tRNA-Derived Fragments (tRFs): Emerging New Roles for an Ancient RNA in the Regulation of Gene Expression

por Keam, Simon P., Hutvagner, Gyorgy
Publicado 2015

The long and the short of it: the MDM4 tail so far

por Haupt, Sue, Mejía-Hernández, Javier Octavio, Vijayakumaran, Reshma, Keam, Simon P, Haupt, Ygal
Publicado 2019

Corrigendum to ‘The long and the short of it: the MDM4 tail so far’

por Haupt, Sue, Mejía-Hernández, Javier Octavio, Vijayakumaran, Reshma, Keam, Simon P, Haupt, Ygal
Publicado 2019

TP53 Status, Patient Sex, and the Immune Response as Determinants of Lung Cancer Patient Survival

por Freudenstein, Donald, Litchfield, Cassandra, Caramia, Franco, Wright, Gavin, Solomon, Benjamin J., Ball, David, Keam, Simon P., Neeson, Paul, Haupt, Ygal, Haupt, Sue
Publicado 2020

Primary and metastatic breast tumors cross-talk to influence immunotherapy responses

por Oliver, Amanda J, Keam, Simon P, von Scheidt, Bianca, Zanker, Damien J, Harrison, Aaron J, Tantalo, Daniela GM, Darcy, Phillip K, Kershaw, Michael H, Slaney, Clare Y
Publicado 2020

Immune molecular profiling of a multiresistant primary prostate cancer with a neuroendocrine-like phenotype: a case report

por Williams, Scott G., Aw Yeang, Han Xian, Mitchell, Catherine, Caramia, Franco, Byrne, David J., Fox, Stephen B., Haupt, Sue, Schittenhelm, Ralf B., Neeson, Paul J., Haupt, Ygal, Keam, Simon P.
Publicado 2020

The human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells

por Keam, Simon P., Young, Paul E., McCorkindale, Alexandra L., Dang, Thurston H.Y., Clancy, Jennifer L., Humphreys, David T., Preiss, Thomas, Hutvagner, Gyorgy, Martin, David I.K., Cropley, Jennifer E., Suter, Catherine M.
Publicado 2014

Tissue‐specific tumor microenvironments influence responses to immunotherapies

por Oliver, Amanda J, Davey, Ashleigh S, Keam, Simon P, Mardiana, Sherly, Chan, Jack D, von Scheidt, Bianca, Beavis, Paul A, House, Imran G, Van Audernaerde, Jonas RM, Darcy, Phillip K, Kershaw, Michael H, Slaney, Clare Y
Publicado 2019

High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot

por Keam, Simon P, Halse, Heloise, Nguyen, Thu, Wang, Minyu, Van Kooten Losio, Nicolas, Mitchell, Catherine, Caramia, Franco, Byrne, David J, Haupt, Sue, Ryland, Georgina, Darcy, Phillip K, Sandhu, Shahneen, Blombery, Piers, Haupt, Ygal, Williams, Scott G, Neeson, Paul J
Publicado 2020

Tissue-resident memory T cells from a metastatic vaginal melanoma patient are tumor-responsive T cells and increase after anti-PD-1 treatment

por Pizzolla, Angela, Keam, Simon Paul, Vergara, Ismael A, Caramia, Franco, Thio, Niko, Wang, Minyu, Kocovski, Nikolce, Tantalo, Daniela, Jabbari, Jafar, Au-Yeung, George, Sandhu, Shahneen, Gyorki, David E, Weppler, Alison, Perdicchio, Maurizio, McArthur, Grant A, Papenfuss, Anthony T, Neeson, Paul Joseph
Publicado 2022

Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity

por Cropley, Jennifer E., Eaton, Sally A., Aiken, Alastair, Young, Paul E., Giannoulatou, Eleni, Ho, Joshua W.K., Buckland, Michael E., Keam, Simon P., Hutvagner, Gyorgy, Humphreys, David T., Langley, Katherine G., Henstridge, Darren C., Martin, David I.K., Febbraio, Mark A., Suter, Catherine M.
Publicado 2016

Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss

por Mejía-Hernández, Javier Octavio, Keam, Simon P., Saleh, Reem, Muntz, Fenella, Fox, Stephen B., Byrne, David, Kogan, Arielle, Pang, Lokman, Huynh, Jennifer, Litchfield, Cassandra, Caramia, Franco, Lozano, Guillermina, He, Hua, You, James M., Sandhu, Shahneen, Williams, Scott G., Haupt, Ygal, Haupt, Sue
Publicado 2022

Myeloma natural killer cells are exhausted and have impaired regulation of activation

por D’Souza, Criselle, Keam, Simon P., Yeang, Han Xian Aw, Neeson, Michael, Richardson, Kelden, Hsu, Andy K., Canfield, Rachael, Bezman, Natalie, Robbins, Michael, Quach, Hang, Ritchie, David S., Harrison, Simon J., Trapani, Joseph A., Prince, H. Miles, Beavis, Paul A., Darcy, Phillip K., Neeson, Paul J.
Publicado 2021

Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments

por Feng, Yuzhou, Yang, Tianpei, Zhu, John, Li, Mabel, Doyle, Maria, Ozcoban, Volkan, Bass, Greg T., Pizzolla, Angela, Cain, Lachlan, Weng, Sirui, Pasam, Anupama, Kocovski, Nikolce, Huang, Yu-Kuan, Keam, Simon P., Speed, Terence P., Neeson, Paul J., Pearson, Richard B., Sandhu, Shahneen, Goode, David L., Trigos, Anna S.
Publicado 2023

The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells

por Richardson, Kelden, Keam, Simon P., Zhu, Joe Jiang, Meyran, Deborah, D’Souza, Criselle, Macdonald, Sean, Campbell, Kerry, Robbins, Michael, Bezman, Natalie A., Todd, Kirsten, Quach, Hang, Ritchie, David S., Harrison, Simon J., Prince, H. Miles, Trapani, Joseph A., Jenkins, Misty R., Beavis, Paul A., Darcy, Phillip K., Neeson, Paul J.
Publicado 2022

Tumor immune microenvironment of primary prostate cancer with and without germline mutations in homologous recombination repair genes

por Trigos, Anna Sofia, Pasam, Anupama, Banks, Patricia, Wallace, Roslyn, Guo, Christina, Keam, Simon, Thorne, Heather, Mitchell, Catherine, Lade, Stephen, Clouston, David, Hakansson, Alexander, Liu, Yang, Blyth, Benjamin, Murphy, Declan, Lawrentschuk, Nathan, Bolton, Damien, Moon, Daniel, Darcy, Phil, Haupt, Ygal, Williams, Scott G, Castro, Elena, Olmos, David, Goode, David, Neeson, Paul, Sandhu, Shahneen
Publicado 2022

E6AP Promotes a Metastatic Phenotype in Prostate Cancer

por Gamell, Cristina, Bandilovska, Ivona, Gulati, Twishi, Kogan, Arielle, Lim, Syer Choon, Kovacevic, Zaklina, Takano, Elena A., Timpone, Clelia, Agupitan, Arjelle D., Litchfield, Cassandra, Blandino, Giovanni, Horvath, Lisa G., Fox, Stephen B., Williams, Scott G., Russo, Andrea, Gallo, Enzo, Paul, Piotr J., Mitchell, Catherine, Sandhu, Shahneen, Keam, Simon P., Haupt, Sue, Richardson, Des R., Haupt, Ygal
Publicado 2019

Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression

por Mangiola, Stefano, McCoy, Patrick, Modrak, Martin, Souza-Fonseca-Guimaraes, Fernando, Blashki, Daniel, Stuchbery, Ryan, Keam, Simon P., Kerger, Michael, Chow, Ken, Nasa, Chayanica, Le Page, Melanie, Lister, Natalie, Monard, Simon, Peters, Justin, Dundee, Phil, Williams, Scott G., Costello, Anthony J., Neeson, Paul J., Pal, Bhupinder, Huntington, Nicholas D., Corcoran, Niall M., Papenfuss, Anthony T., Hovens, Christopher M.
Publicado 2021

Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status

por Mejía-Hernández, Javier Octavio, Raghu, Dinesh, Caramia, Franco, Clemons, Nicholas, Fujihara, Kenji, Riseborough, Thomas, Teunisse, Amina, Jochemsen, Aart G., Abrahmsén, Lars, Blandino, Giovanni, Russo, Andrea, Gamell, Cristina, Fox, Stephen B., Mitchell, Catherine, Takano, Elena A., Byrne, David, Miranda, Panimaya Jeffreena, Saleh, Reem, Thorne, Heather, Sandhu, Shahneen, Williams, Scott G., Keam, Simon P., Haupt, Ygal, Haupt, Sue
Publicado 2022

MAIT cells regulate NK cell-mediated tumor immunity

por Petley, Emma V., Koay, Hui-Fern, Henderson, Melissa A., Sek, Kevin, Todd, Kirsten L., Keam, Simon P., Lai, Junyun, House, Imran G., Li, Jasmine, Zethoven, Magnus, Chen, Amanda X. Y., Oliver, Amanda J., Michie, Jessica, Freeman, Andrew J., Giuffrida, Lauren, Chan, Jack D., Pizzolla, Angela, Mak, Jeffrey Y. W., McCulloch, Timothy R., Souza-Fonseca-Guimaraes, Fernando, Kearney, Conor J., Millen, Rosemary, Ramsay, Robert G., Huntington, Nicholas D., McCluskey, James, Oliaro, Jane, Fairlie, David P., Neeson, Paul J., Godfrey, Dale I., Beavis, Paul A., Darcy, Phillip K.
Publicado 2021