Adenosine Deaminase Acting on RNA (ADAR) Enzymes: A Journey from Weird to Wondrous

por Keegan, Liam P., Hajji, Khadija, O’Connell, Mary A.
Publicado 2023

The Epitranscriptome and Innate Immunity

por O’Connell, Mary A., Mannion, Niamh M., Keegan, Liam P.
Publicado 2015

Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes

por Keegan, Liam P, Leroy, Anne, Sproul, Duncan, O'Connell, Mary A
Publicado 2004

New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins

por Mannion, Niamh, Arieti, Fabiana, Gallo, Angela, Keegan, Liam P., O’Connell, Mary A.
Publicado 2015

Three-Dimensional Imaging of Drosophila melanogaster

por McGurk, Leeanne, Morrison, Harris, Keegan, Liam P., Sharpe, James, O'Connell, Mary A.
Publicado 2007

Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae)

por Carpenter, Jennifer A, Keegan, Liam P, Wilfert, Lena, O'Connell, Mary A, Jiggins, Francis M
Publicado 2009

The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster

por Li, Xianghua, Overton, Ian M., Baines, Richard A., Keegan, Liam P., O’Connell, Mary A.
Publicado 2014

ADAR2 enzymes: efficient site-specific RNA editors with gene therapy aspirations

por Hajji, Khadija, Sedmík, Jiří, Cherian, Anna, Amoruso, Damiano, Keegan, Liam P., O'Connell, Mary A.
Publicado 2022

Activation of innate immunity by mitochondrial dsRNA in mouse cells lacking p53 protein

por Wiatrek, Dagmara M., Candela, Maria E., Sedmík, Jiří, Oppelt, Jan, Keegan, Liam P., O'Connell, Mary A.
Publicado 2019

Interplays of different types of epitranscriptomic mRNA modifications

por Rengaraj, Praveenkumar, Obrdlík, Aleš, Vukić, Dragana, Varadarajan, Nandan Mysore, Keegan, Liam P., Vaňáčová, Štěpánka, O’Connell, Mary A.
Publicado 2021

Editing independent effects of ADARs on the miRNA/siRNA pathways

por Heale, Bret S E, Keegan, Liam P, McGurk, Leeanne, Michlewski, Gracjan, Brindle, James, Stanton, Chloe M, Caceres, Javier F, O'Connell, Mary A
Publicado 2009

Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects

por Keegan, Liam P., McGurk, Leeane, Palavicini, Juan Pablo, Brindle, James, Paro, Simona, Li, Xianghua, Rosenthal, Joshua J. C., O'Connell, Mary A.
Publicado 2011

Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

por Khan, Anzer, Paro, Simona, McGurk, Leeanne, Sambrani, Nagraj, Hogg, Marion C., Brindle, James, Pennetta, Giuseppa, Keegan, Liam P., O’Connell, Mary A.
Publicado 2020

Human BLCAP transcript: new editing events in normal and cancerous tissues

por Galeano, Federica, Leroy, Anne, Rossetti, Claudia, Gromova, Irina, Gautier, Philippe, Keegan, Liam P, Massimi, Luca, Di Rocco, Concezio, O'Connell, Mary A, Gallo, Angela
Publicado 2010

Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects

por Marcucci, Roberto, Brindle, James, Paro, Simona, Casadio, Angela, Hempel, Sophie, Morrice, Nicholas, Bisso, Andrea, Keegan, Liam P, Del Sal, Giannino, O'Connell, Mary A
Publicado 2011

Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

por Deng, Patricia, Khan, Anzer, Jacobson, Dionna, Sambrani, Nagraj, McGurk, Leeanne, Li, Xianghua, Jayasree, Aswathy, Hejatko, Jan, Shohat-Ophir, Galit, O’Connell, Mary A., Li, Jin Billy, Keegan, Liam P.
Publicado 2020

Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy

por Maroofian, Reza, Sedmík, Jiří, Mazaheri, Neda, Scala, Marcello, Zaki, Maha S, Keegan, Liam P, Azizimalamiri, Reza, Issa, Mahmoud, Shariati, Gholamreza, Sedaghat, Alireza, Beetz, Christian, Bauer, Peter, Galehdari, Hamid, O’Connell, Mary A, Houlden, Henry
Publicado 2021

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

por Mannion, Niamh M., Greenwood, Sam M., Young, Robert, Cox, Sarah, Brindle, James, Read, David, Nellåker, Christoffer, Vesely, Cornelia, Ponting, Chris P., McLaughlin, Paul J., Jantsch, Michael F., Dorin, Julia, Adams, Ian R., Scadden, A.D.J., Öhman, Marie, Keegan, Liam P., O’Connell, Mary A.
Publicado 2014