α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation

por Hyvönen, Mervi T., Khomutov, Maxim, Vepsäläinen, Jouko, Khomutov, Alex R., Keinänen, Tuomo A.
Publicado 2021

Controlling the regioselectivity and stereospecificity of FAD-dependent polyamine oxidases with the use of amine-attached guide molecules as conformational modulators

por Keinänen, Tuomo A., Grigorenko, Nikolay, Khomutov, Alex R., Huang, Qingqiu, Uimari, Anne, Alhonen, Leena, Hyvönen, Mervi T., Vepsäläinen, Jouko
Publicado 2018

Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes

por Vuohelainen, Susanna, Pirinen, Eija, Cerrada-Gimenez, Marc, Keinänen, Tuomo A, Uimari, Anne, Pietilä, Marko, Khomutov, Alex R, Jänne, Juhani, Alhonen, Leena
Publicado 2010

Mice with targeted disruption of spermidine/spermine N(1)-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging

por Niiranen, Kirsi, Keinänen, Tuomo A, Pirinen, Eija, Heikkinen, Sami, Tusa, Maija, Fatrai, Szabolcs, Suppola, Suvikki, Pietilä, Marko, Uimari, Anne, Laakso, Markku, Alhonen, Leena, Jänne, Juhani
Publicado 2006

Hydroxylamine Analogue of Agmatine: Magic Bullet for Arginine Decarboxylase

por Hyvönen, Mervi T., Keinänen, Tuomo A., Nuraeva, Gulgina K., Yanvarev, Dmitry V., Khomutov, Maxim, Khurs, Elena N., Kochetkov, Sergey N., Vepsäläinen, Jouko, Zhgun, Alexander A., Khomutov, Alex R.
Publicado 2020

Unforeseen Possibilities To Investigate the Regulation of Polyamine Metabolism Revealed by Novel C-Methylated Spermine Derivatives

por Khomutov, Maxim, Hyvönen, Mervi T., Simonian, Alina, Formanovsky, Andrey A., Mikhura, Irina V., Chizhov, Alexander O., Kochetkov, Sergey N., Alhonen, Leena, Vepsäläinen, Jouko, Keinänen, Tuomo A., Khomutov, Alex R.
Publicado 2019

Activation of Polyamine Catabolism by N(1),N(11)-Diethylnorspermine in Hepatic HepaRG Cells Induces Dedifferentiation and Mesenchymal-Like Phenotype

por Ivanova, Olga N., Snezhkina, Anastasiya V., Krasnov, George S., Valuev-Elliston, Vladimir T., Khomich, Olga A., Khomutov, Alexey R., Keinanen, Tuomo A., Alhonen, Leena, Bartosch, Birke, Kudryavtseva, Anna V., Kochetkov, Sergey N., Ivanov, Alexander V.
Publicado 2018

Role of Polyamine-Induced Dimerization of Antizyme in Its Cellular Functions

por Hyvönen, Mervi T., Smirnova, Olga A., Mitkevich, Vladimir A., Tunitskaya, Vera L., Khomutov, Maxim, Karpov, Dmitry S., Korolev, Sergey P., Häkkinen, Merja R., Pietilä, Marko, Gottikh, Marina B., Vepsäläinen, Jouko, Alhonen, Leena, Makarov, Alexander A., Kochetkov, Sergey N., Wallace, Heather M., Keinänen, Tuomo A., Khomutov, Alex R.
Publicado 2022