The Prevalence of Rhesus-Negative Blood Group Among Patient With Small Cell Lung Cancer and Analysis of Its Effect on Overall Survival

por Biswas, Abhishek, Jiang, Yue, Li, Danmeng, Mehta, Hiren J., Kaye, Frederic
Publicado 2018

Ephrin-A1 inhibits NSCLC tumor growth via induction of Cdx-2 a tumor suppressor gene

por Sukka-Ganesh, Bhagyalaxmi, Mohammed, Kamal A, Kaye, Frederic, Goldberg, Eugene P, Nasreen, Najmunnisa
Publicado 2012

Targeting Notch and EGFR signaling in human mucoepidermoid carcinoma

por Ni, Wei, Chen, Zirong, Zhou, Xin, Yang, Rongqiang, Yu, Mu, Lu, Jianrong, Kaye, Frederic J., Wu, Lizi
Publicado 2021

CRTC1-MAML2 fusion-induced lncRNA LINC00473 expression maintains the growth and survival of human mucoepidermoid carcinoma cells

por Chen, Zirong, Lin, Shuibin, Li, Jian-Liang, Ni, Wei, Guo, Ruifeng, Lu, Jianrong, Kaye, Frederic J., Wu, Lizi
Publicado 2018

Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer

por Komiya, Takefumi, Coxon, Amy, Park, Yoonsoo, Chen, Wei-dong, Zajac-Kaye, Maria, Meltzer, Paul, Karpova, Tatiana, Kaye, Frederic J.
Publicado 2009

Disparities Contributing to Late-Stage Diagnosis of Lung, Colorectal, Breast, and Cervical Cancers: Rural and Urban Poverty in Florida

por Hall, Jaclyn M., Mkuu, Rahma S., Cho, Hee Deok, Woodard, Jennifer N., Kaye, Frederic J., Bian, Jiang, Shenkman, Elizabeth A., Guo, Yi
Publicado 2023

TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background

por Guijarro, Maria V., Nawab, Akbar, Dib, Peter, Burkett, Sandra, Luo, Xiaoping, Feely, Michael, Nasri, Elham, Seifert, Robert P., Kaye, Frederic J., Zajac-Kaye, Maria
Publicado 2023

CDK4/6 inhibition stabilizes disease in patients with p16-null non-small cell lung cancer and is synergistic with mTOR inhibition

por Gopalan, Priya K., Villegas, Andres Gordillo, Cao, Chunxia, Pinder-Schenck, Mary, Chiappori, Alberto, Hou, Wei, Zajac-Kaye, Maria, Ivey, Alison M., Kaye, Frederic J.
Publicado 2018

Reducing Chemotherapy-Induced DNA Damage via nAChR-Mediated Redox Reprograming—A New Mechanism for SCLC Chemoresistance Boosted by Nicotine

por Wang, Yuzhi, Bian, Tengfei, Song, Lina, Jiang, Yunhan, Huo, Zhiguang, Salloum, Ramzi G., Warren, Graham W., Kaye, Frederic J., Fujioka, Naomi, Jin, Lingtao, Xing, Chengguo
Publicado 2022

Dependency of human and murine LKB1-inactivated lung cancer on aberrant CRTC-CREB activation

por Zhou, Xin, Li, Jennifer W, Chen, Zirong, Ni, Wei, Li, Xuehui, Yang, Rongqiang, Shen, Huangxuan, Liu, Jian, DeMayo, Francesco J, Lu, Jianrong, Kaye, Frederic J, Wu, Lizi
Publicado 2021

BCL-X(L) PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRAS(G12C)-mutated cancers

por Khan, Sajid, Wiegand, Janet, Zhang, Peiyi, Hu, Wanyi, Thummuri, Dinesh, Budamagunta, Vivekananda, Hua, Nan, Jin, Lingtao, Allegra, Carmen J., Kopetz, Scott E., Zajac-Kaye, Maria, Kaye, Frederic J., Zheng, Guangrong, Zhou, Daohong
Publicado 2022

A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets

por Gao, Ruli, Cao, Chunxia, Zhang, Min, Lopez, Maria-Cecilia, Yan, Yuanqing, Chen, Zirong, Mitani, Yoshitsugu, Zhang, Li, Zajac-Kaye, Maria, Liu, Bin, Wu, Lizi, Renne, Rolf, Baker, Henry V., El-Naggar, Adel, Kaye, Frederic J.
Publicado 2014

Personalised Lung Cancer Screening (PLuS) study to assess the importance of coexisting chronic conditions to clinical practice and policy: protocol for a multicentre observational...

por Braithwaite, Dejana, Karanth, Shama D, Slatore, Christopher G, Zhang, Dongyu, Bian, Jiang, Meza, Rafael, Jeon, Jihyoun, Tammemagi, Martin, Schabath, Mattthew, Wheeler, Meghann, Guo, Yi, Hochhegger, Bruno, Kaye, Frederic J, Silvestri, Gerard A, Gould, Michael K
Publicado 2022

The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma

por Chen, Zirong, Ni, Wei, Li, Jian-Liang, Lin, Shuibin, Zhou, Xin, Sun, Yuping, Li, Jennifer W., Leon, Marino E., Hurtado, Maria D., Zolotukhin, Sergei, Liu, Chen, Lu, Jianrong, Griffin, James D., Kaye, Frederic J., Wu, Lizi
Publicado 2021

Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival

por Vijayakurup, Vinod, Maeng, Kyungah, Lee, Hye Seung, Meyer, Benjamin, Burkett, Sandra, Nawab, Akbar, Dougherty, Michael W., Jobin, Christian, Mahmud, Iqbal, Garrett, Timothy J., Feely, Michael, Lee, Kyoung Bun, Kaye, Frederic J., Guijarro, Maria V., Zajac-Kaye, Maria
Publicado 2022

Co-targeting BCL-X(L) and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

por Khan, Sajid, Kellish, Patrick, Connis, Nick, Thummuri, Dinesh, Wiegand, Janet, Zhang, Peiyi, Zhang, Xuan, Budamagunta, Vivekananda, Hua, Nan, Yang, Yang, De, Umasankar, Jin, Lingtao, Zhang, Weizhou, Zheng, Guangrong, Hromas, Robert, Hann, Christine, Zajac-Kaye, Maria, Kaye, Frederic J., Zhou, Daohong
Publicado 2023

First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival

por Guijarro, Maria V., Kellish, Patrick C., Dib, Peter E., Paciaroni, Nicholas G., Nawab, Akbar, Andring, Jacob, Kulemina, Lidia, Borrero, Nicholas V., Modenutti, Carlos, Feely, Michael, Nasri, Elham, Seifert, Robert P., Luo, Xiaoping, Bennett, Richard L., Shabashvili, Daniil, Licht, Jonathan D., McKenna, Robert, Roitberg, Adrian, Huigens, Robert W., Kaye, Frederic J., Zajac-Kaye, Maria
Publicado 2023

The landscape of somatic copy-number alteration across human cancers

por Beroukhim, Rameen, Mermel, Craig H., Porter, Dale, Wei, Guo, Raychaudhuri, Soumya, Donovan, Jerry, Barretina, Jordi, Boehm, Jesse S., Dobson, Jennifer, Urashima, Mitsuyoshi, Mc Henry, Kevin T., Pinchback, Reid M., Ligon, Azra H., Cho, Yoon-Jae, Haery, Leila, Greulich, Heidi, Reich, Michael, Winckler, Wendy, Lawrence, Michael S., Weir, Barbara A., Tanaka, Kumiko E., Chiang, Derek Y., Bass, Adam J., Loo, Alice, Hoffman, Carter, Prensner, John, Liefeld, Ted, Gao, Qing, Yecies, Derek, Signoretti, Sabina, Maher, Elizabeth, Kaye, Frederic J., Sasaki, Hidefumi, Tepper, Joel E., Fletcher, Jonathan A., Tabernero, Josep, Baselga, Jose, Tsao, Ming-Sound, DeMichelis, Francesca, Rubin, Mark A., Janne, Pasi A., Daly, Mark J., Nucera, Carmelo, Levine, Ross L., Ebert, Benjamin L., Gabriel, Stacey, Rustgi, Anil K., Antonescu, Cristina R., Ladanyi, Marc, Letai, Anthony, Garraway, Levi A., Loda, Massimo, Beer, David G., True, Lawrence D., Okamoto, Aikou, Pomeroy, Scott L., Singer, Samuel, Golub, Todd R., Lander, Eric S., Getz, Gad, Sellers, William R., Meyerson, Matthew
Publicado 2010