A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

por Martin-Gayo, Enrique, Cole, Michael B., Kolb, Kellie E., Ouyang, Zhengyu, Cronin, Jacqueline, Kazer, Samuel W., Ordovas-Montanes, Jose, Lichterfeld, Mathias, Walker, Bruce D., Yosef, Nir, Shalek, Alex K., Yu, Xu G.
Publicado 2018

A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages

por Kimmerling, Robert J., Lee Szeto, Gregory, Li, Jennifer W., Genshaft, Alex S., Kazer, Samuel W., Payer, Kristofor R., de Riba Borrajo, Jacob, Blainey, Paul C., Irvine, Darrell J., Shalek, Alex K., Manalis, Scott R.
Publicado 2016

A Single Human V(H)-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood

por Sangesland, Maya, Yousif, Ashraf S., Ronsard, Larance, Kazer, Samuel W., Zhu, Alex Lee, Gatter, G. James, Hayward, Matthew R., Barnes, Ralston M., Quirindongo-Crespo, Maricel, Rohrer, Daniel, Lonberg, Nils, Kwon, Douglas, Shalek, Alex K., Lingwood, Daniel
Publicado 2020

Translational Studies Using the MALT1 Inhibitor (S)-Mepazine to Induce Treg Fragility and Potentiate Immune Checkpoint Therapy in Cancer

por Di Pilato, Mauro, Gao, Yun, Sun, Yi, Fu, Amina, Grass, Carina, Seeholzer, Thomas, Feederle, Regina, Mazo, Irina, Kazer, Samuel W., Litchfield, Kevin, von Andrian, Ulrich H., Mempel, Thorsten R., Jenkins, Russell W., Krappmann, Daniel, Keller, Peter
Publicado 2023

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

por Roider, Julia, Maehara, Takashi, Ngoepe, Abigail, Ramsuran, Duran, Muenchhoff, Maximilian, Adland, Emily, Aicher, Toby, Kazer, Samuel W., Jooste, Pieter, Karim, Farina, Kuhn, Warren, Shalek, Alex K., Ndung'u, Thumbi, Morris, Lynn, Moore, Penny L., Pillai, Shiv, Kløverpris, Henrik, Goulder, Philip, Leslie, Alasdair
Publicado 2018

Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy

por Singh, Alveera, Kazer, Samuel W., Roider, Julia, Krista, Kami C., Millar, Jane, Asowata, Osaretin E., Ngoepe, Abigail, Ramsuran, Duran, Fardoos, Rabiah, Ardain, Amanda, Muenchhoff, Maximilian, Kuhn, Warren, Karim, Farina, Ndung’u, Thumbi, Shalek, Alex K., Goulder, Philip, Leslie, Alasdair, Kløverpris, Henrik N.
Publicado 2020

MR1-Restricted MAIT Cells From The Human Lung Mucosal Surface Have Distinct Phenotypic, Functional, and Transcriptomic Features That Are Preserved in HIV Infection

por Khuzwayo, Sharon, Mthembu, Maphe, Meermeier, Erin W., Prakadan, Sanjay M., Kazer, Samuel W., Bassett, Thierry, Nyamande, Kennedy, Khan, Dilshaad Fakey, Maharaj, Priya, Mitha, Mohammed, Suleman, Moosa, Mhlane, Zoey, Ramjit, Dirhona, Karim, Farina, Shalek, Alex K., Lewinsohn, David M., Ndung’u, Thumbi, Wong, Emily B.
Publicado 2021

Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

por Sanjuan Nandin, Irene, Fong, Carol, Deantonio, Cecilia, Torreno-Pina, Juan A., Pecetta, Simone, Maldonado, Paula, Gasparrini, Francesca, Ordovas-Montanes, Jose, Kazer, Samuel W., Kjaer, Svend, Borley, Daryl W., Nair, Usha, Coleman, Julia A., Lingwood, Daniel, Shalek, Alex K., Meffre, Eric, Poignard, Pascal, Burton, Dennis R., Batista, Facundo D.
Publicado 2017

Correction: Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

por Nandin, Irene Sanjuan, Fong, Carol, Deantonio, Cecilia, Torreno-Pina, Juan A., Pecetta, Simone, Maldonado, Paula, Gasparrini, Francesca, Ordovas-Montanes, Jose, Kazer, Samuel W., Kjaer, Svend, Borley, Daryl W., Nair, Usha, Coleman, Julia A., Lingwood, Daniel, Shalek, Alex K., Meffre, Eric, Poignard, Pascal, Burton, Dennis R., Batista, Facundo D.
Publicado 2017

Allergic inflammatory memory in human respiratory epithelial progenitor cells

por Ordovas-Montanes, Jose, Dwyer, Daniel F., Nyquist, Sarah K., Buchheit, Kathleen M., Vukovic, Marko, Deb, Chaarushena, Wadsworth, Marc H., Hughes, Travis K., Kazer, Samuel W., Yoshimoto, Eri, Cahill, Katherine N., Bhattacharyya, Neil, Katz, Howard R., Berger, Bonnie, Laidlaw, Tanya M., Boyce, Joshua A., Barrett, Nora A., Shalek, Alex K.
Publicado 2018

Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas

por Amoozgar, Zohreh, Kloepper, Jonas, Ren, Jun, Tay, Rong En, Kazer, Samuel W., Kiner, Evgeny, Krishnan, Shanmugarajan, Posada, Jessica M., Ghosh, Mitrajit, Mamessier, Emilie, Wong, Christina, Ferraro, Gino B., Batista, Ana, Wang, Nancy, Badeaux, Mark, Roberge, Sylvie, Xu, Lei, Huang, Peigen, Shalek, Alex K., Fukumura, Dai, Kim, Hye-Jung, Jain, Rakesh K.
Publicado 2021

Antiviral CD8(+) T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion

por Ranasinghe, Srinika, Lamothe, Pedro A., Soghoian, Damien Z., Kazer, Samuel W., Cole, Michael B., Shalek, Alex K., Yosef, Nir, Jones, R. Brad, Donaghey, Faith, Nwonu, Chioma, Jani, Priya, Clayton, Gina M., Crawford, Frances, White, Janice, Montoya, Alana, Power, Karen, Allen, Todd M., Streeck, Hendrik, Kaufmann, Daniel E., Picker, Louis J., Kappler, John W., Walker, Bruce D.
Publicado 2016

Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection

por Kazer, Samuel W., Aicher, Toby P., Muema, Daniel M., Carroll, Shaina L., Ordovas-Montanes, Jose, Miao, Vincent N., Tu, Ang A., Ziegler, Carly G. K., Nyquist, Sarah K., Wong, Emily B., Ismail, Nasreen, Dong, Mary, Moodley, Amber, Berger, Bonnie, Love, J. Christopher, Dong, Krista L., Leslie, Alasdair, Ndhlovu, Zaza M., Ndung’u, Thumbi, Walker, Bruce D., Shalek, Alex K.
Publicado 2020

HIV specific CD8(+) T(RM)-like cells in tonsils express exhaustive signatures in the absence of natural HIV control

por Fardoos, Rabiah, Nyquist, Sarah K., Asowata, Osaretin E., Kazer, Samuel W., Singh, Alveera, Ngoepe, Abigail, Giandhari, Jennifer, Mthabela, Ntombifuthi, Ramjit, Dirhona, Singh, Samita, Karim, Farina, Buus, Søren, Anderson, Frank, Porterfield, J. Zachary, Sibiya, Andile L., Bipath, Rishan, Moodley, Kumeshan, Kuhn, Warren, Berger, Bonnie, Nguyen, Son, de Oliveira, Tulio, Ndung’u, Thumbi, Goulder, Philip, Shalek, Alex K., Leslie, Alasdair, Kløverpris, Henrik N.
Publicado 2022

Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

por Ardain, Amanda, Domingo-Gonzalez, Racquel, Das, Shibali, Kazer, Samuel W., Howard, Nicole C., Singh, Alveera, Ahmed, Mushtaq, Nhamoyebonde, Shepherd, Rangel-Moreno, Javier, Ogongo, Paul, Lu, Lan, Ramsuran, Duran, de la Luz Garcia-Hernandez, Maria, Ulland, Tyler, Darby, Matthew, Park, Eugene, Karim, Farina, Melocchi, Laura, Madansein, Rajhmun, Dullabh, Kaylesh Jay, Dunlap, Micah, Marin-Agudelo, Nancy, Ebihara, Takashi, Ndung’u, Thumbi, Kaushal, Deepak, Pym, Alexander S., Kolls, Jay K., Steyn, Adrie, Zúñiga, Joaquín, Horsnell, William, Yokoyama, Wayne, Shalek, Alex K., Kløverpris, Henrik N., Colonna, Marco, Leslie, Alasdair, Khader, Shabaana A.
Publicado 2019

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

por Ziegler, Carly G.K., Allon, Samuel J., Nyquist, Sarah K., Mbano, Ian M., Miao, Vincent N., Tzouanas, Constantine N., Cao, Yuming, Yousif, Ashraf S., Bals, Julia, Hauser, Blake M., Feldman, Jared, Muus, Christoph, Wadsworth, Marc H., Kazer, Samuel W., Hughes, Travis K., Doran, Benjamin, Gatter, G. James, Vukovic, Marko, Taliaferro, Faith, Mead, Benjamin E., Guo, Zhiru, Wang, Jennifer P., Gras, Delphine, Plaisant, Magali, Ansari, Meshal, Angelidis, Ilias, Adler, Heiko, Sucre, Jennifer M.S., Taylor, Chase J., Lin, Brian, Waghray, Avinash, Mitsialis, Vanessa, Dwyer, Daniel F., Buchheit, Kathleen M., Boyce, Joshua A., Barrett, Nora A., Laidlaw, Tanya M., Carroll, Shaina L., Colonna, Lucrezia, Tkachev, Victor, Peterson, Christopher W., Yu, Alison, Zheng, Hengqi Betty, Gideon, Hannah P., Winchell, Caylin G., Lin, Philana Ling, Bingle, Colin D., Snapper, Scott B., Kropski, Jonathan A., Theis, Fabian J., Schiller, Herbert B., Zaragosi, Laure-Emmanuelle, Barbry, Pascal, Leslie, Alasdair, Kiem, Hans-Peter, Flynn, JoAnne L., Fortune, Sarah M., Berger, Bonnie, Finberg, Robert W., Kean, Leslie S., Garber, Manuel, Schmidt, Aaron G., Lingwood, Daniel, Shalek, Alex K., Ordovas-Montanes, Jose
Publicado 2020