Selective Inhibition of 2-Oxoglutarate and 2-Oxoadipate Dehydrogenases by the Phosphonate Analogs of Their 2-Oxo Acid Substrates

por Artiukhov, Artem V., Kazantsev, Alexey V., Lukashev, Nikolay V., Bellinzoni, Marco, Bunik, Victoria I.
Publicado 2021

Mitochondrial Impairment May Increase Cellular NAD(P)H: Resazurin Oxidoreductase Activity, Perturbing the NAD(P)H-Based Viability Assays

por Aleshin, Vasily A., Artiukhov, Artem V., Oppermann, Henry, Kazantsev, Alexey V., Lukashev, Nikolay V., Bunik, Victoria I.
Publicado 2015

pH-Sensitive Liposomes with Embedded 3-(isobutylamino)cholan-24-oic Acid: What Is the Possible Mechanism of Fast Cargo Release?

por Efimova, Anna A., Popov, Anton S., Kazantsev, Alexey V., Semenyuk, Pavel I., Le-Deygen, Irina M., Lukashev, Nikolay V., Yaroslavov, Alexander A.
Publicado 2023

Pd- and Cu-catalyzed approaches in the syntheses of new cholane aminoanthraquinone pincer-like ligands

por Lukashev, Nikolay V, Grabovyi, Gennadii A, Erzunov, Dmitry A, Kazantsev, Alexey V, Latyshev, Gennadij V, Averin, Alexei D, Beletskaya., Irina P
Publicado 2017

Increasing Inhibition of the Rat Brain 2-Oxoglutarate Dehydrogenase Decreases Glutathione Redox State, Elevating Anxiety and Perturbing Stress Adaptation

por Artiukhov, Artem V., Graf, Anastasia V., Kazantsev, Alexey V., Boyko, Alexandra I., Aleshin, Vasily A., Ksenofontov, Alexander L., Bunik, Victoria I.
Publicado 2022

Genome-Wide Transcriptome Profiling Provides Insight on Cholesterol and Lithocholate Degradation Mechanisms in Nocardioides simplex VKM Ac-2033D

por Shtratnikova, Victoria Y., Schelkunov, Mikhail I., Fokina, Victoria V., Bragin, Eugeny Y., Lobastova, Tatyana G., Shutov, Andrey A., Kazantsev, Alexey V., Donova, Marina V.
Publicado 2020

Administration of Phosphonate Inhibitors of Dehydrogenases of 2-Oxoglutarate and 2-Oxoadipate to Rats Elicits Target-Specific Metabolic and Physiological Responses

por Bunik, Victoria I., Artiukhov, Artem V., Kazantsev, Alexey V., Aleshin, Vasily A., Boyko, Alexandra I., Ksenofontov, Alexander L., Lukashev, Nikolay V., Graf, Anastasia V.
Publicado 2022

Phosphonate Inhibitors of Pyruvate Dehydrogenase Perturb Homeostasis of Amino Acids and Protein Succinylation in the Brain

por Artiukhov, Artem V., Aleshin, Vasily A., Karlina, Irina S., Kazantsev, Alexey V., Sibiryakina, Daria A., Ksenofontov, Alexander L., Lukashev, Nikolay V., Graf, Anastasia V., Bunik, Victoria I.
Publicado 2022

Synthetic analogues of 2-oxo acids discriminate metabolic contribution of the 2-oxoglutarate and 2-oxoadipate dehydrogenases in mammalian cells and tissues

por Artiukhov, Artem V., Grabarska, Aneta, Gumbarewicz, Ewelina, Aleshin, Vasily A., Kähne, Thilo, Obata, Toshihiro, Kazantsev, Alexey V., Lukashev, Nikolay V., Stepulak, Andrzej, Fernie, Alisdair R., Bunik, Victoria I.
Publicado 2020