Fifty Years of Diazeniumdiolate Research. From Laboratory Curiosity to Broad-Spectrum Biomedical Advances

por Keefer, Larry K.
Publicado 2011

Direct Reaction of Amides with Nitric Oxide To Form Diazeniumdiolates

por Holland, Ryan J., Klose, John R., Deschamps, Jeffrey R., Cao, Zhao, Keefer, Larry K., Saavedra, Joseph E.
Publicado 2014

Aminolysis of an N-Diazeniumdiolated Amidine as an Approach to Diazeniumdiolated Ammonia

por Biswas, Debanjan, Hrabie, Joseph A., Saavedra, Joseph E., Cao, Zhao, Keefer, Larry K., Ivanic, Joseph, Holland, Ryan J.
Publicado 2014

Green tea intake is associated with urinary estrogen profiles in Japanese-American women

por Fuhrman, Barbara J, Pfeiffer, Ruth M, Wu, Anna H, Xu, Xia, Keefer, Larry K, Veenstra, Timothy D, Ziegler, Regina G
Publicado 2013

TIMP-2 mediates the anti-invasive effects of the nitric oxide-releasing prodrug JS-K in breast cancer cells

por Simeone, Ann-Marie, McMurtry, Vanity, Nieves-Alicea, René, Saavedra, Joseph E, Keefer, Larry K, Johnson, Marcella M, Tari, Ana M
Publicado 2008

Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance()

por Maciag, Anna E., Holland, Ryan J., Robert Cheng, Y.-S., Rodriguez, Luis G., Saavedra, Joseph E., Anderson, Lucy M., Keefer, Larry K.
Publicado 2013

Structure-based design of anticancer prodrug PABA/NO

por Ji, Xinhua, Pal, Ajai, Kalathur, Ravi, Hu, Xun, Gu, Yijun, Saavedra, Joseph E, Buzard, Gregory S, Srinivasan, Aloka, Keefer, Larry K, Singh, Shivendra V
Publicado 2009

Dual Mechanisms of HNO Generation by a Nitroxyl Prodrug of the Diazeniumdiolate (NONOate) Class

por Andrei, Daniela, Salmon, Debra J., Donzelli, Sonia, Wahab, Azadeh, Klose, John R., Citro, Michael L., Saavedra, Joseph E., Wink, David A., Miranda, Katrina M., Keefer, Larry K.
Publicado 2010

Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy

por Weiss, Jonathan M., Ridnour, Lisa A., Back, Tim, Hussain, S. Perwez, He, Peijun, Maciag, Anna E., Keefer, Larry K., Murphy, William J., Harris, Curtis C., Wink, David A., Wiltrout, Robert H.
Publicado 2010

Nitric Oxide (NO) Releasing Poly ADP-ribose Polymerase 1 (PARP-1) Inhibitors Targeted to Glutathione S-Transferase P1-Overexpressing Cancer Cells

por Maciag, Anna E., Holland, Ryan J., Kim, Youseung, Kumari, Vandana, Luthers, Christina E., Sehareen, Waheed S., Biswas, Debanjan, Morris, Nicole L., Ji, Xinhua, Anderson, Lucy M., Saavedra, Joseph E., Keefer, Larry K.
Publicado 2014

Hydrolytic Reactivity Trends among Potential Prodrugs of the O(2)-Glycosylated Diazeniumdiolate Family. Targeting Nitric Oxide to Macrophages for Antileishmanial Activity

por Valdez, Carlos A., Saavedra, Joseph E., Showalter, Brett M., Davies, Keith M., Wilde, Thomas C., Citro, Michael L., Barchi, Joseph J., Deschamps, Jeffrey R., Parrish, Damon, El-Gayar, Stefan, Schleicher, Ulrike, Bogdan, Christian, Keefer, Larry K.
Publicado 2008