A minute fraction of α-synuclein in extracellular vesicles may be a major contributor to α-synuclein spreading following autophagy inhibition

por Taha, Hash Brown, Kearney, Brian, Bitan, Gal
Publicado 2022

Larval Tolerance to Salinity in Three Species of Australian Anuran: An Indication of Saline Specialisation in Litoria aurea

por Kearney, Brian D., Byrne, Phillip G., Reina, Richard D.
Publicado 2012

Short- and long-term consequences of developmental saline stress: impacts on anuran respiration and behaviour

por Kearney, Brian D., Byrne, Phillip G., Reina, Richard D.
Publicado 2016

Lack of Clinically Relevant Effect of Bictegravir (BIC, B) on Metformin (MET) Pharmacokinetics (PK) and Pharmacodynamics (PD)

por Custodio, Joseph, West, Steve, Yu, Amanda, Martin, Hal, Graham, Hiba, Quirk, Erin, Kearney, Brian
Publicado 2017

Pharmacokinetics, Pharmacodynamics, and Safety of Entospletinib, a Novel pSYK Inhibitor, Following Single and Multiple Oral Dosing in Healthy Volunteers

por Ramanathan, Srini, Di Paolo, Julie A., Jin, Feng, Shao, Lixin, Sharma, Shringi, Robeson, Michelle, Kearney, Brian P.
Publicado 2016

A comprehensive evaluation in clinic and physiologically‐based pharmacokinetic modeling and simulation to confirm lack of cytochrome P450–mediated drug–drug interaction potential f...

por Yang, Ziping, Rioux, Nathalie, Vincent, Ludwig, Jones, Hannah M., Cha, David, Plummer, Andrew, Wilfret, David, Kearney, Brian P.
Publicado 2023

A Multi-Compartment, Single and Multiple Dose Pharmacokinetic Study of the Vaginal Candidate Microbicide 1% Tenofovir Gel

por Schwartz, Jill L., Rountree, Wes, Kashuba, Angela D. M., Brache, Vivian, Creinin, Mitchell D., Poindexter, Alfred, Kearney, Brian P.
Publicado 2011

Lack of clinically important PK interaction between coformulated ledipasvir/sofosbuvir and rilpivirine/emtricitabine/tenofovir alafenamide

por Custodio, Joseph M., Chuck, Susan K., Chu, Hoa, Cao, Huyen, Ma, Grace, Flaherty, John, Ling, John, Kearney, Brian P.
Publicado 2017

Modeling the stability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on skin, currency, and clothing

por Harbourt, David E., Haddow, Andrew D., Piper, Ashley E., Bloomfield, Holly, Kearney, Brian J., Fetterer, David, Gibson, Kathleen, Minogue, Timothy
Publicado 2020

Cytochrome P450 3A Induction Predicts P‐glycoprotein Induction; Part 1: Establishing Induction Relationships Using Ascending Dose Rifampin

por Lutz, Justin D., Kirby, Brian J., Wang, Lu, Song, Qinghua, Ling, John, Massetto, Benedetta, Worth, Angela, Kearney, Brian P., Mathias, Anita
Publicado 2018

Cytochrome P450 3A Induction Predicts P‐glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine

por Lutz, Justin D., Kirby, Brian J., Wang, Lu, Song, Qinghua, Ling, John, Massetto, Benedetta, Worth, Angela, Kearney, Brian P., Mathias, Anita
Publicado 2018

Exposure‐response relationships for the efficacy and safety of filgotinib and its metabolite GS‐829845 in subjects with rheumatoid arthritis based on phase 2 and phase 3 studies...

por Meng, Amy, Anderson, Kacey, Nelson, Cara, Ni, Liyun, Chuang, Shu‐Min, Bellanti, Francesco, Chang, Peter, Comisar, Craig, Kearney, Brian P., Bartok, Beatrix, Mathias, Anita
Publicado 2022

Evaluation of ViroCyt(®) Virus Counter for Rapid Filovirus Quantitation

por Rossi, Cynthia A., Kearney, Brian J., Olschner, Scott P., Williams, Priscilla L., Robinson, Camenzind G., Heinrich, Megan L., Zovanyi, Ashley M., Ingram, Michael F., Norwood, David A., Schoepp, Randal J.
Publicado 2015

Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 in Aerosol Suspensions

por Fears, Alyssa C., Klimstra, William B., Duprex, Paul, Hartman, Amy, Weaver, Scott C., Plante, Kenneth S., Mirchandani, Divya, Plante, Jessica Ann, Aguilar, Patricia V., Fernández, Diana, Nalca, Aysegul, Totura, Aysegul, Dyer, David, Kearney, Brian, Lackemeyer, Matthew, Bohannon, J. Kyle, Johnson, Reed, Garry, Robert F., Reed, Doug S., Roy, Chad J.
Publicado 2020

Early indicators of exposure to biological threat agents using host gene profiles in peripheral blood mononuclear cells

por Das, Rina, Hammamieh, Rasha, Neill, Roger, Ludwig, George V, Eker, Steven, Lincoln, Patrick, Ramamoorthy, Preveen, Dhokalia, Apsara, Mani, Sachin, Mendis, Chanaka, Cummings, Christiano, Kearney, Brian, Royaee, Atabak, Huang, Xiao-Zhe, Paranavitana, Chrysanthi, Smith, Leonard, Peel, Sheila, Kanesa-Thasan, Niranjan, Hoover, David, Lindler, Luther E, Yang, David, Henchal, Erik, Jett, Marti
Publicado 2008

Exposure Route Influences Disease Severity in the COVID-19 Cynomolgus Macaque Model

por Bixler, Sandra L., Stefan, Christopher P., Jay, Alexandra N., Rossi, Franco D., Ricks, Keersten M., Shoemaker, Charles J., Moreau, Alicia M., Zeng, Xiankun, Hooper, Jay W., Dyer, David N., Frick, Ondraya M., Koehler, Jeffrey W., Kearney, Brian J., DiPinto, Nina, Liu, Jun, Tostenson, Samantha D., Clements, Tamara L., Smith, Jeffrey M., Johnson, Joshua A., Berrier, Kerry L., Esham, Heather L., Delp, Korey L., Coyne, Susan R., Bloomfield, Holly A., Kuehnert, Paul A., Akers, Kristen, Gibson, Kathleen M., Minogue, Timothy D., Nalca, Aysegul, Pitt, Margaret L. M.
Publicado 2022

Reduced evolutionary rate in reemerged Ebola virus transmission chains

por Blackley, David J., Wiley, Michael R., Ladner, Jason T., Fallah, Mosoka, Lo, Terrence, Gilbert, Merle L., Gregory, Christopher, D’ambrozio, Jonathan, Coulter, Stewart, Mate, Suzanne, Balogun, Zephaniah, Kugelman, Jeffrey, Nwachukwu, William, Prieto, Karla, Yeiah, Adolphus, Amegashie, Fred, Kearney, Brian, Wisniewski, Meagan, Saindon, John, Schroth, Gary, Fakoli, Lawrence, Diclaro, Joseph W., Kuhn, Jens H., Hensley, Lisa E., Jahrling, Peter B., Ströher, Ute, Nichol, Stuart T., Massaquoi, Moses, Kateh, Francis, Clement, Peter, Gasasira, Alex, Bolay, Fatorma, Monroe, Stephan S., Rambaut, Andrew, Sanchez-Lockhart, Mariano, Scott Laney, A., Nyenswah, Tolbert, Christie, Athalia, Palacios, Gustavo
Publicado 2016

Development of a coronavirus disease 2019 nonhuman primate model using airborne exposure

por Johnston, Sara C., Ricks, Keersten M., Jay, Alexandra, Raymond, Jo Lynne, Rossi, Franco, Zeng, Xiankun, Scruggs, Jennifer, Dyer, David, Frick, Ondraya, Koehler, Jeffrey W., Kuehnert, Paul A., Clements, Tamara L., Shoemaker, Charles J., Coyne, Susan R., Delp, Korey L., Moore, Joshua, Berrier, Kerry, Esham, Heather, Shamblin, Joshua, Sifford, Willie, Fiallos, Jimmy, Klosterman, Leslie, Stevens, Stephen, White, Lauren, Bowling, Philip, Garcia, Terrence, Jensen, Christopher, Ghering, Jeanean, Nyakiti, David, Bellanca, Stephanie, Kearney, Brian, Giles, Wendy, Alli, Nazira, Paz, Fabian, Akers, Kristen, Danner, Denise, Barth, James, Johnson, Joshua A., Durant, Matthew, Kim, Ruth, Hooper, Jay W., Smith, Jeffrey M., Kugelman, Jeffrey R., Beitzel, Brett F., Gibson, Kathleen M., Pitt, Margaret L. M., Minogue, Timothy D., Nalca, Aysegul
Publicado 2021