Coevolving residues inform protein dynamics profiles and disease susceptibility of nSNVs

por Butler, Brandon M., Kazan, I. Can, Kumar, Avishek, Ozkan, S. Banu
Publicado 2018

The Role of Rigid Residues in Modulating TEM-1 β-Lactamase Function and Thermostability

por Kolbaba-Kartchner, Bethany, Kazan, I. Can, Mills, Jeremy H., Ozkan, S. Banu
Publicado 2021

Design of novel cyanovirin-N variants by modulation of binding dynamics through distal mutations

por Kazan, I Can, Sharma, Prerna, Rahman, Mohammad Imtiazur, Bobkov, Andrey, Fromme, Raimund, Ghirlanda, Giovanna, Ozkan, S Banu
Publicado 2022

Dynamic coupling of residues within proteins as a mechanistic foundation of many enigmatic pathogenic missense variants

por Ose, Nicholas J., Butler, Brandon M., Kumar, Avishek, Kazan, I. Can, Sanderford, Maxwell, Kumar, Sudhir, Ozkan, S. Banu
Publicado 2022

Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity

por Larrimore, Katherine E., Kazan, I. Can, Kannan, Latha, Kendle, R. Player, Jamal, Tameem, Barcus, Matthew, Bolia, Ashini, Brimijoin, Stephen, Zhan, Chang-Guo, Ozkan, S. Banu, Mor, Tsafrir S.
Publicado 2017

Author Correction: Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensiti...

por Larrimore, Katherine E., Kazan, I. Can, Kannan, Latha, Kendle, R. Player, Jamal, Tameem, Barcus, Matthew, Bolia, Ashini, Brimijoin, Stephen, Zhan, Chang-Guo, Ozkan, S. Banu, Mor, Tsafrir S.
Publicado 2018