p16(INK4a)-induced senescence is disabled by melanoma-associated mutations

por Haferkamp, Sebastian, Becker, Therese M, Scurr, Lyndee L, Kefford, Richard F, Rizos, Helen
Publicado 2008

A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapy

por Kefford, Richard F, Clingan, Philip R, Brady, Benjamin, Ballmer, Andrea, Morganti, Adele, Hersey, Peter
Publicado 2010

Liquid biomarkers in melanoma: detection and discovery

por Lim, Su Yin, Lee, Jenny H., Diefenbach, Russell J., Kefford, Richard F., Rizos, Helen
Publicado 2018

Interferon Signaling Is Frequently Downregulated in Melanoma

por Alavi, Sara, Stewart, Ashleigh Jacqueline, Kefford, Richard F., Lim, Su Yin, Shklovskaya, Elena, Rizos, Helen
Publicado 2018

The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence

por Haferkamp, Sebastian, Tran, Sieu L, Becker, Therese M, Scurr, Lyndee L, Kefford, Richard F, Rizos, Helen
Publicado 2009

Inter- and Intra-Patient Heterogeneity of Response and Progression to Targeted Therapy in Metastatic Melanoma

por Menzies, Alexander M., Haydu, Lauren E., Carlino, Matteo S., Azer, Mary W. F., Carr, Peter J. A., Kefford, Richard F., Long, Georgina V.
Publicado 2014

Cessation of targeted therapy after a complete response in BRAF-mutant advanced melanoma: a case series

por Carlino, Matteo S, Vanella, Vito, Girgis, Christina, Giannarelli, Diana, Guminski, Alex, Festino, Lucia, Kefford, Richard F, Menzies, Alexander M, Long, Georgina V, Ascierto, Paolo A
Publicado 2016

Targeted BRAF Inhibition Impacts Survival in Melanoma Patients with High Levels of Wnt/β-Catenin Signaling

por Chien, Andy J., Haydu, Lauren E., Biechele, Travis L., Kulikauskas, Rima M., Rizos, Helen, Kefford, Richard F., Scolyer, Richard A., Moon, Randall T., Long, Georgina V.
Publicado 2014

The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16(INK4a)

por Becker, Therese M, Haferkamp, Sebastian, Dijkstra, Menno K, Scurr, Lyndee L, Frausto, Monika, Diefenbach, Eve, Scolyer, Richard A, Reisman, David N, Mann, Graham J, Kefford, Richard F, Rizos, Helen
Publicado 2009

Evaluation of stromal HGF immunoreactivity as a biomarker for melanoma response to RAF inhibitors

por Lezcano, Cecilia, Lee, Chung-Wei, Larson, Allison R., Menzies, Alexander M., Kefford, Richard F., Thompson, John F., Mihm, Martin C., Ogino, Shuji, Long, Georgina V., Scolyer, Richard A., Murphy, George F.
Publicado 2014

Clinical significance of intronic variants in BRAF inhibitor resistant melanomas with altered BRAF transcript splicing

por Pupo, Gulietta M., Boyd, Suzanah C., Fung, Carina, Carlino, Matteo S., Menzies, Alexander M., Pedersen, Bernadette, Johansson, Peter, Hayward, Nicholas K., Kefford, Richard F., Scolyer, Richard A., Long, Georgina V., Rizos, Helen
Publicado 2017

Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients

por Lim, Su Yin, Lee, Jenny H., Welsh, Sarah J., Ahn, Seong Beom, Breen, Edmond, Khan, Alamgir, Carlino, Matteo S., Menzies, Alexander M., Kefford, Richard F., Scolyer, Richard A., Long, Georgina V., Rizos, Helen
Publicado 2017

Design and Testing of a Custom Melanoma Next Generation Sequencing Panel for Analysis of Circulating Tumor DNA

por Diefenbach, Russell J., Lee, Jenny H., Menzies, Alexander M., Carlino, Matteo S., Long, Georgina V., Saw, Robyn P. M., Howle, Julie R., Spillane, Andrew J., Scolyer, Richard A., Kefford, Richard F., Rizos, Helen
Publicado 2020

Oncogenic B-RAF(V600E) signaling induces the T-box3 transcriptional repressor to repress E-cadherin and enhance melanoma cell invasion

por Boyd, Suzanah C., Mijatov, Branka, Pupo, Gulietta M., Tran, Sieu L., Gowrishankar, Kavitha, Shaw, Heather M., Goding, Colin R., Scolyer, Richard A., Mann, Graham J., Kefford, Richard F., Rizos, Helen, Becker, Therese M.
Publicado 2012

Tumor MHC Expression Guides First-Line Immunotherapy Selection in Melanoma

por Shklovskaya, Elena, Lee, Jenny H, Lim, Su Yin, Stewart, Ashleigh, Pedersen, Bernadette, Ferguson, Peter, Saw, Robyn PM, Thompson, John F, Shivalingam, Brindha, Carlino, Matteo S, Scolyer, Richard A, Menzies, Alexander M, Long, Georgina V, Kefford, Richard F, Rizos, Helen
Publicado 2020

Melanoma whole exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance

por Shi, Hubing, Moriceau, Gatien, Kong, Xiangju, Lee, Mi-Kyung, Lee, Hane, Koya, Richard C., Ng, Charles, Chodon, Thinle, Scolyer, Richard A., Dahlman, Kimberly B., Sosman, Jeffrey A., Kefford, Richard F., Long, Georgina V., Nelson, Stanley F., Ribas, Antoni, Lo, Roger S.
Publicado 2012

Efficacy of anti-PD-1 therapy in patients with melanoma brain metastases

por Parakh, Sagun, Park, John J, Mendis, Shehara, Rai, Rajat, Xu, Wen, Lo, Serigne, Drummond, Martin, Rowe, Catherine, Wong, Annie, McArthur, Grant, Haydon, Andrew, Andrews, Miles C, Cebon, Jonathan, Guminski, Alex, Kefford, Richard F, Long, Georgina V, Menzies, Alexander M, Klein, Oliver, Carlino, Matteo S
Publicado 2017

Analysis of the Whole-Exome Sequencing of Tumor and Circulating Tumor DNA in Metastatic Melanoma

por Diefenbach, Russell J., Lee, Jenny H., Strbenac, Dario, Yang, Jean Y. H., Menzies, Alexander M., Carlino, Matteo S., Long, Georgina V., Spillane, Andrew J., Stretch, Jonathan R., Saw, Robyn P. M., Thompson, John F., Ch’ng, Sydney, Scolyer, Richard A., Kefford, Richard F., Rizos, Helen
Publicado 2019

Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition

por Lee, Jenny H., Shklovskaya, Elena, Lim, Su Yin, Carlino, Matteo S., Menzies, Alexander M., Stewart, Ashleigh, Pedersen, Bernadette, Irvine, Malama, Alavi, Sara, Yang, Jean Y. H., Strbenac, Dario, Saw, Robyn P. M., Thompson, John F., Wilmott, James S., Scolyer, Richard A., Long, Georgina V., Kefford, Richard F., Rizos, Helen
Publicado 2020

MC1R genotype as a predictor of early-onset melanoma, compared with self-reported and physician-measured traditional risk factors: an Australian case-control-family study

por Cust, Anne E, Goumas, Chris, Vuong, Kylie, Davies, John R, Barrett, Jennifer H, Holland, Elizabeth A, Schmid, Helen, Agha-Hamilton, Chantelle, Armstrong, Bruce K, Kefford, Richard F, Aitken, Joanne F, Giles, Graham G, Bishop, D Timothy, Newton-Bishop, Julia A, Hopper, John L, Mann, Graham J, Jenkins, Mark A
Publicado 2013