3. EXCITATION-INHIBITION IMBALANCES IN SCHIZOPHRENIA: MECHANISMS AND INTERVENTIONS

por Kegeles, Lawrence
Publicado 2018

43.4 THE ROLE OF MOLECULAR IMAGING IN GUIDING DRUG DEVELOPMENT

por Abi-Dargham, Anissa, Kegeles, Lawrence, Slifstein, Mark
Publicado 2018

Ventromedial prefrontal cortex/anterior cingulate cortex Glx, glutamate, and GABA levels in medication-free major depressive disorder

por Kantrowitz, Joshua T., Dong, Zhengchao, Milak, Matthew S., Rashid, Rain, Kegeles, Lawrence S., Javitt, Daniel C., Lieberman, Jeffrey A., John Mann, J.
Publicado 2021

GABA level, gamma oscillation, and working memory performance in schizophrenia

por Chen, Chi-Ming A., Stanford, Arielle D., Mao, Xiangling, Abi-Dargham, Anissa, Shungu, Dikoma C., Lisanby, Sarah H., Schroeder, Charles E., Kegeles, Lawrence S.
Publicado 2014

Detecting schizophrenia with 3D structural brain MRI using deep learning

por Zhang, Junhao, Rao, Vishwanatha M., Tian, Ye, Yang, Yanting, Acosta, Nicolas, Wan, Zihan, Lee, Pin-Yu, Zhang, Chloe, Kegeles, Lawrence S., Small, Scott A., Guo, Jia
Publicado 2023

Striatal Dopamine Release in Schizophrenia Comorbid with Substance Dependence

por Thompson, Judy L., Urban, Nina, Slifstein, Mark, Xu, Xiaoyan, Kegeles, Lawrence S., Girgis, Ragy R., Beckerman, Yael, Harkavy-Friedman, Jill M., Gil, Roberto, Abi-Dargham, Anissa
Publicado 2012

PET imaging of dopamine-D2 receptor internalization in schizophrenia

por Weinstein, Jodi J., van de Giessen, Elsmarieke, Rosengard, Rachel J., Xu, Xiaoyan, Ojeil, Najate, Brucato, Gary, Gil, Roberto B., Kegeles, Lawrence S., Laruelle, Marc, Slifstein, Mark, Abi-Dargham, Anissa
Publicado 2017

3.3 DISTURBANCES IN NEURAL OSCILLATIONS, GLUTAMATE, AND GABA: EFFECTS OF KETAMINE AND COMPARISON TO SCHIZOPHRENIA

por Kegeles, Lawrence, Stolz, Erin, Mao, Xiangling, Ojeil, Najate, Massuda, Raphael, Pedrini, Mariana, Bayatmokhtari, Maryam, Slifstein, Mark, Abi-Dargham, Anissa, Milak, Matthew, Rodriguez, Carolyn, Chen, Chi-Ming, Shungu, Dikoma
Publicado 2018

Deficits in striatal dopamine release in cannabis dependence

por van de Giessen, Elsmarieke, Weinstein, Jodi J., Cassidy, Clifford M., Haney, Margaret, Dong, Zhengchao, Ghazzaoui, Rassil, Ojeil, Najate, Kegeles, Lawrence S., Xu, Xiaoyan, Vadhan, Nehal P., Volkow, Nora D., Slifstein, Mark, Abi-Dargham, Anissa
Publicado 2016

Assessment of Relationship of Ketamine Dose With Magnetic Resonance Spectroscopy of Glx and GABA Responses in Adults With Major Depression: A Randomized Clinical Trial

por Milak, Matthew S., Rashid, Rain, Dong, Zhengchao, Kegeles, Lawrence S., Grunebaum, Michael F., Ogden, R. Todd, Lin, Xuejing, Mulhern, Stephanie T., Suckow, Raymond F., Cooper, Thomas B., Keilp, John G., Mao, Xiangling, Shungu, Dikoma C., Mann, J. John
Publicado 2020

A Pilot In Vivo Proton Magnetic Resonance Spectroscopy Study of Amino Acid Neurotransmitter Response to Ketamine Treatment of Major Depressive Disorder

por Milak, Matthew S., Proper, Caitlin J., Mulhern, Stephanie T., Parter, Amy L., Kegeles, Lawrence S., Ogden, R. Todd, Mao, Xiangling, Rodriguez, Carolyn I., Oquendo, Maria A., Suckow, Raymond F., Cooper, Thomas B., Keilp, John C., Shungu, Dikoma C., Mann, J. John
Publicado 2015

Proof of mechanism and target engagement of glutamatergic drugs for the treatment of schizophrenia: RCTs of pomaglumetad and TS-134 on ketamine-induced psychotic symptoms and pharm...

por Kantrowitz, Joshua T., Grinband, Jack, Goff, Donald C., Lahti, Adrienne C., Marder, Stephen R., Kegeles, Lawrence S., Girgis, Ragy R., Sobeih, Tarek, Wall, Melanie M., Choo, Tse-Hwei, Green, Michael F., Yang, Yvonne S., Lee, Junghee, Horga, Guillermo, Krystal, John H., Potter, William Z., Javitt, Daniel C., Lieberman, Jeffrey A.
Publicado 2020

A multicenter study of ketamine effects on functional connectivity: Large scale network relationships, hubs and symptom mechanisms

por Fleming, Leah M., Javitt, Daniel C., Carter, Cameron S., Kantrowitz, Joshua T., Girgis, Ragy R., Kegeles, Lawrence S., Ragland, John D., Maddock, Richard J., Lesh, Tyler A., Tanase, Costin, Robinson, James, Potter, William Z., Carlson, Marlene, Wall, Melanie M., Choo, Tse-Hwei, Grinband, Jack, Lieberman, Jeffrey, Krystal, John H., Corlett, Philip R.
Publicado 2019

Grant Report on d-Serine Augmentation of Neuroplasticity-Based Auditory Learning in Schizophrenia (†)

por de la Garrigue, Natalie, Glasser, Juliana, Sehatpour, Pejman, Iosifescu, Dan V., Dias, Elisa, Carlson, Marlene, Shope, Constance, Sobeih, Tarek, Choo, Tse-Hwei, Wall, Melanie M., Kegeles, Lawrence S., Gangwisch, James, Mayer, Megan, Brazis, Stephanie, De Baun, Heloise M., Wolfer, Stephanie, Bermudez, Dalton, Arnold, Molly, Rette, Danielle, Meftah, Amir M., Conant, Melissa, Lieberman, Jeffrey A., Kantrowitz, Joshua T.
Publicado 2020

Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual...

por Merritt, Kate, McGuire, Philip K., Egerton, Alice, Aleman, André, Block, Wolfgang, Bloemen, Oswald J. N., Borgan, Faith, Bustillo, Juan R., Capizzano, Aristides A., Coughlin, Jennifer Marie, De la Fuente-Sandoval, Camilo, Demjaha, Arsime, Dempster, Kara, Do, Kim Q., Du, Fei, Falkai, Peter, Galinska-Skok, Beata, Gallinat, Jurgen, Gasparovic, Charles, Ginestet, Cedric E., Goto, Naoki, Graff-Guerrero, Ariel, Ho, Beng Choon, Howes, Oliver D., Jauhar, Sameer, Jeon, Peter, Kato, Tadafumi, Kaufmann, Charles A., Kegeles, Lawrence S., Keshavan, Matcheri, Kim, Sang-Young, Kunugi, Hiroshi, Lauriello, John, Liemburg, Edith Jantine, Mcilwain, Meghan E., Modinos, Gemma, Mouchlianitis, Elias D., Nakamura, Jun, Nenadic, Igor, Öngür, Dost, Ota, Miho, Palaniyappan, Lena, Pantelis, Christos, Plitman, Eric, Posporelis, Sotirios, Purdon, Scot E., Reichenbach, Jürgen R., Renshaw, Perry F., Russell, Bruce R., Sawa, Akira, Schaefer, Martin, Shungu, Dikoma C., Smesny, Stefan, Stanley, Jeffrey A., Stone, James M., Szulc, Agata, Taylor, Reggie, Thakkar, Katy, Théberge, Jean, Tibbo, Philip G., van Amelsvoort, Therese, Walecki, Jerzy, Williamson, Peter C., Wood, Stephen James, Xin, Lijing, Yamasue, Hidenori
Publicado 2021

Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis

por Merritt, Kate, McCutcheon, Robert A., Aleman, André, Ashley, Sarah, Beck, Katherine, Block, Wolfgang, Bloemen, Oswald J. N., Borgan, Faith, Boules, Christiana, Bustillo, Juan R., Capizzano, Aristides A., Coughlin, Jennifer M., David, Anthony, de la Fuente-Sandoval, Camilo, Demjaha, Arsime, Dempster, Kara, Do, Kim Q., Du, Fei, Falkai, Peter, Galińska-Skok, Beata, Gallinat, Jürgen, Gasparovic, Charles, Ginestet, Cedric E., Goto, Naoki, Graff-Guerrero, Ariel, Ho, Beng-Choon, Howes, Oliver, Jauhar, Sameer, Jeon, Peter, Kato, Tadafumi, Kaufmann, Charles A., Kegeles, Lawrence S., Keshavan, Matcheri S., Kim, Sang-Young, King, Bridget, Kunugi, Hiroshi, Lauriello, J., León-Ortiz, Pablo, Liemburg, Edith, Mcilwain, Meghan E., Modinos, Gemma, Mouchlianitis, Elias, Nakamura, Jun, Nenadic, Igor, Öngür, Dost, Ota, Miho, Palaniyappan, Lena, Pantelis, Christos, Patel, Tulsi, Plitman, Eric, Posporelis, Sotirios, Purdon, Scot E., Reichenbach, Jürgen R., Renshaw, Perry F., Reyes-Madrigal, Francisco, Russell, Bruce R., Sawa, Akira, Schaefer, Martin, Shungu, Dikoma C., Smesny, Stefan, Stanley, Jeffrey A., Stone, James, Szulc, Agata, Taylor, Reggie, Thakkar, Katharine N., Théberge, Jean, Tibbo, Philip G., van Amelsvoort, Thérèse, Walecki, Jerzy, Williamson, Peter C., Wood, Stephen J., Xin, Lijing, Yamasue, Hidenori, McGuire, Philip, Egerton, Alice
Publicado 2023