Aptamers as therapeutics

por Keefe, Anthony D., Pai, Supriya, Ellington, Andrew
Publicado 2010

Universal strategies for the DNA-encoding of libraries of small molecules using the chemical ligation of oligonucleotide tags

por Litovchick, Alexander, Clark, Matthew A, Keefe, Anthony D
Publicado 2014

Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry

por Litovchick, Alexander, Tian, Xia, Monteiro, Michael I., Kennedy, Kaitlyn M., Guié, Marie-Aude, Centrella, Paolo, Zhang, Ying, Clark, Matthew A., Keefe, Anthony D.
Publicado 2019

Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library

por Litovchick, Alexander, Dumelin, Christoph E., Habeshian, Sevan, Gikunju, Diana, Guié, Marie-Aude, Centrella, Paolo, Zhang, Ying, Sigel, Eric A., Cuozzo, John W., Keefe, Anthony D., Clark, Matthew A.
Publicado 2015

Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action

por Fernández-Montalván, Amaury E., Berger, Markus, Kuropka, Benno, Koo, Seong Joo, Badock, Volker, Weiske, Joerg, Puetter, Vera, Holton, Simon J., Stöckigt, Detlef, ter Laak, Antonius, Centrella, Paolo A., Clark, Matthew A., Dumelin, Christoph E., Sigel, Eric A., Soutter, Holly H., Troast, Dawn M., Zhang, Ying, Cuozzo, John W., Keefe, Anthony D., Roche, Didier, Rodeschini, Vincent, Chaikuad, Apirat, Díaz-Sáez, Laura, Bennett, James M., Fedorov, Oleg, Huber, Kilian V. M., Hübner, Jan, Weinmann, Hilmar, Hartung, Ingo V., Gorjánácz, Mátyás
Publicado 2017

Discovery of Nanomolar DCAF1 Small Molecule Ligands

por Li, Alice Shi Ming, Kimani, Serah, Wilson, Brian, Noureldin, Mahmoud, González-Álvarez, Héctor, Mamai, Ahmed, Hoffer, Laurent, Guilinger, John P., Zhang, Ying, von Rechenberg, Moritz, Disch, Jeremy S., Mulhern, Christopher J., Slakman, Belinda L., Cuozzo, John W., Dong, Aiping, Poda, Gennady, Mohammed, Mohammed, Saraon, Punit, Mittal, Manish, Modh, Pratik, Rathod, Vaibhavi, Patel, Bhashant, Ackloo, Suzanne, Santhakumar, Vijayaratnam, Szewczyk, Magdalena M, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Marcellus, Richard, Guié, Marie-Aude, Keefe, Anthony D., Brown, Peter J., Halabelian, Levon, Al-awar, Rima, Vedadi, Masoud
Publicado 2023