Progranulin gene delivery reduces plaque burden and synaptic atrophy in a mouse model of Alzheimer's disease

por Van Kampen, Jackalina M., Kay, Denis G.
Publicado 2017

Progranulin Gene Delivery Protects Dopaminergic Neurons in a Mouse Model of Parkinson’s Disease

por Van Kampen, Jackalina M., Baranowski, David, Kay, Denis G.
Publicado 2014

Neurotrophic effects of progranulin in vivo in reversing motor neuron defects caused by over or under expression of TDP-43 or FUS

por Chitramuthu, Babykumari P., Kay, Denis G., Bateman, Andrew, Bennett, Hugh P. J.
Publicado 2017

Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1

por Chitramuthu, Babykumari P, Baranowski, David C, Kay, Denis G, Bateman, Andrew, Bennett, Hugh PJ
Publicado 2010

The Progressive BSSG Rat Model of Parkinson's: Recapitulating Multiple Key Features of the Human Disease

por Van Kampen, Jackalina M., Baranowski, David C., Robertson, Harold A., Shaw, Christopher A., Kay, Denis G.
Publicado 2015

First in human study with a prodrug of galantamine: Improved benefit-risk ratio?

por Baakman, Anne C., 't Hart, Ellen, Kay, Denis G., Stevens, Jasper, Klaassen, Erica S., Maelicke, Alfred, Groeneveld, Geert J.
Publicado 2016

Safety, pharmacokinetics, and pharmacodynamics of Gln‐1062, a prodrug of galantamine

por Bakker, Charlotte, van der Aart, Jasper, Hart, Ellen P., Klaassen, Erica S., Bergmann, Kirsten R., van Esdonk, Michiel J., Kay, Denis G., Groeneveld, Geert Jan
Publicado 2020

Progranulin is expressed within motor neurons and promotes neuronal cell survival

por Ryan, Cara L, Baranowski, David C, Chitramuthu, Babykumari P, Malik, Suneil, Li, Zhi, Cao, Mingju, Minotti, Sandra, Durham, Heather D, Kay, Denis G, Shaw, Christopher A, Bennett, Hugh PJ, Bateman, Andrew
Publicado 2009