Phenylpyrrole fungicides act on triosephosphate isomerase to induce methylglyoxal stress and alter hybrid histidine kinase activity

por Brandhorst, T. Tristan, Kean, Iain R. L., Lawry, Stephanie M., Wiesner, Darin L., Klein, Bruce S.
Publicado 2019

Full genomic characterization of a porcine rotavirus strain detected in an asymptomatic piglet in Accra, Ghana

por Stubbs, Samuel C. B., Quaye, Osbourne, Acquah, Maame Ekua, Adadey, Samuel Mawuli, Kean, Iain R. L., Gupta, Srishti, Blacklaws, Barbara A.
Publicado 2020

P48 The limited yield of cultures in the critically ill child

por Clark, John, White, Deborah, Daubney, Esther, Curran, Martin, Bousfield, Rachel, Gouliouris, Theodore, Powell, Elizabeth, Palmer, Adam, Agrawal, Shruti, Inwald, David, Kean, Iain, Török, M. Estée, Baker, Stephen, Pathan, Nazima
Publicado 2022

Low diagnostic yield and time to diagnostic confirmation results in prolonged use of antimicrobials in critically ill children

por Clark, John, White, Deborah, Daubney, Esther, Curran, Martin, Bousfield, Rachel, Gouliouris, Theodore, Powell, Elizabeth, Palmer, Adam, Agrawal, Shruti, Inwald, David, Kean, Iain, Török, M. Estée, Baker, Stephen, Pathan, Nazima
Publicado 2022

Biosynthesis of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis

por McHugh, Rebecca E., Munnoch, John T., Braes, Robyn E., McKean, Iain J. W., Giard, Josephine, Taladriz-Sender, Andrea, Peschke, Frederik, Burley, Glenn A., Roe, Andrew J., Hoskisson, Paul A.
Publicado 2022

A blueprint for the implementation of a validated approach for the detection of SARS-Cov2 in clinical samples in academic facilities

por Sridhar, Sushmita, Forrest, Sally, Kean, Iain, Young, Jamie, Bartholdson Scott, Josefin, Maes, Mailis, Pereira-Dias, Joana, Parmar, Surendra, Routledge, Matthew, Sparkes, Dominic, Rivett, Lucy, Dougan, Gordon, Weekes, Michael, Curran, Martin, Goodfellow, Ian, Baker, Stephen
Publicado 2020

The effects of antibiotic use on the dynamics of the microbiome and resistome in pigs

por Tams, Katrine Wegener, Larsen, Inge, Hansen, Julie Elvekjær, Spiegelhauer, Henrik, Strøm-Hansen, Alexander Damm, Rasmussen, Sophia, Ingham, Anna Cäcilia, Kalmar, Lajos, Kean, Iain Robert Louis, Angen, Øystein, Holmes, Mark A., Pedersen, Karl, Jelsbak, Lars, Folkesson, Anders, Larsen, Anders Rhod, Strube, Mikael Lenz
Publicado 2023

Rapid Assay for Sick Children with Acute Lung infection Study (RASCALS): diagnostic cohort study protocol

por Clark, John Alexander, Kean, Iain Robert Louis, Curran, Martin D, Khokhar, Fahad, White, Deborah, Daubney, Esther, Conway Morris, Andrew, Navapurkar, Vilas, Bartholdson Scott, Josefin, Maes, Mailis, Bousfield, Rachel, Gouliouris, Theodore, Agrawal, Shruti, Inwald, David, Zhang, Zhenguang, Török, M Estée, Baker, Stephen, Pathan, Nazima
Publicado 2021

Profiling gut microbiota and bile acid metabolism in critically ill children

por Kean, Iain Robert Louis, Wagner, Joseph, Wijeyesekera, Anisha, De Goffau, Marcus, Thurston, Sarah, Clark, John A., White, Deborah K., Ridout, Jenna, Agrawal, Shruti, Kayani, Riaz, O’Donnell, Roddy, Ramnarayan, Padmanabhan, Peters, Mark J., Klein, Nigel, Holmes, Elaine, Parkhill, Julian, Baker, Stephen, Pathan, Nazima
Publicado 2022

The rapid detection of respiratory pathogens in critically ill children

por Clark, John A., Conway Morris, Andrew, Curran, Martin D., White, Deborah, Daubney, Esther, Kean, Iain R. L., Navapurkar, Vilas, Bartholdson Scott, Josefin, Maes, Mailis, Bousfield, Rachel, Török, M. Estée, Inwald, David, Zhang, Zhenguang, Agrawal, Shruti, Kanaris, Constantinos, Khokhar, Fahad, Gouliouris, Theodore, Baker, Stephen, Pathan, Nazima
Publicado 2023

HAM-ART: An optimised culture-free Hi-C metagenomics pipeline for tracking antimicrobial resistance genes in complex microbial communities

por Kalmar, Lajos, Gupta, Srishti, Kean, Iain R. L., Ba, Xiaoliang, Hadjirin, Nazreen, Lay, Elizabeth M., de Vries, Stefan P. W., Bateman, Michael, Bartlet, Harriet, Hernandez-Garcia, Juan, Tucker, Alexander W., Restif, Olivier, Stevens, Mark P., Wood, James L. N., Maskell, Duncan J., Grant, Andrew J., Holmes, Mark A.
Publicado 2022