko, Kawatani, Keiji, Nawa, Nobutoshi, Yoshimatsu, Hidetaka, Kusakabe, Haruna, Banno, Kimihiko, Nishimura, Ken, Ohtaka, Manami, Nakanishi, Mahito, Taniguchi, Hidetoshi, Arahori, Hitomi, Wada, Kazuko, Ozono, Keiichi, Kitabatake, Yasuji
Publicado 2020

Elimination of protein aggregates prevents premature senescence in human trisomy 21 fibroblasts

por Nawa, Nobutoshi, Hirata, Katsuya, Kawatani, Keiji, Nambara, Toshihiko, Omori, Sayaka, Banno, Kimihiko, Kokubu, Chikara, Takeda, Junji, Nishimura, Ken, Ohtaka, Manami, Nakanishi, Mahito, Okuzaki, Daisuke, Taniguchi, Hidetoshi, Arahori, Hitomi, Wada, Kazuko, Kitabatake, Yasuji, Ozono, Keiichi
Publicado 2019

LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4

por Oue, Hiroshi, Yamazaki, Yu, Qiao, Wenhui, Yuanxin, Chen, Ren, Yingxue, Kurti, Aishe, Shue, Francis, Parsons, Tammee M., Perkerson, Ralph B., Kawatani, Keiji, Wang, Ni, Starling, Skylar C., Roy, Bhaskar, Mosneag, Ioana-Emilia, Aikawa, Tomonori, Holm, Marie-Louise, Liu, Chia-Chen, Inoue, Yasuteru, Sullivan, Patrick M., Asmann, Yan W., Kim, Betty Y.S., Bu, Guojun, Kanekiyo, Takahisa
Publicado 2023