A rational route to probing membrane proteins

por Keating, Amy E
Publicado 2007

AVID: An integrative framework for discovering functional relationships among proteins

por Jiang, Taijiao, Keating, Amy E
Publicado 2005

A Set of Computationally Designed Orthogonal Antiparallel Homodimers that Expands the Synthetic Coiled-Coil Toolkit

por Negron, Christopher, Keating, Amy E.
Publicado 2014

Design of protein-interaction specificity affords selective bZIP-binding peptides

por Grigoryan, Gevorg, Reinke, Aaron W., Keating, Amy E.
Publicado 2009

Predicting specificity in bZIP coiled-coil protein interactions

por Fong, Jessica H, Keating, Amy E, Singh, Mona
Publicado 2004

Genome-Wide Prediction and Validation of Peptides That Bind Human Prosurvival Bcl-2 Proteins

por DeBartolo, Joe, Taipale, Mikko, Keating, Amy E.
Publicado 2014

Data-Driven Prediction and Design of bZIP Coiled-Coil Interactions

por Potapov, Vladimir, Kaplan, Jenifer B., Keating, Amy E.
Publicado 2015

Multicoil2: Predicting Coiled Coils and Their Oligomerization States from Sequence in the Twilight Zone

por Trigg, Jason, Gutwin, Karl, Keating, Amy E., Berger, Bonnie
Publicado 2011

Tertiary motifs as building blocks for the design of protein‐binding peptides

por Swanson, Sebastian, Sivaraman, Venkatesh, Grigoryan, Gevorg, Keating, Amy E.
Publicado 2022

The MCL-1 BH3 Helix is an Exclusive MCL-1 inhibitor and Apoptosis Sensitizer

por Stewart, Michelle L., Fire, Emiko, Keating, Amy E., Walensky, Loren D.
Publicado 2010

Modular assembly of a protein nanotriangle using orthogonally interacting coiled coils

por Park, Won Min, Bedewy, Mostafa, Berggren, Karl K., Keating, Amy E.
Publicado 2017

SYNZIP Protein Interaction Toolbox: in Vitro and in Vivo Specifications of Heterospecific Coiled-Coil Interaction Domains

por Thompson, Kenneth Evan, Bashor, Caleb J., Lim, Wendell A., Keating, Amy E.
Publicado 2012

Marginal specificity in protein interactions constrains evolution of a paralogous family

por Ghose, Dia A., Przydzial, Kaitlyn E., Mahoney, Emily M., Keating, Amy E., Laub, Michael T.
Publicado 2023

Ultra-Fast Evaluation of Protein Energies Directly from Sequence

por Grigoryan, Gevorg, Zhou, Fei, Lustig, Steve R, Ceder, Gerbrand, Morgan, Dane, Keating, Amy E
Publicado 2006

Designed BH3 Peptides with High Affinity and Specificity for Targeting Mcl-1 in Cells

por Foight, Glenna Wink, Ryan, Jeremy A., Gullá, Stefano V., Letai, Anthony, Keating, Amy E.
Publicado 2014

Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1

por Jenson, Justin M, Ryan, Jeremy A, Grant, Robert A, Letai, Anthony, Keating, Amy E
Publicado 2017

Molecular determinants of TRAF6 binding specificity suggest that native interaction partners are not optimized for affinity

por Halpin, Jackson C., Whitney, Dustin, Rigoldi, Federica, Sivaraman, Venkat, Singer, Avinoam, Keating, Amy E.
Publicado 2022

Neural network‐derived Potts models for structure‐based protein design using backbone atomic coordinates and tertiary motifs

por Li, Alex J., Lu, Mindren, Desta, Israel, Sundar, Vikram, Grigoryan, Gevorg, Keating, Amy E.
Publicado 2023

Combinatorial bZIP dimers display complex DNA-binding specificity landscapes

por Rodríguez-Martínez, José A, Reinke, Aaron W, Bhimsaria, Devesh, Keating, Amy E, Ansari, Aseem Z
Publicado 2017

A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers

por Hwang, Theresa, Parker, Sara S, Hill, Samantha M, Ilunga, Meucci W, Grant, Robert A, Mouneimne, Ghassan, Keating, Amy E
Publicado 2021