Which mouse multiparental population is right for your study? The Collaborative Cross inbred strains, their F1 hybrids, or the Diversity Outbred population

por Keele, Gregory R
Publicado 2023

The trouble with triples: Examining the impact of measurement error in mediation analysis

por Gastonguay, Madeleine S, Keele, Gregory R, Churchill, Gary A
Publicado 2023

Determinants of QTL Mapping Power in the Realized Collaborative Cross

por Keele, Gregory R., Crouse, Wesley L., Kelada, Samir N. P., Valdar, William
Publicado 2019

A Bayesian model selection approach to mediation analysis

por Crouse, Wesley L., Keele, Gregory R., Gastonguay, Madeleine S., Churchill, Gary A., Valdar, William
Publicado 2022

Inferring cell-type-specific causal gene regulatory networks during human neurogenesis

por Aygün, Nil, Liang, Dan, Crouse, Wesley L., Keele, Gregory R., Love, Michael I., Stein, Jason L.
Publicado 2023

Global and tissue-specific aging effects on murine proteomes

por Keele, Gregory R., Zhang, Ji-Gang, Szpyt, John, Korstanje, Ron, Gygi, Steven P., Churchill, Gary A., Schweppe, Devin K.
Publicado 2023

QTLViewer: an interactive webtool for genetic analysis in the Collaborative Cross and Diversity Outbred mouse populations

por Vincent, Matthew, Gerdes Gyuricza, Isabela, Keele, Gregory R, Gatti, Daniel M, Keller, Mark P, Broman, Karl W, Churchill, Gary A
Publicado 2022

Genome-wide transcript and protein analysis highlights the role of protein homeostasis in the aging mouse heart

por Gerdes Gyuricza, Isabela, Chick, Joel M., Keele, Gregory R., Deighan, Andrew G., Munger, Steven C., Korstanje, Ron, Gygi, Steven P., Churchill, Gary A.
Publicado 2022

An optogenetic switch for the Set2 methyltransferase provides evidence for transcription-dependent and -independent dynamics of H3K36 methylation

por Lerner, Andrew M., Hepperla, Austin J., Keele, Gregory R., Meriesh, Hashem A., Yumerefendi, Hayretin, Restrepo, David, Zimmerman, Seth, Bear, James E., Kuhlman, Brian, Davis, Ian J., Strahl, Brian D.
Publicado 2020

Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation

por Keele, Gregory R., Quach, Bryan C., Israel, Jennifer W., Chappell, Grace A., Lewis, Lauren, Safi, Alexias, Simon, Jeremy M., Cotney, Paul, Crawford, Gregory E., Valdar, William, Rusyn, Ivan, Furey, Terrence S.
Publicado 2020

Diagnostics and correction of batch effects in large‐scale proteomic studies: a tutorial

por Čuklina, Jelena, Lee, Chloe H, Williams, Evan G, Sajic, Tatjana, Collins, Ben C, Rodríguez Martínez, María, Sharma, Varun S, Wendt, Fabian, Goetze, Sandra, Keele, Gregory R, Wollscheid, Bernd, Aebersold, Ruedi, Pedrioli, Patrick G A
Publicado 2021

Regulation of protein abundance in genetically diverse mouse populations

por Keele, Gregory R., Zhang, Tian, Pham, Duy T., Vincent, Matthew, Bell, Timothy A., Hock, Pablo, Shaw, Ginger D., Paulo, Joao A., Munger, Steven C., Pardo-Manuel de Villena, Fernando, Ferris, Martin T., Gygi, Steven P., Churchill, Gary A.
Publicado 2021

Multi-omics analysis identifies drivers of protein phosphorylation

por Zhang, Tian, Keele, Gregory R., Gyuricza, Isabela Gerdes, Vincent, Matthew, Brunton, Catherine, Bell, Timothy A., Hock, Pablo, Shaw, Ginger D., Munger, Steven C., de Villena, Fernando Pardo-Manuel, Ferris, Martin T., Paulo, Joao A., Gygi, Steven P., Churchill, Gary A.
Publicado 2023

Genome-Wide Association Scan for Variants Associated with Early-Onset Prostate Cancer

por Lange, Ethan M., Johnson, Anna M., Wang, Yunfei, Zuhlke, Kimberly A., Lu, Yurong, Ribado, Jessica V., Keele, Gregory R., Li, Jin, Duan, Qing, Li, Ge, Gao, Zhengrong, Li, Yun, Xu, Jianfeng, Isaacs, William B., Zheng, Siqun, Cooney, Kathleen A.
Publicado 2014

Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice

por Maurizio, Paul L., Ferris, Martin T., Keele, Gregory R., Miller, Darla R., Shaw, Ginger D., Whitmore, Alan C., West, Ande, Morrison, Clayton R., Noll, Kelsey E., Plante, Kenneth S., Cockrell, Adam S., Threadgill, David W., Pardo-Manuel de Villena, Fernando, Baric, Ralph S., Heise, Mark T., Valdar, William
Publicado 2017

Sept8/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model

por Keele, Gregory R., Prokop, Jeremy W., He, Hong, Holl, Katie, Littrell, John, Deal, Aaron W., Kim, Yunjung, Kyle, Patrick B., Attipoe, Esinam, Johnson, Ashley C., Uhl, Katie L., Sirpilla, Olivia L., Jahanbakhsh, Seyedehameneh, Robinson, Melanie, Levy, Shawn, Valdar, William, Garrett, Michael R., Solberg Woods, Leah C.
Publicado 2021

Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression

por Yu, Qing, Liu, Xinyue, Keller, Mark P., Navarrete-Perea, Jose, Zhang, Tian, Fu, Sipei, Vaites, Laura P., Shuken, Steven R., Schmid, Ernst, Keele, Gregory R., Li, Jiaming, Huttlin, Edward L., Rashan, Edrees H., Simcox, Judith, Churchill, Gary A., Schweppe, Devin K., Attie, Alan D., Paulo, Joao A., Gygi, Steven P.
Publicado 2023

Genetic fine-mapping and identification of candidate genes and variants for adiposity traits in outbred rats

por Keele, Gregory R., Prokop, Jeremy W., He, Hong, Holl, Katie, Littrell, John, Deal, Aaron, Francic, Sanja, Cui, Leilei, Gatti, Daniel M., Broman, Karl W., Tschannen, Michael, Tsaih, Shirng-Wern, Zagloul, Maie, Kim, Yunjung, Baur, Brittany, Fox, Joseph, Robinson, Melanie, Levy, Shawn, Flister, Michael J., Mott, Richard, Valdar, William, Solberg Woods, Leah C
Publicado 2017

A large-scale genome-lipid association map guides lipid identification

por Linke, Vanessa, Overmyer, Katherine A., Miller, Ian J., Brademan, Dain R., Hutchins, Paul D., Trujillo, Edna A., Reddy, Thiru R., Russell, Jason D., Cushing, Emily M., Schueler, Kathryn L., Stapleton, Donald S., Rabaglia, Mary E., Keller, Mark P., Gatti, Daniel M., Keele, Gregory R., Pham, Duy, Broman, Karl W., Churchill, Gary A., Attie, Alan D., Coon, Joshua J.
Publicado 2020

Author Correction: Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut

por Zhang, Qijun, Linke, Vanessa, Overmyer, Katherine A., Traeger, Lindsay L., Kasahara, Kazuyuki, Miller, Ian J., Manson, Daniel E., Polaske, Thomas J., Kerby, Robert L., Kemis, Julia H., Trujillo, Edna A., Reddy, Thiru R., Russell, Jason D., Schueler, Kathryn L., Stapleton, Donald S., Rabaglia, Mary E., Seldin, Marcus, Gatti, Daniel M., Keele, Gregory R., Pham, Duy T., Gerdt, Joseph P., Vivas, Eugenio I., Lusis, Aldons J., Keller, Mark P., Churchill, Gary A., Blackwell, Helen E., Broman, Karl W., Attie, Alan D., Coon, Joshua J., Rey, Federico E.
Publicado 2023