Proton Pump Inhibitors in Pediatrics: Mechanism of Action, Pharmacokinetics, Pharmacogenetics, and Pharmacodynamics

por Ward, Robert M., Kearns, Gregory L.
Publicado 2013

How to Conduct Clinical Trials in Children: A Tutorial

por Shakhnovich, Valentina, Hornik, Christoph P., Kearns, Gregory L., Weigel, Jaylene, Abdel‐Rahman, Susan M.
Publicado 2019

Systemic exposure to menthol following administration of peppermint oil to paediatric patients

por Kearns, Gregory L, Chumpitazi, Bruno Pedro, Abdel-Rahman, Susan M, Garg, Uttam, Shulman, Robert J
Publicado 2015

Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity

por James, Laura, Yan, Ke, Pence, Lisa, Simpson, Pippa, Bhattacharyya, Sudeepa, Gill, Pritmohinder, Letzig, Lynda, Kearns, Gregory, Beger, Richard
Publicado 2015

Decreased Pregnane X Receptor Expression in Children with Active Crohn’s Disease

por Shakhnovich, Valentina, Vyhlidal, Carrie, Friesen, Craig, Hildreth, Amber, Singh, Vivekanand, Daniel, James, Kearns, Gregory L., Leeder, J. Steven
Publicado 2016

Montelukast in the treatment of duodenal eosinophilia in children with dyspepsia: Effect on eosinophil density and activation in relation to pharmacokinetics

por Friesen, Craig A, Neilan, Nancy A, Schurman, Jennifer V, Taylor, Debra L, Kearns, Gregory L, Abdel-Rahman, Susan M
Publicado 2009

Granzyme B and miR-378a Interaction in Acetaminophen Toxicity in Children

por McCullough, Sandra, Dweep, Harsh, McGill, Mitchell R., Bhattacharyya, Sudeepa, James, Laura, Frankowski, Sara, Woodall, Aaron, Kearns, Gregory, Gill, Pritmohinder
Publicado 2020

Targeted metabolomic profiling indicates structure-based perturbations in serum phospholipids in children with acetaminophen overdose

por Bhattacharyya, Sudeepa, Pence, Lisa, Yan, Ke, Gill, Pritmohinder, Luo, Chunqiao, Letzig, Lynda G., Simpson, Pippa M., Kearns, Gregory L., Beger, Richard D., James, Laura P.
Publicado 2016

Utility of the (13)C‐pantoprazole breath test as a CYP2C19 phenotyping probe for children

por Feldman, Keith, Kearns, Gregory L., Pearce, Robin E., Abdel‐Rahman, Susan M., Steven Leeder, James, Friesen, Alec, Staggs, Vincent S., Gaedigk, Andrea, Weigel, Jaylene, Shakhnovich, Valentina
Publicado 2022

Peppermint oil effects on the gut microbiome in children with functional abdominal pain

por Thapa, Santosh, Luna, Ruth Ann, Chumpitazi, Bruno P., Oezguen, Numan, Abdel‐Rahman, Susan M., Garg, Uttam, Musaad, Salma, Versalovic, James, Kearns, Gregory L., Shulman, Robert J.
Publicado 2022

Population Pharmacokinetics and Exploratory Exposure‐Response Relationships of Diazepam in Children Treated for Status Epilepticus

por Ku, Lawrence C., Hornik, Christoph P., Beechinor, Ryan J., Chamberlain, James M., Guptill, Jeffrey T., Harper, Barrie, Capparelli, Edmund V., Martz, Karen, Anand, Ravinder, Cohen‐Wolkowiez, Michael, Gonzalez, Daniel, Furda, Gary, Benjamin, Danny, Kearns, Gregory L., Paul, Ian M., Sullivan, Jan, Hornik, Christoph P., Wade, Kelly, Siegel, David, Taylor‐Zapata, Perdita, Zajicek, Anne, Ren, Zhaoxia, Tsilou, Ekaterini, Pagan, Alice, Simone, Gina, Ku, Lawrence, Mills, Mary, Watt, Kevin
Publicado 2018

Recommendations to Enhance Pediatric Cardiovascular Drug Development: Report of a Multi‐Stakeholder Think Tank

por Torok, Rachel D., Li, Jennifer S., Kannankeril, Prince J., Atz, Andrew M., Bishai, Raafat, Bolotin, Ellen, Breitenstein, Stefanie, Chen, Cathy, Diacovo, Thomas, Feltes, Timothy, Furlong, Patricia, Hanna, Michael, Graham, Eric M., Hsu, Daphne, Ivy, D. Dunbar, Murphy, Dianne, Kammerman, Lisa A., Kearns, Gregory, Lawrence, John, Lebeaut, Brigitte, Li, Danshi, Male, Christoph, McCrindle, Brian, Mugnier, Pierre, Newburger, Jane W., Pearson, Gail D., Peiris, Vasum, Percival, Lisa, Pina, Miriam, Portman, Ronald, Shaddy, Robert, Stockbridge, Norman L., Temple, Robert, Hill, Kevin D.
Publicado 2018