Gastrectomy with Roux-en-Y reconstruction as a lean model of bariatric surgery()()

por Roberts, Geoffrey P., Kay, Richard G., Howard, James, Hardwick, Richard H., Reimann, Frank, Gribble, Fiona M.
Publicado 2018

Peptidomic analysis of endogenous plasma peptides from patients with pancreatic neuroendocrine tumours

por Kay, Richard G., Challis, Benjamin G., Casey, Ruth T., Roberts, Geoffrey P., Meek, Claire L., Reimann, Frank, Gribble, Fiona M.
Publicado 2018

LC-MS/MS based detection of circulating proinsulin derived peptides in patients with altered pancreatic beta cell function

por Foreman, Rachel E, Meek, Claire L, Roberts, Geoffrey P, George, Amy L, Reimann, Frank, Gribble, Fiona M, Kay, Richard G
Publicado 2022

Single-cell RNA-sequencing reveals a distinct population of proglucagon-expressing cells specific to the mouse upper small intestine

por Glass, Leslie L., Calero-Nieto, Fernando J., Jawaid, Wajid, Larraufie, Pierre, Kay, Richard G., Göttgens, Berthold, Reimann, Frank, Gribble, Fiona M.
Publicado 2017

Increased C-Peptide Immunoreactivity in Insulin Autoimmune Syndrome (Hirata Disease) Due to High Molecular Weight Proinsulin

por Kay, Richard G, Barker, Peter, Burling, Keith, Cohen, Mark, Halsall, David, Reimann, Frank, Gribble, Fiona M, Semple, Robert K, Church, David
Publicado 2021

In vitro metabolism of synthetic Elabela/Toddler (ELA-32) peptide in human plasma and kidney homogenates analyzed with mass spectrometry and validation of endogenous peptide quanti...

por Nyimanu, Duuamene, Kay, Richard G., Kuc, Rhoda E., Brown, Alastair J.H., Gribble, Fiona M., Maguire, Janet J., Davenport, Anthony P.
Publicado 2021

Identification of Structural and Molecular Signatures Mediating Adaptive Changes in the Mouse Kidney in Response to Pregnancy

por Lopez-Tello, Jorge, Jimenez-Martinez, Maria Angeles, Salazar-Petres, Esteban, Patel, Ritik, George, Amy L., Kay, Richard G., Sferruzzi-Perri, Amanda N.
Publicado 2022

Optimized LC-MS/MS Method for the Detection of ppCCK(21–44): A Surrogate to Monitor Human Cholecystokinin Secretion

por Foreman, Rachel E., Miedzybrodzka, Emily L., Eiríksson, Finnur Freyr, Thorsteinsdóttir, Margrét, Bannon, Christopher, Wheller, Robert, Reimann, Frank, Gribble, Fiona M., Kay, Richard G.
Publicado 2023

Selective stimulation of colonic L cells improves metabolic outcomes in mice

por Lewis, Jo E., Miedzybrodzka, Emily L., Foreman, Rachel E., Woodward, Orla R. M., Kay, Richard G., Goldspink, Deborah A., Gribble, Fiona M., Reimann, Frank
Publicado 2020

The Human and Mouse Islet Peptidome: Effects of Obesity and Type 2 Diabetes, and Assessment of Intraislet Production of Glucagon-like Peptide-1

por Galvin, Sam G., Kay, Richard G., Foreman, Rachel, Larraufie, Pierre, Meek, Claire L., Biggs, Emma, Ravn, Peter, Jermutus, Lutz, Reimann, Frank, Gribble, Fiona M.
Publicado 2021

Organoid Sample Preparation and Extraction for LC-MS Peptidomics

por Miedzybrodzka, Emily L., Foreman, Rachel E., Galvin, Sam G., Larraufie, Pierre, George, Amy L., Goldspink, Deborah A., Reimann, Frank, Gribble, Fiona M., Kay, Richard G.
Publicado 2020

Labeling and Characterization of Human GLP-1-Secreting L-cells in Primary Ileal Organoid Culture

por Goldspink, Deborah A., Lu, Van B., Miedzybrodzka, Emily L., Smith, Christopher A., Foreman, Rachel E., Billing, Lawrence J., Kay, Richard G., Reimann, Frank, Gribble, Fiona M.
Publicado 2020

Single cell transcriptomic profiling of large intestinal enteroendocrine cells in mice – Identification of selective stimuli for insulin-like peptide-5 and glucagon-like peptide-1...

por Billing, Lawrence J., Larraufie, Pierre, Lewis, Jo, Leiter, Andrew, Li, Joyce, Lam, Brian, Yeo, Giles SH., Goldspink, Deborah A., Kay, Richard G., Gribble, Fiona M., Reimann, Frank
Publicado 2019

Development and validation of an LC-MS/MS method for detection and quantification of in vivo derived metabolites of [Pyr(1)]apelin-13 in humans

por Nyimanu, Duuamene, Kay, Richard G., Sulentic, Petra, Kuc, Rhoda E., Ambery, Philip, Jermutus, Lutz, Reimann, Frank, Gribble, Fiona M., Cheriyan, Joseph, Maguire, Janet J., Davenport, Anthony P.
Publicado 2019

Stimulation of motilin secretion by bile, free fatty acids, and acidification in human duodenal organoids

por Miedzybrodzka, Emily L., Foreman, Rachel E., Lu, Van B., George, Amy L., Smith, Christopher A., Larraufie, Pierre, Kay, Richard G., Goldspink, Deborah A., Reimann, Frank, Gribble, Fiona M.
Publicado 2021

Placental secretome characterization identifies candidates for pregnancy complications

por Napso, Tina, Zhao, Xiaohui, Lligoña, Marta Ibañez, Sandovici, Ionel, Kay, Richard G., George, Amy L., Gribble, Fiona M., Reimann, Frank, Meek, Claire L., Hamilton, Russell S., Sferruzzi-Perri, Amanda N.
Publicado 2021

Dual binding motifs underpin the hierarchical association of perilipins1–3 with lipid droplets

por Ajjaji, Dalila, Ben M'barek, Kalthoum, Mimmack, Michael L., England, Cheryl, Herscovitz, Haya, Dong, Liang, Kay, Richard G., Patel, Satish, Saudek, Vladimir, Small, Donald M., Savage, David B., Thiam, Abdou Rachid
Publicado 2019

Co-storage and release of insulin-like peptide-5, glucagon-like peptide-1 and peptideYY from murine and human colonic enteroendocrine cells

por Billing, Lawrence J., Smith, Christopher A., Larraufie, Pierre, Goldspink, Deborah A., Galvin, Sam, Kay, Richard G., Howe, Jonathan D., Walker, Ryan, Pruna, Mihai, Glass, Leslie, Pais, Ramona, Gribble, Fiona M., Reimann, Frank
Publicado 2018

Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis

por Kirwan, Peter, Kay, Richard G., Brouwers, Bas, Herranz-Pérez, Vicente, Jura, Magdalena, Larraufie, Pierre, Jerber, Julie, Pembroke, Jason, Bartels, Theresa, White, Anne, Gribble, Fiona M., Reimann, Frank, Farooqi, I. Sadaf, O'Rahilly, Stephen, Merkle, Florian T.
Publicado 2018

Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery

por Larraufie, Pierre, Roberts, Geoffrey P., McGavigan, Anne K., Kay, Richard G., Li, Joyce, Leiter, Andrew, Melvin, Audrey, Biggs, Emma K., Ravn, Peter, Davy, Kathleen, Hornigold, David C., Yeo, Giles S.H., Hardwick, Richard H., Reimann, Frank, Gribble, Fiona M.
Publicado 2019